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Protein
Submitted name:

Lactate/malate dehydrogenase family protein

Gene

At5g58330

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • malate dehydrogenase (NADP+) activity Source: InterPro
  • NAD(P)+ transhydrogenase activity Source: TAIR

GO - Biological processi

  • carbohydrate metabolic process Source: InterPro
  • malate metabolic process Source: InterPro
  • response to redox state Source: TAIR
Complete GO annotation...

Enzyme and pathway databases

BioCyciARA:AT5G58330-MONOMER.
BRENDAi1.1.1.40. 399.

Names & Taxonomyi

Protein namesi
Submitted name:
Lactate/malate dehydrogenase family proteinImported
Submitted name:
NADP-dependent malate dehydrogenaseImported
Gene namesi
Ordered Locus Names:At5g58330Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G58330.

Subcellular locationi

GO - Cellular componenti

  • apoplast Source: TAIR
  • chloroplast Source: TAIR
  • chloroplast envelope Source: TAIR
  • chloroplast stroma Source: TAIR
  • mitochondrion Source: TAIR
  • thylakoid Source: TAIR
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G58330.1.

Structurei

3D structure databases

SMRiQ8H1E2. Positions 72-443.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini101 – 248148Ldh_1_NInterPro annotationAdd
BLAST
Domaini251 – 420170Ldh_1_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1496. Eukaryota.
COG0039. LUCA.
HOGENOMiHOG000220953.
OMAiAFSQECI.
OrthoDBiEOG09360AEK.
PhylomeDBiQ8H1E2.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
HAMAPiMF_01517. Malate_dehydrog_2. 1 hit.
InterProiIPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR011273. Malate_DH_NADP-dep_pln.
IPR010945. Malate_DH_type2.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23382. PTHR23382. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF56327. SSF56327. 1 hit.
TIGRFAMsiTIGR01757. Malate-DH_plant. 1 hit.
TIGR01759. MalateDH-SF1. 1 hit.
PROSITEiPS00068. MDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8H1E2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMAELSTPK TTSPFLNSSS RLRLSSKLHL SNHFRHLLLP PLHTTTPNSK
60 70 80 90 100
ISCSVSQNSQ APVAVQENGL VKTKKECYGV FCLTYDLKAE EETRSWKKLI
110 120 130 140 150
NIAVSGAAGM ISNHLLFKLA SGEVFGPDQP IALKLLGSER SIQALEGVAM
160 170 180 190 200
ELEDSLFPLL REVDIGTDPN EVFQDVEWAI LIGAKPRGPG MERADLLDIN
210 220 230 240 250
GQIFAEQGKA LNKAASPNVK VLVVGNPCNT NALICLKNAP NIPAKNFHAL
260 270 280 290 300
TRLDENRAKC QLALKAGVFY DKVSNMTIWG NHSTTQVPDF LNARINGLPV
310 320 330 340 350
KEVITDHKWL EEGFTESVQK RGGLLIQKWG RSSAASTAVS IVDAIKSLVT
360 370 380 390 400
PTPEGDWFST GVYTDGNPYG IEEGLVFSMP CRSKGDGDYE LVKDVEIDDY
410 420 430 440
LRQRIAKSEA ELLAEKRCVA HLTGEGIAYC DLGPVDTMLP GEV
Length:443
Mass (Da):48,316
Last modified:March 1, 2003 - v1
Checksum:i29BE4C23B9E94F41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY150479 mRNA. Translation: AAN13004.1.
CP002688 Genomic DNA. Translation: AED97038.1.
AK226364 mRNA. Translation: BAE98512.1.
RefSeqiNP_851214.1. NM_180883.3.
UniGeneiAt.71066.
At.9574.

Genome annotation databases

EnsemblPlantsiAT5G58330.1; AT5G58330.1; AT5G58330.
GeneIDi835945.
GrameneiAT5G58330.1; AT5G58330.1; AT5G58330.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY150479 mRNA. Translation: AAN13004.1.
CP002688 Genomic DNA. Translation: AED97038.1.
AK226364 mRNA. Translation: BAE98512.1.
RefSeqiNP_851214.1. NM_180883.3.
UniGeneiAt.71066.
At.9574.

3D structure databases

SMRiQ8H1E2. Positions 72-443.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G58330.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G58330.1; AT5G58330.1; AT5G58330.
GeneIDi835945.
GrameneiAT5G58330.1; AT5G58330.1; AT5G58330.

Organism-specific databases

TAIRiAT5G58330.

Phylogenomic databases

eggNOGiKOG1496. Eukaryota.
COG0039. LUCA.
HOGENOMiHOG000220953.
OMAiAFSQECI.
OrthoDBiEOG09360AEK.
PhylomeDBiQ8H1E2.

Enzyme and pathway databases

BioCyciARA:AT5G58330-MONOMER.
BRENDAi1.1.1.40. 399.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
HAMAPiMF_01517. Malate_dehydrog_2. 1 hit.
InterProiIPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR011273. Malate_DH_NADP-dep_pln.
IPR010945. Malate_DH_type2.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23382. PTHR23382. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF56327. SSF56327. 1 hit.
TIGRFAMsiTIGR01757. Malate-DH_plant. 1 hit.
TIGR01759. MalateDH-SF1. 1 hit.
PROSITEiPS00068. MDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8H1E2_ARATH
AccessioniPrimary (citable) accession number: Q8H1E2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.