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Q8H016

- LOX6_ORYSJ

UniProt

Q8H016 - LOX6_ORYSJ

Protein

Probable lipoxygenase 6

Gene

Os03g0179900

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 2 (30 Aug 2005)
      Previous versions | rss
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    Functioni

    Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure By similarity.By similarity

    Catalytic activityi

    Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.
    Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

    Cofactori

    Binds 1 iron ion per subunit. Iron is tightly bound By similarity.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi573 – 5731Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi578 – 5781Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi765 – 7651Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi769 – 7691Iron; catalyticPROSITE-ProRule annotation
    Metal bindingi918 – 9181Iron; via carboxylate; catalyticPROSITE-ProRule annotation

    GO - Molecular functioni

    1. iron ion binding Source: InterPro
    2. linoleate 13S-lipoxygenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. anther dehiscence Source: EnsemblPlants/Gramene
    2. lipid oxidation Source: EnsemblPlants/Gramene
    3. oxylipin biosynthetic process Source: UniProtKB-UniPathway
    4. pollen development Source: EnsemblPlants/Gramene
    5. response to bacterium Source: EnsemblPlants/Gramene
    6. response to fungus Source: EnsemblPlants/Gramene
    7. response to high light intensity Source: EnsemblPlants/Gramene
    8. response to jasmonic acid Source: EnsemblPlants/Gramene
    9. response to ozone Source: EnsemblPlants/Gramene
    10. response to wounding Source: EnsemblPlants/Gramene
    11. stamen filament development Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Dioxygenase, Oxidoreductase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Oxylipin biosynthesis

    Keywords - Ligandi

    Iron, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00382.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable lipoxygenase 6 (EC:1.13.11.12)
    Gene namesi
    Ordered Locus Names:Os03g0179900, LOC_Os03g08220
    ORF Names:OSJNBa0050H14.14, OSJNBb0076N15.1
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 3

    Organism-specific databases

    GrameneiQ8H016.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 918918Probable lipoxygenase 6PRO_0000220712Add
    BLAST

    Proteomic databases

    PRIDEiQ8H016.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini90 – 218129PLATPROSITE-ProRule annotationAdd
    BLAST
    Domaini221 – 918698LipoxygenasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the lipoxygenase family.Curated
    Contains 1 lipoxygenase domain.PROSITE-ProRule annotation
    Contains 1 PLAT domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG69653.
    HOGENOMiHOG000230469.
    KOiK00454.
    OMAiLSKDKFA.

    Family and domain databases

    Gene3Di2.60.60.20. 1 hit.
    4.10.372.10. 1 hit.
    InterProiIPR008976. Lipase_LipOase.
    IPR000907. LipOase.
    IPR013819. LipOase_C.
    IPR020834. LipOase_CS.
    IPR020833. LipOase_Fe_BS.
    IPR001246. LipOase_pln.
    IPR027433. Lipoxygenase_domain_3.
    IPR001024. PLAT/LH2_dom.
    [Graphical view]
    PANTHERiPTHR11771. PTHR11771. 1 hit.
    PfamiPF00305. Lipoxygenase. 1 hit.
    PF01477. PLAT. 1 hit.
    [Graphical view]
    PRINTSiPR00087. LIPOXYGENASE.
    PR00468. PLTLPOXGNASE.
    SMARTiSM00308. LH2. 1 hit.
    [Graphical view]
    SUPFAMiSSF48484. SSF48484. 1 hit.
    SSF49723. SSF49723. 1 hit.
    PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
    PS00081. LIPOXYGENASE_2. 1 hit.
    PS51393. LIPOXYGENASE_3. 1 hit.
    PS50095. PLAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8H016-1 [UniParc]FASTAAdd to Basket

    « Hide

    MELTGLTRAA AAATVTPPAP RRGWGELRFA PLLPGERHGR RKVVVAAISE    50
    EVPRLAASPS SGIKGGGAGE RRPAPEKVAL RAALTVRRKQ KEDIKEAVAG 100
    HLDALWDMVG RNVVLELIST KIHPRTKKPM QSGRVSIKDW CQKRGAKGDH 150
    VVYTAEFTVD ADFGEPGAIA VANRHNREFF LESIVVEGGG LPCGPVHFAC 200
    NSWVQSTREL PTKRVFFSNK PYLPSETPPG LRELREKELK DLRGDGTGVR 250
    KLSDRIYDYA TYNDLGNPDK GKEFIRPILG GEKIPYPRRC RTGRPPTDTN 300
    MLAESRVEKP HPIYVPRDEA FEELKQGAFS SGRLRAVLHT LIPSLIASIS 350
    AETHNFQGFH HIDNLYKEGL RLKLGLQEHL FQKIPLVQKI QESSEGMLRY 400
    DTPSILSKDK FAWLRDDEFA RQAVAGINPV NIERLQVFPP VSKLDPAIYG 450
    PPESSITETH IAGHLNGLTV QQAMDEAKLF IVDYHDAYLP FLDRINAIDG 500
    RKAYATRTIF FLTEAGTLKP IAIELSLPPA KPGEPRPSKV LTPPYDATSN 550
    WLWMLAKAHV SSNDAGVHQL VNHWLRTHAT MEPFILAAHR HMSAMHPIFK 600
    LLHPHMRYTL EINALARQSL INADGVIESC FTPGPVSGEI SAAYYRNHWR 650
    FDLEGLPSDL IRRGVAVEDA TQPHGVRLLI EDYPYANDGL LLWSAIRSWV 700
    ESYVQLYYPD AGTVQCDLEL QGWYHESIHV GHGDLRHAPW WPPLSTPVDL 750
    ASILTTLVWL ASAQHAALNF GQYPLGGYVP NRPPLIRRLL PDLERDAAEY 800
    AAFLADPHRF FLNAMPGVLE ATKFMAVVDT LSTHSPDEEY LGEGRDEGGV 850
    PWTADEAAVA AHGMFAADVR RAEETIERRN ADHGRKNRCG AGVLPYELLA 900
    PSSPPGVTCR GVPNSISI 918
    Length:918
    Mass (Da):101,959
    Last modified:August 30, 2005 - v2
    Checksum:i25BB8DD1E7906CF8
    GO

    Sequence cautioni

    The sequence AAN65431.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence AAO13474.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC125472 Genomic DNA. Translation: AAO13474.1. Sequence problems.
    AC126223 Genomic DNA. Translation: AAN65431.1. Sequence problems.
    AK121637 mRNA. No translation available.
    RefSeqiNP_001049158.1. NM_001055693.1.
    UniGeneiOs.9616.

    Genome annotation databases

    EnsemblPlantsiOS03T0179900-01; OS03T0179900-01; OS03G0179900.
    GeneIDi4331824.
    KEGGiosa:4331824.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC125472 Genomic DNA. Translation: AAO13474.1 . Sequence problems.
    AC126223 Genomic DNA. Translation: AAN65431.1 . Sequence problems.
    AK121637 mRNA. No translation available.
    RefSeqi NP_001049158.1. NM_001055693.1.
    UniGenei Os.9616.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8H016.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS03T0179900-01 ; OS03T0179900-01 ; OS03G0179900 .
    GeneIDi 4331824.
    KEGGi osa:4331824.

    Organism-specific databases

    Gramenei Q8H016.

    Phylogenomic databases

    eggNOGi NOG69653.
    HOGENOMi HOG000230469.
    KOi K00454.
    OMAi LSKDKFA.

    Enzyme and pathway databases

    UniPathwayi UPA00382 .

    Family and domain databases

    Gene3Di 2.60.60.20. 1 hit.
    4.10.372.10. 1 hit.
    InterProi IPR008976. Lipase_LipOase.
    IPR000907. LipOase.
    IPR013819. LipOase_C.
    IPR020834. LipOase_CS.
    IPR020833. LipOase_Fe_BS.
    IPR001246. LipOase_pln.
    IPR027433. Lipoxygenase_domain_3.
    IPR001024. PLAT/LH2_dom.
    [Graphical view ]
    PANTHERi PTHR11771. PTHR11771. 1 hit.
    Pfami PF00305. Lipoxygenase. 1 hit.
    PF01477. PLAT. 1 hit.
    [Graphical view ]
    PRINTSi PR00087. LIPOXYGENASE.
    PR00468. PLTLPOXGNASE.
    SMARTi SM00308. LH2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48484. SSF48484. 1 hit.
    SSF49723. SSF49723. 1 hit.
    PROSITEi PS00711. LIPOXYGENASE_1. 1 hit.
    PS00081. LIPOXYGENASE_2. 1 hit.
    PS51393. LIPOXYGENASE_3. 1 hit.
    PS50095. PLAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
      The rice chromosome 3 sequencing consortium
      Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S.
      , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
      Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiLOX6_ORYSJ
    AccessioniPrimary (citable) accession number: Q8H016
    Secondary accession number(s): Q8H7L4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: August 30, 2005
    Last modified: October 1, 2014
    This is version 79 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3