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Protein

Cyclin-T1-4

Gene

CYCT1-4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell cycle Source: UniProtKB-KW
  • cell division Source: UniProtKB-KW
  • leaf development Source: TAIR
  • positive regulation of cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
  • positive regulation of phosphorylation of RNA polymerase II C-terminal domain Source: GO_Central
  • positive regulation of transcription from RNA polymerase II promoter Source: GO_Central
  • response to virus Source: TAIR
  • trichome morphogenesis Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Cyclin

Keywords - Biological processi

Cell cycle, Cell division

Enzyme and pathway databases

ReactomeiR-ATH-112382. Formation of RNA Pol II elongation complex.
R-ATH-674695. RNA Polymerase II Pre-transcription Events.
R-ATH-6796648. TP53 Regulates Transcription of DNA Repair Genes.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-T1-4
Short name:
CycT1;4
Alternative name(s):
Protein AtCycT-like2
Gene namesi
Name:CYCT1-4
Ordered Locus Names:At4g19600
ORF Names:F24J7.161
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G19600.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 541541Cyclin-T1-4PRO_0000287056Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei396 – 3961PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8GYM6.
PRIDEiQ8GYM6.

PTM databases

iPTMnetiQ8GYM6.

Expressioni

Gene expression databases

GenevisibleiQ8GYM6. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G19600.1.

Structurei

3D structure databases

ProteinModelPortaliQ8GYM6.
SMRiQ8GYM6. Positions 32-269.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin T subfamily.Curated

Phylogenomic databases

eggNOGiKOG0834. Eukaryota.
COG5333. LUCA.
HOGENOMiHOG000220828.
InParanoidiQ8GYM6.
KOiK15188.
OMAiDFNVYHP.
PhylomeDBiQ8GYM6.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR013763. Cyclin-like.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8GYM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVLAGDCS FGESGVSSYS RNSNEKQDEV ARWYFGRKEI EENSPSRLDS
60 70 80 90 100
IDLKKETYLR KSYCTFLQDL GMRLKVPQVT IATAIIFCHR FFIRQSHARN
110 120 130 140 150
DRRTIATVCM FLAGKVEETP RPLKDVIVVS YEIIHKKDPT TAQKIKQKEV
160 170 180 190 200
YEQQKELILN GEKIVLSTLG FDFNVYHPYK PLVEAIKKFK VAQNALAQVA
210 220 230 240 250
WNFVNDGLRT SLCLQFKPHH IAAGAIFLAA KFLKVKLPSD GEKVWWQEFD
260 270 280 290 300
VTPRQLEDVS NQMLELYEQN RVPASQVSEV ESSVGGGSAH HVGSRPSARL
310 320 330 340 350
THEHSNSDNL GGSTKATQNR SNDNGSGEAG SVITEQKGER DTETKDSMHT
360 370 380 390 400
ESHPAHKSRS GVEAPGEDKI EKAGAHFPED DKSRIVGTAD VTVSQSPKDI
410 420 430 440 450
KMFRDKVKAK LEAKKVQGEK TRKKDLVDED DLIERELEDV ELAVEDDKDI
460 470 480 490 500
QNKSSMGTEH GEILDGNNLV VNTEEGEMID DVSSTMPSRK RKMESPCEKQ
510 520 530 540
LGEGKRRHDN SENVEEGQKT NPGGSSHSYG DREPRRHSQE R
Length:541
Mass (Da):60,710
Last modified:March 1, 2003 - v1
Checksum:i52766E85673FEE2B
GO

Sequence cautioni

The sequence CAB40377.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAB78962.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021768 Genomic DNA. Translation: CAB40377.1. Sequence problems.
AL161551 Genomic DNA. Translation: CAB78962.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84203.1.
AK117509 mRNA. Translation: BAC42172.1.
BT029301 mRNA. Translation: ABK32115.1.
PIRiT06153.
RefSeqiNP_193695.2. NM_118080.2.
UniGeneiAt.32800.

Genome annotation databases

EnsemblPlantsiAT4G19600.1; AT4G19600.1; AT4G19600.
GeneIDi827702.
GrameneiAT4G19600.1; AT4G19600.1; AT4G19600.
KEGGiath:AT4G19600.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021768 Genomic DNA. Translation: CAB40377.1. Sequence problems.
AL161551 Genomic DNA. Translation: CAB78962.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84203.1.
AK117509 mRNA. Translation: BAC42172.1.
BT029301 mRNA. Translation: ABK32115.1.
PIRiT06153.
RefSeqiNP_193695.2. NM_118080.2.
UniGeneiAt.32800.

3D structure databases

ProteinModelPortaliQ8GYM6.
SMRiQ8GYM6. Positions 32-269.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G19600.1.

PTM databases

iPTMnetiQ8GYM6.

Proteomic databases

PaxDbiQ8GYM6.
PRIDEiQ8GYM6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G19600.1; AT4G19600.1; AT4G19600.
GeneIDi827702.
GrameneiAT4G19600.1; AT4G19600.1; AT4G19600.
KEGGiath:AT4G19600.

Organism-specific databases

TAIRiAT4G19600.

Phylogenomic databases

eggNOGiKOG0834. Eukaryota.
COG5333. LUCA.
HOGENOMiHOG000220828.
InParanoidiQ8GYM6.
KOiK15188.
OMAiDFNVYHP.
PhylomeDBiQ8GYM6.

Enzyme and pathway databases

ReactomeiR-ATH-112382. Formation of RNA Pol II elongation complex.
R-ATH-674695. RNA Polymerase II Pre-transcription Events.
R-ATH-6796648. TP53 Regulates Transcription of DNA Repair Genes.

Miscellaneous databases

PROiQ8GYM6.

Gene expression databases

GenevisibleiQ8GYM6. AT.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR013763. Cyclin-like.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Arabidopsis ORF clones."
    Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.
    Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Genome-wide analysis of the cyclin family in Arabidopsis and comparative phylogenetic analysis of plant cyclin-like proteins."
    Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W., Ma H.
    Plant Physiol. 135:1084-1099(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  6. "Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks."
    Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A., Grossmann J., Gruissem W., Baginsky S.
    Plant Physiol. 150:889-903(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-396, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiCCT14_ARATH
AccessioniPrimary (citable) accession number: Q8GYM6
Secondary accession number(s): Q9SN70
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 1, 2003
Last modified: June 8, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.