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Protein

Probable protein phosphatase 2C 52

Gene

At4g03415

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi102Manganese 1By similarity1
Metal bindingi102Manganese 2By similarity1
Metal bindingi103Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi317Manganese 2By similarity1
Metal bindingi363Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • protein dephosphorylation Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-70895 Branched-chain amino acid catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 52 (EC:3.1.3.16)
Short name:
AtPP2C52
Gene namesi
Ordered Locus Names:At4g03415
ORF Names:F9H3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G03415
TAIRilocus:504955459 AT4G03415

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679761 – 468Probable protein phosphatase 2C 52Add BLAST468

Proteomic databases

PaxDbiQ8GY60
PRIDEiQ8GY60

PTM databases

iPTMnetiQ8GY60

Expressioni

Gene expression databases

ExpressionAtlasiQ8GY60 differential

Interactioni

Protein-protein interaction databases

BioGridi13221, 1 interactor
STRINGi3702.AT4G03415.1

Structurei

3D structure databases

ProteinModelPortaliQ8GY60
SMRiQ8GY60
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 372PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST306

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233897
InParanoidiQ8GY60
OMAiINQDAMV
OrthoDBiEOG09360CO1
PhylomeDBiQ8GY60

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 2 hits
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8GY60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGCVSTSSK STCSSWSNGE KPVRRPYLGI GCCVSKRAKR TFSDHIVSLQ
60 70 80 90 100
NLTSIPNRIT SSSKSRSSCI FTQQGRKGIN QDAMIVWEDF MSEDVTFCGV
110 120 130 140 150
FDGHGPYGHL VARKVRDTLP VKLQFFFQTL QSKQNCSKGT RFRRNSSKSA
160 170 180 190 200
VQEAVKEGSD EDKLKGLWGE AFLKSFKAMD KELRSHPNLD CFCSGSTGVT
210 220 230 240 250
ILKQGSNLFM GNIGDSRAIL GSKDSNDSMV ATQLTVDLKP DLPREAERIK
260 270 280 290 300
RCKGRVFAME DEPEVPRVWL PYDDAPGLAM ARAFGDFCLK EYGVISVPEF
310 320 330 340 350
THRVLTDRDQ FIVLASDGVW DVLSNEEVVD IVASATSRAS AARTLVNSAA
360 370 380 390 400
REWKLKYPTS KMDDCAVVCL FLDGKMDSES DYDEQGFSSA TNAVESDDGQ
410 420 430 440 450
RSEPCLQRNF TVRSSSDQEN ETYGNVNTET DAEDEKTVGD QNWLGLQGVT
460
RVNSLVQLPR FSEEKSKT
Length:468
Mass (Da):51,851
Last modified:March 1, 2003 - v1
Checksum:iFFE03E4F6DA93D05
GO

Sequence cautioni

The sequence AF071527 differs from that shown. Reason: Frameshift at position 215.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF071527 Genomic DNA No translation available.
CP002687 Genomic DNA Translation: AEE82317.1
CP002687 Genomic DNA Translation: AEE82318.1
CP002687 Genomic DNA Translation: ANM68033.1
AK117847 mRNA Translation: BAC42488.1
BT005384 mRNA Translation: AAO63448.1
RefSeqiNP_001190668.1, NM_001203739.2
NP_001329815.1, NM_001340447.1
NP_680572.4, NM_148206.5
UniGeneiAt.45457

Genome annotation databases

EnsemblPlantsiAT4G03415.1; AT4G03415.1; AT4G03415
AT4G03415.2; AT4G03415.2; AT4G03415
AT4G03415.3; AT4G03415.3; AT4G03415
GeneIDi827930
GrameneiAT4G03415.1; AT4G03415.1; AT4G03415
AT4G03415.2; AT4G03415.2; AT4G03415
AT4G03415.3; AT4G03415.3; AT4G03415
KEGGiath:AT4G03415

Similar proteinsi

Entry informationi

Entry nameiP2C52_ARATH
AccessioniPrimary (citable) accession number: Q8GY60
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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