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Protein

Probable protein phosphatase 2C 52

Gene

At4g03415

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi102Manganese 1By similarity1
Metal bindingi102Manganese 2By similarity1
Metal bindingi103Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi317Manganese 2By similarity1
Metal bindingi363Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • protein dephosphorylation Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 52 (EC:3.1.3.16)
Short name:
AtPP2C52
Gene namesi
Ordered Locus Names:At4g03415
ORF Names:F9H3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G03415.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679761 – 468Probable protein phosphatase 2C 52Add BLAST468

Proteomic databases

PaxDbiQ8GY60.

PTM databases

iPTMnetiQ8GY60.

Expressioni

Gene expression databases

ExpressionAtlasiQ8GY60. baseline and differential.

Interactioni

Protein-protein interaction databases

BioGridi13221. 1 interactor.
STRINGi3702.AT4G03415.1.

Structurei

3D structure databases

ProteinModelPortaliQ8GY60.
SMRiQ8GY60.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 372PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST306

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233897.
InParanoidiQ8GY60.
OMAiDGEAVNN.
OrthoDBiEOG09360CO1.
PhylomeDBiQ8GY60.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8GY60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGCVSTSSK STCSSWSNGE KPVRRPYLGI GCCVSKRAKR TFSDHIVSLQ
60 70 80 90 100
NLTSIPNRIT SSSKSRSSCI FTQQGRKGIN QDAMIVWEDF MSEDVTFCGV
110 120 130 140 150
FDGHGPYGHL VARKVRDTLP VKLQFFFQTL QSKQNCSKGT RFRRNSSKSA
160 170 180 190 200
VQEAVKEGSD EDKLKGLWGE AFLKSFKAMD KELRSHPNLD CFCSGSTGVT
210 220 230 240 250
ILKQGSNLFM GNIGDSRAIL GSKDSNDSMV ATQLTVDLKP DLPREAERIK
260 270 280 290 300
RCKGRVFAME DEPEVPRVWL PYDDAPGLAM ARAFGDFCLK EYGVISVPEF
310 320 330 340 350
THRVLTDRDQ FIVLASDGVW DVLSNEEVVD IVASATSRAS AARTLVNSAA
360 370 380 390 400
REWKLKYPTS KMDDCAVVCL FLDGKMDSES DYDEQGFSSA TNAVESDDGQ
410 420 430 440 450
RSEPCLQRNF TVRSSSDQEN ETYGNVNTET DAEDEKTVGD QNWLGLQGVT
460
RVNSLVQLPR FSEEKSKT
Length:468
Mass (Da):51,851
Last modified:March 1, 2003 - v1
Checksum:iFFE03E4F6DA93D05
GO

Sequence cautioni

The sequence AF071527 differs from that shown. Reason: Frameshift at position 215.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF071527 Genomic DNA. No translation available.
CP002687 Genomic DNA. Translation: AEE82317.1.
CP002687 Genomic DNA. Translation: AEE82318.1.
AK117847 mRNA. Translation: BAC42488.1.
BT005384 mRNA. Translation: AAO63448.1.
RefSeqiNP_001190668.1. NM_001203739.2.
NP_680572.4. NM_148206.5.
UniGeneiAt.45457.

Genome annotation databases

EnsemblPlantsiAT4G03415.1; AT4G03415.1; AT4G03415.
AT4G03415.2; AT4G03415.2; AT4G03415.
GeneIDi827930.
GrameneiAT4G03415.1; AT4G03415.1; AT4G03415.
AT4G03415.2; AT4G03415.2; AT4G03415.
KEGGiath:AT4G03415.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF071527 Genomic DNA. No translation available.
CP002687 Genomic DNA. Translation: AEE82317.1.
CP002687 Genomic DNA. Translation: AEE82318.1.
AK117847 mRNA. Translation: BAC42488.1.
BT005384 mRNA. Translation: AAO63448.1.
RefSeqiNP_001190668.1. NM_001203739.2.
NP_680572.4. NM_148206.5.
UniGeneiAt.45457.

3D structure databases

ProteinModelPortaliQ8GY60.
SMRiQ8GY60.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi13221. 1 interactor.
STRINGi3702.AT4G03415.1.

PTM databases

iPTMnetiQ8GY60.

Proteomic databases

PaxDbiQ8GY60.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G03415.1; AT4G03415.1; AT4G03415.
AT4G03415.2; AT4G03415.2; AT4G03415.
GeneIDi827930.
GrameneiAT4G03415.1; AT4G03415.1; AT4G03415.
AT4G03415.2; AT4G03415.2; AT4G03415.
KEGGiath:AT4G03415.

Organism-specific databases

TAIRiAT4G03415.

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233897.
InParanoidiQ8GY60.
OMAiDGEAVNN.
OrthoDBiEOG09360CO1.
PhylomeDBiQ8GY60.

Miscellaneous databases

PROiQ8GY60.

Gene expression databases

ExpressionAtlasiQ8GY60. baseline and differential.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C52_ARATH
AccessioniPrimary (citable) accession number: Q8GY60
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.