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Protein

Glutamine synthetase cytosolic isozyme 1-5

Gene

GLN1-5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processNitrogen fixation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-210455 Astrocytic Glutamate-Glutamine Uptake And Metabolism
R-ATH-70614 Amino acid synthesis and interconversion (transamination)

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase cytosolic isozyme 1-5 (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase GLN1;5
Short name:
GLN1;5
Gene namesi
Name:GLN1-5
Ordered Locus Names:At1g48470
ORF Names:T1N15.8, T1N15_7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G48470
TAIRilocus:2198080 AT1G48470

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002398212 – 353Glutamine synthetase cytosolic isozyme 1-5Add BLAST352

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylthreonineCombined sources1
Modified residuei3PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ8GXW5
PRIDEiQ8GXW5

PTM databases

iPTMnetiQ8GXW5

Expressioni

Tissue specificityi

Not expressed in roots.1 Publication

Gene expression databases

ExpressionAtlasiQ8GXW5 baseline and differential
GenevisibleiQ8GXW5 AT

Interactioni

Subunit structurei

Homooctamer.By similarity

Protein-protein interaction databases

BioGridi26493, 2 interactors
IntActiQ8GXW5, 1 interactor
STRINGi3702.AT1G48470.1

Structurei

3D structure databases

ProteinModelPortaliQ8GXW5
SMRiQ8GXW5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Phylogenomic databases

eggNOGiKOG0683 Eukaryota
COG0174 LUCA
HOGENOMiHOG000061500
InParanoidiQ8GXW5
KOiK01915
OMAiTKLPKWN
OrthoDBiEOG09360EP2
PhylomeDBiQ8GXW5

Family and domain databases

Gene3Di3.10.20.70, 1 hit
InterProiView protein in InterPro
IPR008147 Gln_synt_b-grasp
IPR036651 Gln_synt_N
IPR014746 Gln_synth/guanido_kin_cat_dom
IPR008146 Gln_synth_cat_dom
IPR027303 Gln_synth_gly_rich_site
IPR027302 Gln_synth_N_conserv_site
PfamiView protein in Pfam
PF00120 Gln-synt_C, 1 hit
PF03951 Gln-synt_N, 1 hit
SMARTiView protein in SMART
SM01230 Gln-synt_C, 1 hit
SUPFAMiSSF54368 SSF54368, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00180 GLNA_1, 1 hit
PS00181 GLNA_ATP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8GXW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSPLSDLLN LDLSDTKKII AEYIWIGGSG MDIRSKARTL PGPVSNPTKL
60 70 80 90 100
PKWNYDGSST DQAAGDDSEV ILYPQAIFKD PFRKGNNILV MCDAYRPAGD
110 120 130 140 150
PIPTNNRHKA VKIFDHPNVK AEEPWFGIEQ EYTLLKKDVK WPLGWPLGGF
160 170 180 190 200
PGPQGPYYCA VGADKAFGRD IVDAHYKACL YSGLSIGGAN GEVMPGQWEF
210 220 230 240 250
QISPTVGIGA GDQLWVARYI LERITEICGV IVSFDPKPIQ GDWNGAAAHT
260 270 280 290 300
NFSTKSMRKD GGLDLIKEAI KKLEVKHKQH IAAYGEGNER RLTGKHETAD
310 320 330 340 350
INTFSWGVAD RGASVRVGRD TEKEGKGYFE DRRPSSNMDP YLVTSMIAET

TIL
Length:353
Mass (Da):38,907
Last modified:March 1, 2003 - v1
Checksum:i79C4A429340C697B
GO

Sequence cautioni

The sequence AAF79695 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti46N → D in AAM62764 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020889 Genomic DNA Translation: AAF79695.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE32297.1
AK118005 mRNA Translation: BAC42638.1
BT006245 mRNA Translation: AAP12894.1
AY085540 mRNA Translation: AAM62764.1
RefSeqiNP_175280.1, NM_103743.3
UniGeneiAt.28083

Genome annotation databases

EnsemblPlantsiAT1G48470.1; AT1G48470.1; AT1G48470
GeneIDi841268
GrameneiAT1G48470.1; AT1G48470.1; AT1G48470
KEGGiath:AT1G48470

Similar proteinsi

Entry informationi

Entry nameiGLN15_ARATH
AccessioniPrimary (citable) accession number: Q8GXW5
Secondary accession number(s): Q8LEA1, Q9LP78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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