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Q8GXW1

- RGL2_ARATH

UniProt

Q8GXW1 - RGL2_ARATH

Protein

DELLA protein RGL2

Gene

RGL2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 2 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Acts as a major GA-response repressor of seed germination, including seed thermoinhibition. Promotes the biosynthesis of abscisic acid (ABA), especially in seed coats to maintain seed dormancy. Delays flowering and adult leaf production. Also regulates the floral development, petal, stamen and anther development, by repressing the continued growth of floral organs. Its activity is probably regulated by other phytohormones such as auxin and ethylene. Involved in the regulation of seed dormancy and germination, including glucose-induced delay of seed germination. Promotes salt tolerance. Acts as a repressor of positive regulators of trichome initiation. Required during the flagellin-derived peptide flg22-mediated growth inhibition. Contributes to the susceptibility to the biotrophic pathogen P.syringae pv. tomato and to the resistance to the necrotrophic pathogens B.cinerea A.brassicicola, probably by repressing the SA-defense pathway and preventing cell death. Prevents stress-induced reactive oxygen species (ROS) accumulation (e.g. salt stress) by acting on the ROS scavenging system, and delays ROS-induced cell death, thus promoting stress tolerance.17 Publications

    GO - Molecular functioni

    1. protein binding Source: UniProtKB
    2. sequence-specific DNA binding transcription factor activity Source: TAIR

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. defense response Source: UniProtKB-KW
    3. flower development Source: UniProtKB-KW
    4. gibberellic acid mediated signaling pathway Source: TAIR
    5. hyperosmotic salinity response Source: TAIR
    6. jasmonic acid mediated signaling pathway Source: TAIR
    7. negative regulation of gibberellic acid mediated signaling pathway Source: TAIR
    8. negative regulation of seed germination Source: TAIR
    9. regulation of reactive oxygen species metabolic process Source: TAIR
    10. regulation of seed dormancy process Source: TAIR
    11. regulation of seed germination Source: TAIR
    12. response to abscisic acid Source: TAIR
    13. response to ethylene Source: TAIR
    14. response to gibberellin Source: TAIR
    15. response to salt stress Source: TAIR
    16. salicylic acid mediated signaling pathway Source: TAIR
    17. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein, Repressor

    Keywords - Biological processi

    Differentiation, Flowering, Gibberellin signaling pathway, Plant defense, Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DELLA protein RGL2
    Alternative name(s):
    GRAS family protein 15
    Short name:
    AtGRAS-15
    RGA-like protein 2
    Scarecrow-like protein 19
    Short name:
    AtSCL19
    Gene namesi
    Name:RGL2
    Synonyms:SCL19
    Ordered Locus Names:At3g03450
    ORF Names:T21P5.13
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G03450.

    Subcellular locationi

    Nucleus 1 Publication

    GO - Cellular componenti

    1. nucleus Source: TAIR

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Disruption phenotypei

    Higher germination rate in the presence of glucose and at supraoptimal temperature conditions. Rga, gai, rgl1, rgl2 and rgl3 pentuple mutant displays constitutive GA responses even in the absence of GA treatment.3 Publications

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi44 – 485Missing: Induces a resistance to GA-mediated degradation.
    Mutagenesisi52 – 521Y → A or E: Induces a resistance to GA-mediated degradation. 2 Publications
    Mutagenesisi52 – 521Y → F: Normal GA-mediated degradation. 2 Publications
    Mutagenesisi57 – 571S → D: No effect. 1 Publication
    Mutagenesisi86 – 861S → D: No effect. 1 Publication
    Mutagenesisi89 – 891Y → A or E: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi89 – 891Y → F: Normal GA-mediated degradation. 1 Publication
    Mutagenesisi103 – 1031S → D: No effect. 1 Publication
    Mutagenesisi212 – 2121S → D: No effect. 1 Publication
    Mutagenesisi223 – 2231Y → A or E: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi223 – 2231Y → F: Normal GA-mediated degradation. 1 Publication
    Mutagenesisi259 – 2591Y → A: Induces a partial resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi271 – 2711T → C: Induces a decrease to GA-mediated degradation. 1 Publication
    Mutagenesisi271 – 2711T → E: Null mutant; induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi319 – 3191T → C: No effect. 1 Publication
    Mutagenesisi319 – 3191T → E: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi381 – 3811S → D: No effect. 1 Publication
    Mutagenesisi411 – 4111T → C: No effect. 1 Publication
    Mutagenesisi411 – 4111T → E: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi435 – 4351Y → A or E: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi435 – 4351Y → F: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi436 – 4361S → D: No effect. 1 Publication
    Mutagenesisi437 – 4371S → D: No effect. 1 Publication
    Mutagenesisi441 – 4411S → C: No effect. 1 Publication
    Mutagenesisi441 – 4411S → D: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi456 – 4561S → D: No effect. 1 Publication
    Mutagenesisi481 – 4811T → E: No effect. 1 Publication
    Mutagenesisi501 – 5011S → D: No effect. 1 Publication
    Mutagenesisi508 – 5081S → D: No effect. 1 Publication
    Mutagenesisi535 – 5351T → C: No effect. 1 Publication
    Mutagenesisi535 – 5351T → E: Induces a resistance to GA-mediated degradation. 1 Publication
    Mutagenesisi542 – 5421S → C: No effect. 1 Publication
    Mutagenesisi542 – 5421S → D: Induces a resistance to GA-mediated degradation. 1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 547547DELLA protein RGL2PRO_0000132237Add
    BLAST

    Post-translational modificationi

    Phosphorylated. Phosphorylation on Tyr residues is required for proteasome-mediated degradation in response to gibberellic acid (GA). Dephosphorylation may be prerequisite for its degradation by the proteasome.2 Publications
    Ubiquitinated Probable. Upon GA application or seed imbibation, it is ubiquitinated by the SCF(GID2) complex, leading to its subsequent degradation.Curated

    Keywords - PTMi

    Phosphoprotein, Ubl conjugation

    Proteomic databases

    PRIDEiQ8GXW1.

    Expressioni

    Tissue specificityi

    Predominantly expressed in germinating seeds, flowers and siliques. Only detectable in the inflorescence, with high levels in young flower buds and significant levels in siliques. In imbibed seeds, it is restricted to seed coats, elongating regions of pre-emergent and recently emerged radicles, endosperm (especially micropylar endosperm), and embryonic axis. Not expressed in leaves, bolting stems or roots.5 Publications

    Inductioni

    Up-regulated transiently following seed imbibition to decline rapidly as germination proceeds; this induction is delayed at supraoptimal temperature conditions (e.g. 34 degrees Celsius). Accumulates in seed coats of dormant seeds where germination does not occur after imbibition. Increased levels upon abscisic acid (ABA) treatment. Down-regulated by norflurazon (NF), an ABA biosynthesis inhibitor. Induced by stress such as glucose, salt or mannitol treatment.7 Publications

    Gene expression databases

    GenevestigatoriQ8GXW1.

    Interactioni

    Subunit structurei

    Interacts directly with the GID2/SLY1 component of the SCF(GID2) complex. Interacts (via N-terminus) with GID1A, GID1B and GID1C (via N-terminus). Binds to bHLH transcription factors such as PIF1, PIF4, PIF6 and SPT. Interacts with the BOI proteins BOI, BRG1, BRG2 and BRG3.5 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    GID1AQ9MAA73EBI-963665,EBI-963597
    GID1CQ940G63EBI-963665,EBI-963794

    Protein-protein interaction databases

    BioGridi6584. 10 interactions.
    DIPiDIP-37661N.
    IntActiQ8GXW1. 3 interactions.
    MINTiMINT-8069272.
    STRINGi3702.AT3G03450.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8GXW1.
    SMRiQ8GXW1. Positions 44-106.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi44 – 485DELLA motif
    Motifi66 – 705LEXLE motif
    Motifi87 – 915VHYNP motif
    Motifi286 – 2905VHIID
    Motifi385 – 3895LXXLL motif

    Domaini

    The DELLA motif is required for its GA-induced degradation but not for the interaction with GID2.

    Sequence similaritiesi

    Belongs to the GRAS family. DELLA subfamily.Curated

    Phylogenomic databases

    eggNOGiNOG243696.
    HOGENOMiHOG000238577.
    InParanoidiQ8GXW1.
    KOiK14494.
    OMAiMLSELNN.
    PhylomeDBiQ8GXW1.

    Family and domain databases

    InterProiIPR021914. TF_DELLA_N.
    IPR005202. TF_GRAS.
    [Graphical view]
    PfamiPF12041. DELLA. 1 hit.
    PF03514. GRAS. 1 hit.
    [Graphical view]
    PROSITEiPS50985. GRAS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8GXW1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKRGYGETWD PPPKPLPASR SGEGPSMADK KKADDDNNNS NMDDELLAVL    50
    GYKVRSSEMA EVAQKLEQLE MVLSNDDVGS TVLNDSVHYN PSDLSNWVES 100
    MLSELNNPAS SDLDTTRSCV DRSEYDLRAI PGLSAFPKEE EVFDEEASSK 150
    RIRLGSWCES SDESTRSVVL VDSQETGVRL VHALVACAEA IHQENLNLAD 200
    ALVKRVGTLA GSQAGAMGKV ATYFAQALAR RIYRDYTAET DVCAAVNPSF 250
    EEVLEMHFYE SCPYLKFAHF TANQAILEAV TTARRVHVID LGLNQGMQWP 300
    ALMQALALRP GGPPSFRLTG IGPPQTENSD SLQQLGWKLA QFAQNMGVEF 350
    EFKGLAAESL SDLEPEMFET RPESETLVVN SVFELHRLLA RSGSIEKLLN 400
    TVKAIKPSIV TVVEQEANHN GIVFLDRFNE ALHYYSSLFD SLEDSYSLPS 450
    QDRVMSEVYL GRQILNVVAA EGSDRVERHE TAAQWRIRMK SAGFDPIHLG 500
    SSAFKQASML LSLYATGDGY RVEENDGCLM IGWQTRPLIT TSAWKLA 547
    Length:547
    Mass (Da):60,494
    Last modified:November 22, 2005 - v2
    Checksum:iC4D18D5951D95634
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti210 – 2101A → T in BAC42642. (PubMed:11910074)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009895 Genomic DNA. Translation: AAF01590.1.
    CP002686 Genomic DNA. Translation: AEE73945.1.
    AK118009 mRNA. Translation: BAC42642.1.
    RefSeqiNP_186995.1. NM_111216.2.
    UniGeneiAt.18489.
    At.67027.

    Genome annotation databases

    EnsemblPlantsiAT3G03450.1; AT3G03450.1; AT3G03450.
    GeneIDi821251.
    KEGGiath:AT3G03450.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    Kiss of life - Issue 137 of April 2012

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009895 Genomic DNA. Translation: AAF01590.1 .
    CP002686 Genomic DNA. Translation: AEE73945.1 .
    AK118009 mRNA. Translation: BAC42642.1 .
    RefSeqi NP_186995.1. NM_111216.2.
    UniGenei At.18489.
    At.67027.

    3D structure databases

    ProteinModelPortali Q8GXW1.
    SMRi Q8GXW1. Positions 44-106.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 6584. 10 interactions.
    DIPi DIP-37661N.
    IntActi Q8GXW1. 3 interactions.
    MINTi MINT-8069272.
    STRINGi 3702.AT3G03450.1-P.

    Proteomic databases

    PRIDEi Q8GXW1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G03450.1 ; AT3G03450.1 ; AT3G03450 .
    GeneIDi 821251.
    KEGGi ath:AT3G03450.

    Organism-specific databases

    GeneFarmi 4240. 427.
    TAIRi AT3G03450.

    Phylogenomic databases

    eggNOGi NOG243696.
    HOGENOMi HOG000238577.
    InParanoidi Q8GXW1.
    KOi K14494.
    OMAi MLSELNN.
    PhylomeDBi Q8GXW1.

    Gene expression databases

    Genevestigatori Q8GXW1.

    Family and domain databases

    InterProi IPR021914. TF_DELLA_N.
    IPR005202. TF_GRAS.
    [Graphical view ]
    Pfami PF12041. DELLA. 1 hit.
    PF03514. GRAS. 1 hit.
    [Graphical view ]
    PROSITEi PS50985. GRAS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "The GRAS gene family in Arabidopsis: sequence characterization and basic expression analysis of the SCARECROW-LIKE genes."
      Pysh L.D., Wysocka-Diller J.W., Camilleri C., Bouchez D., Benfey P.N.
      Plant J. 18:111-119(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION.
    5. "Gibberellin regulates Arabidopsis seed germination via RGL2, a GAI/RGA-like gene whose expression is up-regulated following imbibition."
      Lee S., Cheng H., King K.E., Wang W., He Y., Hussain A., Lo J., Harberd N.P., Peng J.
      Genes Dev. 16:646-658(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, TISSUE SPECIFICITY, INDUCTION.
    6. "Auxin promotes Arabidopsis root growth by modulating gibberellin response."
      Fu X., Harberd N.P.
      Nature 421:740-743(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    7. "Ethylene regulates Arabidopsis development via the modulation of DELLA protein growth repressor function."
      Achard P., Vriezen W.H., Van Der Straeten D., Harberd N.P.
      Plant Cell 15:2816-2825(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    8. "Gibberellin regulates Arabidopsis floral development via suppression of DELLA protein function."
      Cheng H., Qin L., Lee S., Fu X., Richards D.E., Cao D., Luo D., Harberd N.P., Peng J.
      Development 131:1055-1064(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    9. "Della proteins and gibberellin-regulated seed germination and floral development in Arabidopsis."
      Tyler L., Thomas S.G., Hu J., Dill A., Alonso J.M., Ecker J.R., Sun T.-P.
      Plant Physiol. 135:1008-1019(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROBABLE UBIQUITINATION, DEGRADATION, INTERACTION WITH GID2.
    10. "Floral homeotic genes are targets of gibberellin signaling in flower development."
      Yu H., Ito T., Zhao Y., Peng J., Kumar P., Meyerowitz E.M.
      Proc. Natl. Acad. Sci. U.S.A. 101:7827-7832(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    11. "Loss of function of four DELLA genes leads to light- and gibberellin-independent seed germination in Arabidopsis."
      Cao D., Hussain A., Cheng H., Peng J.
      Planta 223:105-113(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    12. "Identification of the conserved serine/threonine residues important for gibberellin-sensitivity of Arabidopsis RGL2 protein."
      Hussain A., Cao D., Cheng H., Wen Z., Peng J.
      Plant J. 44:88-99(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROBABLE UBIQUITINATION, DEGRADATION, PHOSPHORYLATION, MUTAGENESIS OF 48-ASP--ALA-52; TYR-52; SER-57; SER-86; SER-103; SER-212; THR-271; THR-319; SER-381; THR-411; SER-436; SER-437; SER-441; SER-456; THR-481; SER-501; SER-508; THR-535 AND SER-542.
    13. "DELLA-mediated cotyledon expansion breaks coat-imposed seed dormancy."
      Penfield S., Gilday A.D., Halliday K.J., Graham I.A.
      Curr. Biol. 16:2366-2370(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    14. "Phytohormone signalling pathways interact with sugars during seed germination and seedling development."
      Yuan K., Wysocka-Diller J.
      J. Exp. Bot. 57:3359-3367(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY GLUCOSE.
    15. Cited for: INTERACTION WITH GID1A; GID1B AND GID1C.
    16. "Integration of plant responses to environmentally activated phytohormonal signals."
      Achard P., Cheng H., De Grauwe L., Decat J., Schoutteten H., Moritz T., Van Der Straeten D., Peng J., Harberd N.P.
      Science 311:91-94(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    17. "Seed germination of GA-insensitive sleepy1 mutants does not require RGL2 protein disappearance in Arabidopsis."
      Ariizumi T., Steber C.M.
      Plant Cell 19:791-804(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INDUCTION.
    18. "Genetic and molecular regulation by DELLA proteins of trichome development in Arabidopsis."
      Gan Y., Yu H., Peng J., Broun P.
      Plant Physiol. 145:1031-1042(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    19. "Identification of conserved tyrosine residues important for gibberellin sensitivity of Arabidopsis RGL2 protein."
      Hussain A., Cao D., Peng J.
      Planta 226:475-483(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION OF TYR RESIDUES, MUTAGENESIS OF TYR-52; TYR-89; TYR-223; TYR-259 AND TYR-435.
    20. "DELLAs control plant immune responses by modulating the balance of jasmonic acid and salicylic acid signaling."
      Navarro L., Bari R., Achard P., Lison P., Nemri A., Harberd N.P., Jones J.D.G.
      Curr. Biol. 18:650-655(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
      Strain: cv. Landsberg erecta.
    21. "Plant DELLAs restrain growth and promote survival of adversity by reducing the levels of reactive oxygen species."
      Achard P., Renou J.-P., Berthome R., Harberd N.P., Genschik P.
      Curr. Biol. 18:656-660(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INDUCTION BY SALT AND MANNITOL TREATMENT.
    22. "The gibberellic acid signaling repressor RGL2 inhibits Arabidopsis seed germination by stimulating abscisic acid synthesis and ABI5 activity."
      Piskurewicz U., Jikumaru Y., Kinoshita N., Nambara E., Kamiya Y., Lopez-Molina L.
      Plant Cell 20:2729-2745(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INDUCTION BY ABA, TISSUE SPECIFICITY.
    23. "High temperature-induced abscisic acid biosynthesis and its role in the inhibition of gibberellin action in Arabidopsis seeds."
      Toh S., Imamura A., Watanabe A., Nakabayashi K., Okamoto M., Jikumaru Y., Hanada A., Aso Y., Ishiyama K., Tamura N., Iuchi S., Kobayashi M., Yamaguchi S., Kamiya Y., Nambara E., Kawakami N.
      Plant Physiol. 146:1368-1385(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY IMBIBITION.
    24. "Biochemical insights on degradation of Arabidopsis DELLA proteins gained from a cell-free assay system."
      Wang F., Zhu D., Huang X., Li S., Gong Y., Yao Q., Fu X., Fan L.-M., Deng X.W.
      Plant Cell 21:2378-2390(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: DEGRADATION BY PROTEASOME.
    25. "Differential expression and affinities of Arabidopsis gibberellin receptors can explain variation in phenotypes of multiple knock-out mutants."
      Suzuki H., Park S.-H., Okubo K., Kitamura J., Ueguchi-Tanaka M., Iuchi S., Katoh E., Kobayashi M., Yamaguchi I., Matsuoka M., Asami T., Nakajima M.
      Plant J. 60:48-55(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY, INTERACTION WITH GID1A; GID1B AND GID1C.
    26. "Transcriptional diversification and functional conservation between DELLA proteins in Arabidopsis."
      Gallego-Bartolome J., Minguet E.G., Marin J.A., Prat S., Blazquez M.A., Alabadi D.
      Mol. Biol. Evol. 27:1247-1256(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, INTERACTION WITH PIF1; PIF4; PIF6 AND SPT.
      Strain: cv. Landsberg erecta.
    27. "A seed coat bedding assay shows that RGL2-dependent release of abscisic acid by the endosperm controls embryo growth in Arabidopsis dormant seeds."
      Lee K.P., Piskurewicz U., Tureckova V., Strnad M., Lopez-Molina L.
      Proc. Natl. Acad. Sci. U.S.A. 107:19108-19113(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INDUCTION DURING IMBIBITION, TISSUE SPECIFICITY.
    28. "DELLA proteins and their interacting RING Finger proteins repress gibberellin responses by binding to the promoters of a subset of gibberellin-responsive genes in Arabidopsis."
      Park J., Nguyen K.T., Park E., Jeon J.S., Choi G.
      Plant Cell 25:927-943(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH BOI; BRG1; BRG2 AND BRG3, DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiRGL2_ARATH
    AccessioniPrimary (citable) accession number: Q8GXW1
    Secondary accession number(s): Q9SRP9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 86 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3