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Protein

Thioredoxin-like protein CXXS2

Gene

CXXS2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Possesses low disulfide reductase activity, but efficient protein disulfide isomerase activity. Does not possess deglutathionylation activity.1 Publication

Caution

Lacks the conserved cysteine (here Ser-77), present in the redox-active center, which is one of the conserved features of the thioredoxin family.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin-like protein CXXS2
Short name:
AtCXXS2
Alternative name(s):
Mono-cysteine thioredoxin 2
Gene namesi
Name:CXXS2
Ordered Locus Names:At2g40790
ORF Names:T7D17.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G40790
TAIRilocus:2064854 AT2G40790

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003945471 – 154Thioredoxin-like protein CXXS2Add BLAST154

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei31PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8GXV2
PRIDEiQ8GXV2

Expressioni

Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

ExpressionAtlasiQ8GXV2 baseline and differential
GenevisibleiQ8GXV2 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G40790.1

Structurei

3D structure databases

ProteinModelPortaliQ8GXV2
SMRiQ8GXV2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 148ThioredoxinPROSITE-ProRule annotationAdd BLAST126

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi5 – 21Cys-richAdd BLAST17

Sequence similaritiesi

Belongs to the thioredoxin family.Curated

Phylogenomic databases

eggNOGiKOG0907 Eukaryota
COG0526 LUCA
HOGENOMiHOG000292977
InParanoidiQ8GXV2
KOiK03671
OMAiCTRIPCC
OrthoDBiEOG09360XJ5
PhylomeDBiQ8GXV2

Family and domain databases

InterProiView protein in InterPro
IPR005746 Thioredoxin
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain
PANTHERiPTHR10438 PTHR10438, 1 hit
PfamiView protein in Pfam
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS51352 THIOREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8GXV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNHCTRIPC CKKVCSCICC CNRRNKTQAR SQKGSYFIKG KVHPVSRMEK
60 70 80 90 100
WEEKITEANS HGKILVVNFK ASWCLPSKTI LPIYQELAST YTSMIFVTID
110 120 130 140 150
VEELAEFSHE WNVDATPTVV FLKDGRQMDK LVGGDAAELQ KKTAAAANLL

LRQS
Length:154
Mass (Da):17,314
Last modified:March 1, 2003 - v1
Checksum:iA9B0DB455E890401
GO

Sequence cautioni

The sequence AAC49350 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35639 Genomic DNA Translation: AAC49350.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC09879.1
CP002685 Genomic DNA Translation: ANM62990.1
AK118023 mRNA Translation: BAC42656.1
BT003671 mRNA Translation: AAO39899.1
PIRiH84833
RefSeqiNP_001318396.1, NM_001336864.1
NP_181611.2, NM_129642.4
UniGeneiAt.46001
At.53090

Genome annotation databases

EnsemblPlantsiAT2G40790.1; AT2G40790.1; AT2G40790
AT2G40790.2; AT2G40790.2; AT2G40790
GeneIDi818676
GrameneiAT2G40790.1; AT2G40790.1; AT2G40790
AT2G40790.2; AT2G40790.2; AT2G40790
KEGGiath:AT2G40790

Similar proteinsi

Entry informationi

Entry nameiCXXS2_ARATH
AccessioniPrimary (citable) accession number: Q8GXV2
Secondary accession number(s): Q38878
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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