Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein NRT1/ PTR FAMILY 7.2

Gene

NPF7.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Low-affinity nitrate transporter. Involved in nitrate removal from xylem sap. Not involved in oligopeptides transport.1 Publication

GO - Molecular functioni

  • nitrate transmembrane transporter activity Source: TAIR
  • symporter activity Source: UniProtKB-KW

GO - Biological processi

  • nitrate assimilation Source: UniProtKB-KW
  • response to cadmium ion Source: TAIR
  • response to nitrate Source: TAIR

Keywordsi

Biological processNitrate assimilation, Symport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-427975 Proton/oligopeptide cotransporters
R-ATH-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NRT1/ PTR FAMILY 7.2
Short name:
AtNPF7.2
Alternative name(s):
Nitrate transporter 1.8
Gene namesi
Name:NPF7.2
Synonyms:NRT1.8
Ordered Locus Names:At4g21680
ORF Names:F17L22.140
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G21680
TAIRilocus:2119058 AT4G21680

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 52HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Transmembranei187 – 207HelicalSequence analysisAdd BLAST21
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Transmembranei343 – 363HelicalSequence analysisAdd BLAST21
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Transmembranei423 – 443HelicalSequence analysisAdd BLAST21
Transmembranei464 – 484HelicalSequence analysisAdd BLAST21
Transmembranei504 – 524HelicalSequence analysisAdd BLAST21
Transmembranei548 – 568HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

No visible phenotype. Higher nitrate concentration in xylem sap and increased cadmium sensitivity. A greater proportion of nitrate accumulates in shoots under cadmium stress.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003999811 – 589Protein NRT1/ PTR FAMILY 7.2Add BLAST589

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei102PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8GXN2
PRIDEiQ8GXN2

Expressioni

Tissue specificityi

Expressed in xylem parenchyma cells within the vasculature. Expressed in siliques and flowers. Higher expression in shoots than in roots.2 Publications

Inductioni

Up-regulated by cadmium and nitrate.1 Publication

Gene expression databases

ExpressionAtlasiQ8GXN2 baseline and differential
GenevisibleiQ8GXN2 AT

Interactioni

Protein-protein interaction databases

BioGridi13544, 25 interactors
STRINGi3702.AT4G21680.1

Structurei

3D structure databases

ProteinModelPortaliQ8GXN2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi455 – 460Poly-Ser6
Compositional biasi585 – 588Poly-Glu4

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1237 Eukaryota
COG3104 LUCA
HOGENOMiHOG000237400
InParanoidiQ8GXN2
OMAiCEPERIK
OrthoDBiEOG093605FC
PhylomeDBiQ8GXN2

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR000109 POT_fam
PANTHERiPTHR11654 PTHR11654, 1 hit
PfamiView protein in Pfam
PF00854 PTR2, 1 hit
SUPFAMiSSF103473 SSF103473, 2 hits

Sequencei

Sequence statusi: Complete.

Q8GXN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQKVRQFEV CTQDGSVDRH GNPAIRANTG KWLTAILILV NQGLATLAFF
60 70 80 90 100
GVGVNLVLFL TRVMGQDNAE AANNVSKWTG TVYIFSLLGA FLSDSYWGRY
110 120 130 140 150
KTCAIFQASF VAGLMMLSLS TGALLLEPSG CGVEDSPCKP HSTFKTVLFY
160 170 180 190 200
LSVYLIALGY GGYQPNIATF GADQFDAEDS VEGHSKIAFF SYFYLALNLG
210 220 230 240 250
SLFSNTVLGY FEDQGEWPLG FWASAGSAFA GLVLFLIGTP KYRHFTPRES
260 270 280 290 300
PWSRFCQVLV AATRKAKIDV HHEELNLYDS ETQYTGDKKI LHTKGFRFLD
310 320 330 340 350
RAAIVTPDDE AEKVESGSKY DPWRLCSVTQ VEEVKCVLRL LPIWLCTILY
360 370 380 390 400
SVVFTQMASL FVVQGAAMKT NIKNFRIPAS SMSSFDILSV AFFIFAYRRF
410 420 430 440 450
LDPLFARLNK TERNKGLTEL QRMGIGLVIA IMAMISAGIV EIHRLKNKEP
460 470 480 490 500
ESATSISSSS TLSIFWQVPQ YMLIGASEVF MYVGQLEFFN SQAPTGLKSF
510 520 530 540 550
ASALCMASIS LGNYVSSLLV SIVMKISTTD DVHGWIPENL NKGHLERFYF
560 570 580
LLAGLTAADF VVYLICAKWY KYIKSEASFS ESVTEEEEV
Length:589
Mass (Da):65,507
Last modified:November 2, 2010 - v2
Checksum:i0FEF4CF5162067F0
GO

Sequence cautioni

The sequence CAB36812 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB81275 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti389S → N in BAC42767 (PubMed:11910074).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035527 Genomic DNA Translation: CAB36812.1 Sequence problems.
AL161555 Genomic DNA Translation: CAB81275.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE84489.1
AK118142 mRNA Translation: BAC42767.1
PIRiT05843
RefSeqiNP_193899.2, NM_118288.4
UniGeneiAt.2700
At.32611

Genome annotation databases

EnsemblPlantsiAT4G21680.1; AT4G21680.1; AT4G21680
GeneIDi828255
GrameneiAT4G21680.1; AT4G21680.1; AT4G21680
KEGGiath:AT4G21680

Similar proteinsi

Entry informationi

Entry nameiPTR47_ARATH
AccessioniPrimary (citable) accession number: Q8GXN2
Secondary accession number(s): Q9SVS9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: November 2, 2010
Last modified: April 25, 2018
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health