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Protein

Sugar transporter ERD6-like 14

Gene

At4g04750

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sugar transporter.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-428790. Facilitative Na+-independent glucose transporters.

Names & Taxonomyi

Protein namesi
Recommended name:
Sugar transporter ERD6-like 14
Gene namesi
Ordered Locus Names:At4g04750
ORF Names:T4B21.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G04750.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei36 – 5621Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei72 – 9221Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei103 – 12321Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei134 – 15421Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei166 – 18621Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei189 – 20921Helical; Name=6Sequence analysisAdd
BLAST
Transmembranei271 – 29121Helical; Name=7Sequence analysisAdd
BLAST
Transmembranei309 – 32921Helical; Name=8Sequence analysisAdd
BLAST
Transmembranei337 – 35721Helical; Name=9Sequence analysisAdd
BLAST
Transmembranei370 – 39021Helical; Name=10Sequence analysisAdd
BLAST
Transmembranei410 – 43021Helical; Name=11Sequence analysisAdd
BLAST
Transmembranei436 – 45621Helical; Name=12Sequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 482482Sugar transporter ERD6-like 14PRO_0000259864Add
BLAST

Proteomic databases

PaxDbiQ8GXK5.
PRIDEiQ8GXK5.

Expressioni

Gene expression databases

GenevisibleiQ8GXK5. AT.

Interactioni

Protein-protein interaction databases

BioGridi11122. 26 interactions.
STRINGi3702.AT4G04750.1.

Structurei

3D structure databases

ProteinModelPortaliQ8GXK5.
SMRiQ8GXK5. Positions 33-471.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202868.
InParanoidiQ8GXK5.
OMAiVYTIWIT.
OrthoDBiEOG09360A9A.
PhylomeDBiQ8GXK5.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8GXK5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAEESLLPSH TEDVSASPNK SSSLLSEISN ASTRPFVLAF TVGSCGALSF
60 70 80 90 100
GCIVGYTAPT QSSIMKDLNL SIADFSFFGS ILTVGLILGA LICGKLADLV
110 120 130 140 150
GRVYTIWITN ILVLIGWLAI AFAKDVRLLD LGRLLQGISV GISSYLGPIY
160 170 180 190 200
ISELAPRNLR GAASSLMQLF VGVGLSAFYA LGTAVAWRSL AILGSIPSLV
210 220 230 240 250
VLPLLFFIPE SPRWLAKVGR EKEVEGVLLS LRGAKSDVSD EAATILEYTK
260 270 280 290 300
HVEQQDIDSR GFFKLFQRKY ALPLTIGVVL ISMPQLGGLN GYTFYTDTIF
310 320 330 340 350
TSTGVSSDIG FILTSIVQMT GGVLGVLLVD ISGRRSLLLF SQAGMFLGCL
360 370 380 390 400
ATAISFFLQK NNCWETGTPI MALISVMVYF GSYGLGMGPI PWIIASEIYP
410 420 430 440 450
VDVKGAAGTV CNLVTSISSW LVTYSFNFLL QWSSTGTFMM FATVMGLGFV
460 470 480
FTAKLVPETK GKSLEEIQSA FTDSTSEDST IF
Length:482
Mass (Da):51,677
Last modified:November 28, 2006 - v2
Checksum:i4BC40F375F7F8239
GO
Isoform 2 (identifier: Q8GXK5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     304-482: GVSSDIGFIL...DSTSEDSTIF → DDWRRFRCFA...GNRNTNNGSH

Note: Incomplete sequence. No experimental confirmation available.
Show »
Length:359
Mass (Da):38,958
Checksum:i13EDACDEF632FC15
GO

Sequence cautioni

The sequence AAD03450 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAB80840 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti269 – 2691K → R in BAC42813 (PubMed:11910074).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei304 – 482179GVSSD…DSTIF → DDWRRFRCFACGYIRKTFSP TVFSSWNVLGLSSNSHFILL AEEQLLGNRNTNNGSH in isoform 2. CuratedVSP_021552Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF118223 Genomic DNA. Translation: AAD03450.1. Sequence problems.
AL161501 Genomic DNA. Translation: CAB80840.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE82421.1.
AK118190 mRNA. Translation: BAC42813.1.
PIRiG85059.
RefSeqiNP_192384.2. NM_116713.2. [Q8GXK5-1]
UniGeneiAt.33970.

Genome annotation databases

EnsemblPlantsiAT4G04750.1; AT4G04750.1; AT4G04750. [Q8GXK5-1]
GeneIDi825811.
KEGGiath:AT4G04750.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF118223 Genomic DNA. Translation: AAD03450.1. Sequence problems.
AL161501 Genomic DNA. Translation: CAB80840.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE82421.1.
AK118190 mRNA. Translation: BAC42813.1.
PIRiG85059.
RefSeqiNP_192384.2. NM_116713.2. [Q8GXK5-1]
UniGeneiAt.33970.

3D structure databases

ProteinModelPortaliQ8GXK5.
SMRiQ8GXK5. Positions 33-471.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi11122. 26 interactions.
STRINGi3702.AT4G04750.1.

Proteomic databases

PaxDbiQ8GXK5.
PRIDEiQ8GXK5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G04750.1; AT4G04750.1; AT4G04750. [Q8GXK5-1]
GeneIDi825811.
KEGGiath:AT4G04750.

Organism-specific databases

TAIRiAT4G04750.

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202868.
InParanoidiQ8GXK5.
OMAiVYTIWIT.
OrthoDBiEOG09360A9A.
PhylomeDBiQ8GXK5.

Enzyme and pathway databases

ReactomeiR-ATH-428790. Facilitative Na+-independent glucose transporters.

Miscellaneous databases

PROiQ8GXK5.

Gene expression databases

GenevisibleiQ8GXK5. AT.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEDL14_ARATH
AccessioniPrimary (citable) accession number: Q8GXK5
Secondary accession number(s): Q9M100, Q9ZS99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: September 7, 2016
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.