Q8GX84 (C3H1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc finger CCCH domain-containing protein 1
Short name=AtC3H1

Gene names

Ordered Locus Names:	At1g01350
ORF Names:	F6F3.14

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 C3H1-type zinc finger. Contains 1 RING-type zinc finger.
Sequence caution	The sequence AAF97335.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Domain	Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Zinc finger CCCH domain-containing protein 1		PRO_0000371963
Regions
	Zinc finger	200 – 228	29	C3H1-type
	Zinc finger	277 – 315	39	RING-type
Experimental info
	Sequence conflict	232	1	P → S in BAC42988. Ref.3
	Sequence conflict	304	1	H → R in BAC42988. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q8GX84 [UniParc]. Last modified May 5, 2009. Version 2. Checksum: 86E6DE6EDF1A3E04	FASTA	343	38,710
	10 20 30 40 50 60 MSDSGEPKPS QQEEPLPQPA AQETQSQQVC TFFKKPTKSK NIRKRTIDAD EEDGDSKSES 70 80 90 100 110 120 SILQNLKKVA KPDSKLYFSS GPSKSSTTTS GAPERSVFHY DSSKEIQVQN DSGATATLET 130 140 150 160 170 180 ETDFNQDARA IRERVLKKAD EALKGNKKKA SDEKLYKGIH GYTDHKAGFR REQTISSEKA 190 200 210 220 230 240 GGSHGPLRAS AHIRVSARFD YQPDICKDYK ETGYCGYGDS CKFLHDRGDY KPGWQIEKEW 250 260 270 280 290 300 EEAEKVRKRN KAMGVEDEDD EADKDSDEDE NALPFACFIC REPFVDPVVT KCKHYFCEHC 310 320 330 340 ALKHHTKNKK CFVCNQPTMG IFNAAHEIKK RMAEERSKAE QGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Functional annotation of a full-length Arabidopsis cDNA collection." Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K. Science 296:141-145(2002) [PubMed: 11910074] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice." Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C. BMC Genomics 9:44-44(2008) [PubMed: 18221561] [Abstract] Cited for: NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC023628 Genomic DNA. Translation: AAF97335.1. Sequence problems. CP002684 Genomic DNA. Translation: AEE27275.1. AK118376 mRNA. Translation: BAC42988.1.
IPI	IPI00537158.
PIR	G86143.
RefSeq	NP_171642.2. NM_100017.2.
UniGene	At.48142.
3D structure databases
HSSP	HSSP built from PDB template 2CSY based on UniProtKB Q8IZP6.
ProteinModelPortal	Q8GX84.
SMR	Q8GX84. Positions 200-228, 265-337.
ModBase	Search...
Proteomic databases
PRIDE	Q8GX84.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G01350.1; AT1G01350.1; AT1G01350.
GeneID	838964.
GenomeReviews	Gene locus AT1G01350 in contig CT485782_GR.
KEGG	ath:AT1G01350.
Organism-specific databases
TAIR	At1g01350.
Phylogenomic databases
eggNOG	KOG1813.
GeneTree	EPGT00050000008927.
HOGENOM	HBG738163.
InParanoid	Q8GX84.
PhylomeDB	Q8GX84.
ProtClustDB	CLSN2686864.
Gene expression databases
Genevestigator	Q8GX84.
Family and domain databases
InterPro	IPR018957. Znf_C3HC4_RING-type. IPR000571. Znf_CCCH. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit.
KO	K13127.
Pfam	PF00097. zf-C3HC4. 1 hit. PF00642. zf-CCCH. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. SM00356. ZnF_C3H1. 1 hit. [Graphical view]
PROSITE	PS50103. ZF_C3H1. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3H1_ARATH

Accession

Primary (citable) accession number: Q8GX84
Secondary accession number(s): Q9LNI9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	December 14, 2011
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program