Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptidyl-tRNA hydrolase, chloroplastic

Gene

At1g18440

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.By similarity

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolase, chloroplastic (EC:3.1.1.29)
Alternative name(s):
C-PTH
Gene namesi
Ordered Locus Names:At1g18440
ORF Names:F15H18.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G18440
TAIRilocus:2014134 AT1G18440

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 55ChloroplastSequence analysisAdd BLAST55
ChainiPRO_000028052756 – 288Peptidyl-tRNA hydrolase, chloroplasticAdd BLAST233

Proteomic databases

PaxDbiQ8GW64
PRIDEiQ8GW64

Expressioni

Gene expression databases

ExpressionAtlasiQ8GW64 baseline and differential
GenevisibleiQ8GW64 AT

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

BioGridi23663, 1 interactor
STRINGi3702.AT1G18440.1

Structurei

3D structure databases

ProteinModelPortaliQ8GW64
SMRiQ8GW64
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi52 – 88Ser-richAdd BLAST37

Sequence similaritiesi

Belongs to the PTH family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG2255 Eukaryota
COG0193 LUCA
HOGENOMiHOG000004797
InParanoidiQ8GW64
KOiK01056
OMAiSQWLGTR
OrthoDBiEOG09360L5D
PhylomeDBiQ8GW64

Family and domain databases

Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8GW64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAVAFPAKI ANLSFPSNCC SLFFRSPATF LSPALPCRKL TKGIRGLEGL
60 70 80 90 100
MSQCLSSSSQ SLSFSSNSFS SQPESELLQA LPSSKPKSPP LQLPWLIVGL
110 120 130 140 150
GNPGKKYQGT RHNVGFEMVD ALADAEGISM NTVNFKALFG KGVIGNIPIM
160 170 180 190 200
LAKPQTFMNL SGESVGQIVS FYKIPLKQVL VVYDDLDLPF GKLRLLPKGG
210 220 230 240 250
HGGHNGMRSI IDRLKGSRDF PRLRIGIGRP PGKMDTANFV LRQFNRQEQE
260 270 280
ELDHTFQTGL EAIRILLLEG FNKSATFVNT RKSMEQLS
Length:288
Mass (Da):31,562
Last modified:March 20, 2007 - v2
Checksum:i9CD118CA2915DD0F
GO

Sequence cautioni

The sequence AAF25998 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At1g18440 and At1g18450.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti159N → D in BAC43630 (PubMed:11910074).Curated1
Sequence conflicti159N → D in AAO63348 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013354 Genomic DNA Translation: AAF25998.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE29714.1
AK119054 mRNA Translation: BAC43630.1
BT005284 mRNA Translation: AAO63348.1
PIRiC86318
RefSeqiNP_173279.2, NM_101701.4
UniGeneiAt.22357

Genome annotation databases

EnsemblPlantsiAT1G18440.1; AT1G18440.1; AT1G18440
GeneIDi838424
GrameneiAT1G18440.1; AT1G18440.1; AT1G18440
KEGGiath:AT1G18440

Similar proteinsi

Entry informationi

Entry nameiPTHC_ARATH
AccessioniPrimary (citable) accession number: Q8GW64
Secondary accession number(s): Q9LPQ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: May 23, 2018
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health