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Protein

Tubby-like F-box protein 2

Gene

TULP2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • phosphatidylinositol binding Source: GO_Central
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • regulation of transcription, DNA-templated Source: TAIR
  • response to fungus Source: TAIR
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Tubby-like F-box protein 2
Short name:
AtTLP2
Gene namesi
Name:TULP2
Ordered Locus Names:At2g18280
ORF Names:T30D6.21
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G18280.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: TAIR
  • nucleus Source: TAIR
  • plasma membrane Source: TAIR
  • plastid Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Tubby-like F-box protein 2PRO_0000272230Add
BLAST

Proteomic databases

PaxDbiQ8GVE5.
PRIDEiQ8GVE5.

PTM databases

iPTMnetiQ8GVE5.

Expressioni

Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

ExpressionAtlasiQ8GVE5. baseline and differential.
GenevisibleiQ8GVE5. AT.

Interactioni

Protein-protein interaction databases

BioGridi1701. 3 interactions.
STRINGi3702.AT2G18280.1.

Structurei

3D structure databases

ProteinModelPortaliQ8GVE5.
SMRiQ8GVE5. Positions 111-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini46 – 10156F-boxAdd
BLAST

Sequence similaritiesi

Belongs to the TUB family.Curated
Contains 1 F-box domain.Curated

Phylogenomic databases

eggNOGiKOG2502. Eukaryota.
ENOG410XQFT. LUCA.
HOGENOMiHOG000238161.
InParanoidiQ8GVE5.
OMAiYRVATIS.
PhylomeDBiQ8GVE5.

Family and domain databases

Gene3Di3.20.90.10. 1 hit.
InterProiIPR001810. F-box_dom.
IPR000007. Tubby_C.
IPR025659. Tubby_C-like.
IPR018066. Tubby_C_CS.
[Graphical view]
PfamiPF00646. F-box. 1 hit.
PF01167. Tub. 1 hit.
[Graphical view]
PRINTSiPR01573. SUPERTUBBY.
SUPFAMiSSF54518. SSF54518. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiPS01200. TUB_1. 1 hit.
PS01201. TUB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8GVE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLKSILRDL KEVRDGLGGI SKRSWSKSSH IAPDQTTPPL DNIPQSPWAS
60 70 80 90 100
LPPELLHDII WRVEESETAW PARAAVVSCA SVCKSWRGIT MEIVRIPEQC
110 120 130 140 150
GKLTFPISLK QPGPRDSPIQ CFIKRNRATA TYILYYGLMP SETENDKLLL
160 170 180 190 200
AARRIRRATC TDFIISLSAK NFSRSSSTYV GKLRSGFLGT KFTIYDNQTA
210 220 230 240 250
SSTAQAQPNR RLHPKQAAPK LPTNSSTVGN ITYELNVLRT RGPRRMHCAM
260 270 280 290 300
DSIPLSSVIA EPSVVQGIEE EVSSSPSPKG ETITTDKEIP DNSPSLRDQP
310 320 330 340 350
LVLKNKSPRW HEQLQCWCLN FKGRVTVASV KNFQLVAEID ASLDAPPEEH
360 370 380 390
ERVILQFGKI GKDIFTMDYR YPLSAFQAFA ICISSFDTKP ACEG
Length:394
Mass (Da):43,878
Last modified:March 1, 2003 - v1
Checksum:i2BBA39F8666AEDC0
GO

Sequence cautioni

The sequence AAD15508.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti358 – 3581G → V in AAP40448 (PubMed:14593172).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY045773 mRNA. Translation: AAK98801.1.
AC006439 Genomic DNA. Translation: AAD15508.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC06748.1.
CP002685 Genomic DNA. Translation: AEC06749.1.
BT008627 mRNA. Translation: AAP40448.1.
BT025314 mRNA. Translation: ABF47130.1.
PIRiE84562.
RefSeqiNP_001031369.1. NM_001036292.2.
NP_849975.1. NM_179644.2.
UniGeneiAt.21504.
At.63472.
At.75572.

Genome annotation databases

EnsemblPlantsiAT2G18280.1; AT2G18280.1; AT2G18280.
AT2G18280.2; AT2G18280.2; AT2G18280.
GeneIDi816344.
GrameneiAT2G18280.1; AT2G18280.1; AT2G18280.
AT2G18280.2; AT2G18280.2; AT2G18280.
KEGGiath:AT2G18280.

Cross-referencesi

Web resourcesi

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY045773 mRNA. Translation: AAK98801.1.
AC006439 Genomic DNA. Translation: AAD15508.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC06748.1.
CP002685 Genomic DNA. Translation: AEC06749.1.
BT008627 mRNA. Translation: AAP40448.1.
BT025314 mRNA. Translation: ABF47130.1.
PIRiE84562.
RefSeqiNP_001031369.1. NM_001036292.2.
NP_849975.1. NM_179644.2.
UniGeneiAt.21504.
At.63472.
At.75572.

3D structure databases

ProteinModelPortaliQ8GVE5.
SMRiQ8GVE5. Positions 111-393.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi1701. 3 interactions.
STRINGi3702.AT2G18280.1.

PTM databases

iPTMnetiQ8GVE5.

Proteomic databases

PaxDbiQ8GVE5.
PRIDEiQ8GVE5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G18280.1; AT2G18280.1; AT2G18280.
AT2G18280.2; AT2G18280.2; AT2G18280.
GeneIDi816344.
GrameneiAT2G18280.1; AT2G18280.1; AT2G18280.
AT2G18280.2; AT2G18280.2; AT2G18280.
KEGGiath:AT2G18280.

Organism-specific databases

TAIRiAT2G18280.

Phylogenomic databases

eggNOGiKOG2502. Eukaryota.
ENOG410XQFT. LUCA.
HOGENOMiHOG000238161.
InParanoidiQ8GVE5.
OMAiYRVATIS.
PhylomeDBiQ8GVE5.

Miscellaneous databases

PROiQ8GVE5.

Gene expression databases

ExpressionAtlasiQ8GVE5. baseline and differential.
GenevisibleiQ8GVE5. AT.

Family and domain databases

Gene3Di3.20.90.10. 1 hit.
InterProiIPR001810. F-box_dom.
IPR000007. Tubby_C.
IPR025659. Tubby_C-like.
IPR018066. Tubby_C_CS.
[Graphical view]
PfamiPF00646. F-box. 1 hit.
PF01167. Tub. 1 hit.
[Graphical view]
PRINTSiPR01573. SUPERTUBBY.
SUPFAMiSSF54518. SSF54518. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiPS01200. TUB_1. 1 hit.
PS01201. TUB_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analyses of the Arabidopsis TUBBY-like protein gene family."
    Lai C.-P., Lee C.-L., Chen P.-H., Wu S.-H., Yang C.-C., Shaw J.-F.
    Plant Physiol. 134:1586-1597(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, NOMENCLATURE.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Arabidopsis ORF clones."
    Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.

Entry informationi

Entry nameiTLP2_ARATH
AccessioniPrimary (citable) accession number: Q8GVE5
Secondary accession number(s): Q7Y213, Q9ZPW1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: March 1, 2003
Last modified: February 17, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.