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Protein

Heat shock 70 kDa protein 9, mitochondrial

Gene

HSP70-9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity).By similarity

GO - Molecular functioni

  • ATP binding Source: TAIR
  • zinc ion binding Source: TAIR

GO - Biological processi

  • protein folding Source: InterPro
  • response to cadmium ion Source: TAIR
  • response to cytokinin Source: TAIR
  • response to salt stress Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock 70 kDa protein 9, mitochondrial
Alternative name(s):
Heat shock protein 70-9
Short name:
AtHsp70-9
Mitochondrial heat shock protein 70-1
Short name:
mtHsc70-1
Gene namesi
Name:HSP70-9
Synonyms:MTHSC70-1
Ordered Locus Names:At4g37910
ORF Names:F20D10.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G37910.

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: TAIR
  • mitochondrion Source: TAIR
  • vacuolar membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 5252MitochondrionSequence analysisAdd
BLAST
Chaini53 – 682630Heat shock 70 kDa protein 9, mitochondrialPRO_0000415428Add
BLAST

Proteomic databases

PaxDbiQ8GUM2.
PRIDEiQ8GUM2.

PTM databases

iPTMnetiQ8GUM2.
SwissPalmiQ8GUM2.

Expressioni

Gene expression databases

GenevisibleiQ8GUM2. AT.

Interactioni

Protein-protein interaction databases

BioGridi15228. 1 interaction.
IntActiQ8GUM2. 1 interaction.
MINTiMINT-8385635.
STRINGi3702.AT4G37910.1.

Structurei

3D structure databases

ProteinModelPortaliQ8GUM2.
SMRiQ8GUM2. Positions 54-644.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0102. Eukaryota.
COG0443. LUCA.
HOGENOMiHOG000228135.
InParanoidiQ8GUM2.
KOiK04043.
OMAiYLARPFC.
OrthoDBiEOG093604Y4.
PhylomeDBiQ8GUM2.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8GUM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASVALLRSF RRREVQMASV SAFKSVSANG KNSMFGKLGY LARPFCSRPV
60 70 80 90 100
GNDVIGIDLG TTNSCVSVME GKTARVIENA EGSRTTPSVV AMNQKGELLV
110 120 130 140 150
GTPAKRQAVT NPTNTIFGSK RLIGRRFDDP QTQKEMKMVP YKIVKAPNGD
160 170 180 190 200
AWVEANGQKF SPSQIGANVL TKMKETAEAY LGKSINKAVV TVPAYFNDAQ
210 220 230 240 250
RQATKDAGKI AGLDVQRIIN EPTAAALSYG MNNKEGVIAV FDLGGGTFDV
260 270 280 290 300
SILEISSGVF EVKATNGDTF LGGEDFDNTL LEYLVNEFKR SDNIDLTKDN
310 320 330 340 350
LALQRLREAA EKAKIELSST TQTEINLPFI TADASGAKHL NITLTRSKFE
360 370 380 390 400
GLVGKLIERT RSPCQNCLKD AGVTIKEVDE VLLVGGMTRV PKVQEIVSEI
410 420 430 440 450
FGKSPCKGVN PDEAVAMGAA IQGGILRGDV KDLLLLDVVP LSLGIETLGA
460 470 480 490 500
VFTKLIPRNT TIPTKKSQVF STAADNQMQV GIKVLQGERE MAADNKVLGE
510 520 530 540 550
FDLVGIPPAP RGMPQIEVTF DIDANGITTV SAKDKATGKE QNITIRSSGG
560 570 580 590 600
LSDDEINRMV KEAELNAQKD QEKKQLIDLR NSADTTIYSV EKSLSEYREK
610 620 630 640 650
IPAEIASEIE TAVSDLRTAM AGEDVEDIKA KVEAANKAVS KIGEHMSKGS
660 670 680
GSSGSDGSSG EGTSGTEQTP EAEFEEASGS RK
Length:682
Mass (Da):73,075
Last modified:March 1, 2003 - v1
Checksum:iBE8EC435202E7234
GO

Sequence cautioni

The sequence CAB37531 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAB80456 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti414 – 4141A → V in BAD94381 (Ref. 4) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035538 Genomic DNA. Translation: CAB37531.1. Different initiation.
AL161592 Genomic DNA. Translation: CAB80456.1. Different initiation.
CP002687 Genomic DNA. Translation: AEE86852.1.
BT002390 mRNA. Translation: AAO00750.1.
BT008430 mRNA. Translation: AAP37789.1.
AK221937 mRNA. Translation: BAD94381.1.
PIRiT05618.
RefSeqiNP_195504.2. NM_119952.3.
UniGeneiAt.2734.

Genome annotation databases

EnsemblPlantsiAT4G37910.1; AT4G37910.1; AT4G37910.
GeneIDi829947.
GrameneiAT4G37910.1; AT4G37910.1; AT4G37910.
KEGGiath:AT4G37910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035538 Genomic DNA. Translation: CAB37531.1. Different initiation.
AL161592 Genomic DNA. Translation: CAB80456.1. Different initiation.
CP002687 Genomic DNA. Translation: AEE86852.1.
BT002390 mRNA. Translation: AAO00750.1.
BT008430 mRNA. Translation: AAP37789.1.
AK221937 mRNA. Translation: BAD94381.1.
PIRiT05618.
RefSeqiNP_195504.2. NM_119952.3.
UniGeneiAt.2734.

3D structure databases

ProteinModelPortaliQ8GUM2.
SMRiQ8GUM2. Positions 54-644.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi15228. 1 interaction.
IntActiQ8GUM2. 1 interaction.
MINTiMINT-8385635.
STRINGi3702.AT4G37910.1.

PTM databases

iPTMnetiQ8GUM2.
SwissPalmiQ8GUM2.

Proteomic databases

PaxDbiQ8GUM2.
PRIDEiQ8GUM2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G37910.1; AT4G37910.1; AT4G37910.
GeneIDi829947.
GrameneiAT4G37910.1; AT4G37910.1; AT4G37910.
KEGGiath:AT4G37910.

Organism-specific databases

TAIRiAT4G37910.

Phylogenomic databases

eggNOGiKOG0102. Eukaryota.
COG0443. LUCA.
HOGENOMiHOG000228135.
InParanoidiQ8GUM2.
KOiK04043.
OMAiYLARPFC.
OrthoDBiEOG093604Y4.
PhylomeDBiQ8GUM2.

Miscellaneous databases

PROiQ8GUM2.

Gene expression databases

GenevisibleiQ8GUM2. AT.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSP7I_ARATH
AccessioniPrimary (citable) accession number: Q8GUM2
Secondary accession number(s): Q56WU4, Q9SZJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.