Q8GU20 (Q8GU20_RAUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Strictosidine-O-beta-D-glucosidase EMBL CAC83098.1

Gene names

Name:

sgr1 EMBL CAC83098.1

Organism

Rauvolfia serpentina (Serpentwood) (Devilpepper) EMBL CAC83098.1

Taxonomic identifier

4060 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Gentianales › Apocynaceae › Rauvolfioideae › Vinceae › Rauvolfia

Protein attributes

Sequence length	532 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 1 family. RuleBase RU003690

Ontologies

Keywords
Technical term	3D-structure PDB 2JF7 PDB 2JF6
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8GU20 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: FC65D93E90212710	FASTA	532	60,881
	10 20 30 40 50 60 MDNTQAEPLV VAIVPKPNAS TEHTNSHLIP VTRSKIVVHR RDFPQDFIFG AGGSAYQCEG 70 80 90 100 110 120 AYNEGNRGPS IWDTFTQRSP AKISDGSNGN QAINCYHMYK EDIKIMKQTG LESYRFSISW 130 140 150 160 170 180 SRVLPGGRLA AGVNKDGVKF YHDFIDELLA NGIKPSVTLF HWDLPQALED EYGGFLSHRI 190 200 210 220 230 240 VDDFCEYAEF CFWEFGDKIK YWTTFNEPHT FAVNGYALGE FAPGRGGKGD EGDPAIEPYV 250 260 270 280 290 300 VTHNILLAHK AAVEEYRNKF QKCQEGEIGI VLNSMWMEPL SDVQADIDAQ KRALDFMLGW 310 320 330 340 350 360 FLEPLTTGDY PKSMRELVKG RLPKFSADDS EKLKGCYDFI GMNYYTATYV TNAVKSNSEK 370 380 390 400 410 420 LSYETDDQVT KTFERNQKPI GHALYGGWQH VVPWGLYKLL VYTKETYHVP VLYVTESGMV 430 440 450 460 470 480 EENKTKILLS EARRDAERTD YHQKHLASVR DAIDDGVNVK GYFVWSFFDN FEWNLGYICR 490 500 510 520 530 YGIIHVDYKS FERYPKESAI WYKNFIAGKS TTSPAKRRRE EAQVELVKRQ KT

References

[1]	"Molecular cloning and functional bacterial expression of strictosidine glucosidase from Rauvolfia serpentina cell suspension cultures." Gerasimenko I., Sheludko Y., Stoeckigt J. Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Molecular architecture of strictosidine glucosidase: the gateway to the biosynthesis of the monoterpenoid indole alkaloid family." Barleben L., Panjikar S., Ruppert M., Koepke J., Stockigt J. Plant Cell 19:2886-2897(2007) [PubMed: 17890378] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.48 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AJ302044 mRNA. Translation: CAC83098.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2JF6	X-ray	2.82	A/B	1-532	[»]
2JF7	X-ray	2.48	A/B	1-532	[»]

ProteinModelPortal

Q8GU20.

SMR

Q8GU20. Positions 37-507.

ModBase

Search...

Protein family/group databases

CAZy

GH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Enzyme and pathway databases

BRENDA

3.2.1.105. 257570.

Family and domain databases

InterPro

IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

Gene3D

G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.

PANTHER

PTHR10353. Glyco_hydro_1. 1 hit.

Pfam

PF00232. Glyco_hydro_1. 1 hit.
[Graphical view]

PRINTS

PR00131. GLHYDRLASE1.

SUPFAM

SSF51445. Glyco_hydro_cat. 1 hit.

PROSITE

PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8GU20_RAUSE

Accession

Primary (citable) accession number: Q8GU20

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 31, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)