ID   Q8GTB9_WHEAT            Unreviewed;       222 AA.
AC   Q8GTB9;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   08-NOV-2023, entry version 91.
DE   RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE            EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
GN   Name=gstf4 {ECO:0000313|EMBL:CAD29477.1};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EMBL:CAD29477.1};
RN   [1] {ECO:0000313|EMBL:CAD29477.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=10-day-old shoot {ECO:0000313|EMBL:CAD29477.1};
RA   Cummins I.;
RT   "Cloning, regulation and characterization of a family of phi class
RT   glutathione transferases from wheat.";
RL   Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=glutathione + RX = a halide anion + an S-substituted
CC         glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925,
CC         ChEBI:CHEBI:90779; EC=2.5.1.18;
CC         Evidence={ECO:0000256|ARBA:ARBA00000710};
CC   -!- SIMILARITY: Belongs to the GST superfamily. Phi family.
CC       {ECO:0000256|ARBA:ARBA00010128}.
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DR   EMBL; AJ440793; CAD29477.1; -; mRNA.
DR   AlphaFoldDB; Q8GTB9; -.
DR   BRENDA; 2.5.1.18; 6500.
DR   ExpressionAtlas; Q8GTB9; baseline and differential.
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   CDD; cd03187; GST_C_Phi; 1.
DR   CDD; cd03053; GST_N_Phi; 1.
DR   Gene3D; 1.20.1050.10; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR034347; GST_Phi_C.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR43900; GLUTATHIONE S-TRANSFERASE RHO; 1.
DR   PANTHER; PTHR43900:SF13; GLUTATHIONE TRANSFERASE; 1.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SFLD; SFLDG01154; Main.5:_Phi-like; 1.
DR   SFLD; SFLDG00358; Main_(cytGST); 1.
DR   SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   2: Evidence at transcript level;
KW   Transferase {ECO:0000313|EMBL:CAD29477.1}.
FT   DOMAIN          2..83
FT                   /note="GST N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50404"
FT   DOMAIN          88..214
FT                   /note="GST C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50405"
SQ   SEQUENCE   222 AA;  24937 MW;  4C36554F907ED347 CRC64;
     MEPMKVYGWA VSPWMARVLV SLEEAGADYE LVPMSRNGGD HRRPEHLARN PFGEIPVLEY
     GGLTLYQSRA IARHILRKHK PGLLGAGSLE ESAMVDVWVD VDAHHLEPVL KPIVWNCIIN
     PFVGRDVDQG LVDESVEKLK KLLEVYEARL SSNKYLAGDF VSFADLTHFS FMRYFMATEH
     AVVLDAYPHV KAWWKALLAR PSVKKVIAGM PPDFGFGSGR IP
//