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Protein
Submitted name:

Alpha-amylase A

Gene

amyA

Organism
Halothermothrix orenii
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi44 – 441Calcium 1Combined sources
Metal bindingi46 – 461Calcium 1Combined sources
Metal bindingi48 – 481Calcium 1Combined sources
Metal bindingi50 – 501Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi52 – 521Calcium 1Combined sources
Metal bindingi65 – 651Calcium 2Combined sources
Metal bindingi67 – 671Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi70 – 701Calcium 2Combined sources
Metal bindingi73 – 731Calcium 2Combined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylase AImported
Gene namesi
Name:amyAImported
OrganismiHalothermothrix oreniiImported
Taxonomic identifieri31909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaHalanaerobialesHalanaerobiaceaeHalothermothrix

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 515490Sequence analysisPRO_5004307870Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi373903.Hore_14740.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WZAX-ray1.60A28-515[»]
ProteinModelPortaliQ8GPL8.
SMRiQ8GPL8. Positions 28-515.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8GPL8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 428393AamyInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105CG3. Bacteria.
COG0366. LUCA.

Family and domain databases

Gene3Di3.20.20.80. 2 hits.
InterProiIPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 2 hits.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8GPL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKRLSFFM FVTLLVFISV FPVYANDFEK HGTYYEIFVR SFYDSDGDGI
60 70 80 90 100
GDLKGIIEKL DYLNDGDPET IADLGVNGIW LMPIFKSPSY HGYDVTDYYK
110 120 130 140 150
INPDYGTLED FHKLVEAAHQ RGIKVIIDLP INHTSERHPW FLKASRDKNS
160 170 180 190 200
EYRDYYVWAG PDTDTKETKL DGGRVWHYSP TGMYYGYFWS GMPDLNYNNP
210 220 230 240 250
EVQEKVIGIA KYWLKQGVDG FRLDGAMHIF PPAQYDKNFT WWEKFRQEIE
260 270 280 290 300
EVKPVYLVGE VWDISETVAP YFKYGFDSTF NFKLAEAVIA TAKAGFPFGF
310 320 330 340 350
NKKAKHIYGV YDREVGFGNY IDAPFLTNHD QNRILDQLGQ DRNKARVAAS
360 370 380 390 400
IYLTLPGNPF IYYGEEIGMR GQGPHEVIRE PFQWYNGSGE GETYWEPAMY
410 420 430 440 450
NDGFTSVEQE EKNLDSLLNH YRRLIHFRNE NPVFYTGKIE IINGGLNVVA
460 470 480 490 500
FRRYNDKRDL YVYHNLVNRP VKIKVASGNW TLLFNSGDKE ITPVEDNNKL
510
MYTIPAYTTI VLEKE
Length:515
Mass (Da):59,888
Last modified:March 1, 2003 - v1
Checksum:i2BF9FAA5FBD4E0C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF442961 Genomic DNA. Translation: AAN52525.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF442961 Genomic DNA. Translation: AAN52525.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WZAX-ray1.60A28-515[»]
ProteinModelPortaliQ8GPL8.
SMRiQ8GPL8. Positions 28-515.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi373903.Hore_14740.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105CG3. Bacteria.
COG0366. LUCA.

Miscellaneous databases

EvolutionaryTraceiQ8GPL8.

Family and domain databases

Gene3Di3.20.20.80. 2 hits.
InterProiIPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 2 hits.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8GPL8_9FIRM
AccessioniPrimary (citable) accession number: Q8GPL8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 11, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.