Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Far1

Gene

far1

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi157 – 1571ZincCombined sources
Metal bindingi160 – 1601ZincCombined sources
Metal bindingi189 – 1891ZincCombined sources
Metal bindingi195 – 1951ZincCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Far1Imported
Submitted name:
FusBImported
Submitted name:
FusB proteinImported
Submitted name:
Fusidic acid resistanceImported
Gene namesi
Name:far1Imported
Synonyms:fusBImported
Encoded oniPlasmid pUB101Imported
Plasmid pUB102Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Interactioni

Protein-protein interaction databases

DIPiDIP-60010N.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4ADNX-ray1.65A/B1-213[»]
4ADOX-ray2.30A/B1-213[»]
4E4BX-ray2.80A1-213[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR010841. Fibronectin-bd.
[Graphical view]
PfamiPF07299. FBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8GNY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTMIYPHQY NYIRSVILRL KNVYKTVNDK ETVKVIQSET YNDINEIFGH
60 70 80 90 100
IDDDIEESLK VLMNIRLSNK EIEAILNKFL EYVVPFELPS PQKLQKVFKK
110 120 130 140 150
VKKIKIPQFE EYDLKVSSFV GWNELASNRK YIIYYDEKKQ LKGLYGEISN
160 170 180 190 200
QVVKGFCTIC NKESNVSLFM KKSKTNSDGQ YVKKGDYICR DSIHCNKQLT
210
DINQFYNFID KLD
Length:213
Mass (Da):25,188
Last modified:March 1, 2003 - v1
Checksum:i4171C35EEAEA74B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY047358 Genomic DNA. Translation: AAL12234.1.
AY373761 Genomic DNA. Translation: AAN07146.1.
DQ269019 Genomic DNA. Translation: ABB82610.1.
AM292600 Genomic DNA. Translation: CAL23838.1.
RefSeqiNP_932197.1. NC_005127.1.
WP_000855537.1. NG_036179.1.
YP_009078429.1. NG_035898.1.
YP_009080429.1. NG_036179.1.

Genome annotation databases

GeneIDi2610355.
KEGGipg:2610355.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY047358 Genomic DNA. Translation: AAL12234.1.
AY373761 Genomic DNA. Translation: AAN07146.1.
DQ269019 Genomic DNA. Translation: ABB82610.1.
AM292600 Genomic DNA. Translation: CAL23838.1.
RefSeqiNP_932197.1. NC_005127.1.
WP_000855537.1. NG_036179.1.
YP_009078429.1. NG_035898.1.
YP_009080429.1. NG_036179.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4ADNX-ray1.65A/B1-213[»]
4ADOX-ray2.30A/B1-213[»]
4E4BX-ray2.80A1-213[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60010N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2610355.
KEGGipg:2610355.

Family and domain databases

InterProiIPR010841. Fibronectin-bd.
[Graphical view]
PfamiPF07299. FBP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genetic characterization of the fusidic acid and cadmium resistance determinants of Staphylococcus aureus plasmid pUB101."
    O'Brien F.G., Price C., Grubb W.B., Gustafson J.E.
    J. Antimicrob. Chemother. 50:313-321(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Plasmid: pUB101
  2. "The complete sequence of the Staphylococcus aureus beta-lactamase-fusidic acid resistance plasmid pUB101."
    O'Brien F.G., Grubb W.B., Gustafson J.E.
    Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Plasmid: pUB101
  3. "Microarray-based characterisation of a Panton-Valentine leukocidin-positive community-acquired strain of methicillin-resistant Staphylococcus aureus."
    Monecke S., Slickers P., Hotzel H., Richter-Huhn G., Pohle M., Weber S., Witte W., Ehricht R.
    Clin. Microbiol. Infect. 12:718-728(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DD04V16073Imported.
    Plasmid: pUB102
  4. "Molecular basis of fusB-mediated resistance to fusidic acid in Staphylococcus aureus."
    O'Neill A.J., Chopra I.
    Mol. Microbiol. 59:664-676(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Plasmid: pUB101
  5. "Characterization of the epidemic European fusidic acid-resistant impetigo clone of Staphylococcus aureus."
    O'neill A.J., Larsen A.R., Skov R., Henriksen A.S., Chopra I.
    J. Clin. Microbiol. 45:1505-1510(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CS6Imported.
  6. "Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling."
    Guo X., Peisker K., Backbro K., Chen Y., Koripella R.K., Mandava C.S., Sanyal S., Selmer M.
    Open Biol. 2:120016-120016(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) IN COMPLEX WITH ZINC.
  7. "Investigating the FusB:EF-G interface."
    Cox G., Edwards T.A., O'Neill A.J.
    Submitted (MAR-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ8GNY5_STAAU
AccessioniPrimary (citable) accession number: Q8GNY5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 24, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, PlasmidImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.