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Q8GNY5

- Q8GNY5_STAAU

UniProt

Q8GNY5 - Q8GNY5_STAAU

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Protein
Submitted name: Far1
Gene
far1, fusB
Organism
Staphylococcus aureus
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi157 – 1571ZincImported
Metal bindingi160 – 1601ZincImported
Metal bindingi189 – 1891ZincImported
Metal bindingi195 – 1951ZincImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

Metal-bindingImported, ZincImported

Names & Taxonomyi

Protein namesi
Submitted name:
Far1Imported
Submitted name:
FusBImported
Submitted name:
FusB proteinImported
Submitted name:
Fusidic acid resistanceImported
Gene namesi
Name:far1Imported
Synonyms:fusBImported
Encoded oniPlasmid pUB101Imported
Plasmid pUB102Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Interactioni

Protein-protein interaction databases

DIPiDIP-60010N.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4ADNX-ray1.65A/B1-213[»]
4ADOX-ray2.30A/B1-213[»]
4E4BX-ray2.80A1-213[»]

Family & Domainsi

Family and domain databases

InterProiIPR010841. Fibronectin-bd.
[Graphical view]
PfamiPF07299. FBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8GNY5-1 [UniParc]FASTAAdd to Basket

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MKTMIYPHQY NYIRSVILRL KNVYKTVNDK ETVKVIQSET YNDINEIFGH    50
IDDDIEESLK VLMNIRLSNK EIEAILNKFL EYVVPFELPS PQKLQKVFKK 100
VKKIKIPQFE EYDLKVSSFV GWNELASNRK YIIYYDEKKQ LKGLYGEISN 150
QVVKGFCTIC NKESNVSLFM KKSKTNSDGQ YVKKGDYICR DSIHCNKQLT 200
DINQFYNFID KLD 213
Length:213
Mass (Da):25,188
Last modified:March 1, 2003 - v1
Checksum:i4171C35EEAEA74B6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY047358 Genomic DNA. Translation: AAL12234.1.
AY373761 Genomic DNA. Translation: AAN07146.1.
DQ269019 Genomic DNA. Translation: ABB82610.1.
AM292600 Genomic DNA. Translation: CAL23838.1.
RefSeqiNP_932197.1. NC_005127.1.

Genome annotation databases

GeneIDi2610355.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY047358 Genomic DNA. Translation: AAL12234.1 .
AY373761 Genomic DNA. Translation: AAN07146.1 .
DQ269019 Genomic DNA. Translation: ABB82610.1 .
AM292600 Genomic DNA. Translation: CAL23838.1 .
RefSeqi NP_932197.1. NC_005127.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4ADN X-ray 1.65 A/B 1-213 [» ]
4ADO X-ray 2.30 A/B 1-213 [» ]
4E4B X-ray 2.80 A 1-213 [» ]
ModBasei Search...

Protein-protein interaction databases

DIPi DIP-60010N.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2610355.

Family and domain databases

InterProi IPR010841. Fibronectin-bd.
[Graphical view ]
Pfami PF07299. FBP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genetic characterization of the fusidic acid and cadmium resistance determinants of Staphylococcus aureus plasmid pUB101."
    O'Brien F.G., Price C., Grubb W.B., Gustafson J.E.
    J. Antimicrob. Chemother. 50:313-321(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Plasmid: pUB101
  2. "The complete sequence of the Staphylococcus aureus beta-lactamase-fusidic acid resistance plasmid pUB101."
    O'Brien F.G., Grubb W.B., Gustafson J.E.
    Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Plasmid: pUB101
  3. "Microarray-based characterisation of a Panton-Valentine leukocidin-positive community-acquired strain of methicillin-resistant Staphylococcus aureus."
    Monecke S., Slickers P., Hotzel H., Richter-Huhn G., Pohle M., Weber S., Witte W., Ehricht R.
    Clin. Microbiol. Infect. 12:718-728(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DD04V16073Imported.
    Plasmid: pUB102
  4. "Molecular basis of fusB-mediated resistance to fusidic acid in Staphylococcus aureus."
    O'Neill A.J., Chopra I.
    Mol. Microbiol. 59:664-676(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Plasmid: pUB101
  5. "Characterization of the epidemic European fusidic acid-resistant impetigo clone of Staphylococcus aureus."
    O'neill A.J., Larsen A.R., Skov R., Henriksen A.S., Chopra I.
    J. Clin. Microbiol. 45:1505-1510(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CS6Imported.
  6. "Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling."
    Guo X., Peisker K., Backbro K., Chen Y., Koripella R.K., Mandava C.S., Sanyal S., Selmer M.
    Open Biol. 2:120016-120016(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) IN COMPLEX WITH ZINC.
  7. "Investigating the FusB:EF-G interface."
    Cox G., Edwards T.A., O'Neill A.J.
    Submitted (MAR-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ8GNY5_STAAU
AccessioniPrimary (citable) accession number: Q8GNY5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, PlasmidImported

External Data

Dasty 3

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