Unreviewed, UniProtKB/TrEMBL Q8GMV7 (Q8GMV7_9ACTO)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase RuleBase RU004392V0
    EC=3.2.1.8

Gene names

Name:

xyn11A EMBL CAD48747.1

Organism

Thermopolyspora flexuosa EMBL CAD48747.1

Taxonomic identifier

103836 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Streptosporangiaceae › Thermopolyspora

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. RuleBase RU004392V0
Pathway	Glycan degradation; xylan degradation. RuleBase RU004392V0
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family. RuleBase RU003433V0

Ontologies

Keywords
Biological process	Xylan degradation RuleBase RU003433V0
Domain	Signal
Molecular function	Glycosidase RuleBase RU003433V0 Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC polysaccharide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 43	43	EMBL CAD48747.1
	Chain	44 – 344	301	endoxylanase EMBL CAD48747.1		PRO_5000068863

Sequences

	Sequence		Length	Mass (Da)
	Q8GMV7-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: E4BC3FFAD095AA02	FASTA	344	37,497
	10 20 30 40 50 60 MNEPLTITQA RRRRRLGLRR IVTSAFALAL AIAGALLPGT AHADTTITQN QTGYDNGYFY 70 80 90 100 110 120 SFWTDAPGTV SMTLHSGGSY STSWRNTGNF VAGKGWSTGG RRTVTYNASF NPSGNAYLTL 130 140 150 160 170 180 YGWTRNPLVE YYIVESWGTY RPTGTYKGTV TTDGGTYDIY ETWRYNAPSI EGTRTFQQFW 190 200 210 220 230 240 SVRQQKRTSG TITIGNHFDA WARAGMNLGS HDYQIMATEG YQSSGSSTVS ISEGGNPGNP 250 260 270 280 290 300 GNPGNPGNPG NPGNPGGGCV ATLSAGQQWS DRYNLNVSVS GSNNWTVRMD VPYPARIIAT 310 320 330 340 WNIHAQWPES QVLIARPNGN GNNWGVTIQH NGNWTWPTVT CTAN

References

[1]	"Thermostable xylanases, Xyn10A and Xyn11A, from the actinomycete Nonomuraea flexuosa: isolation of the genes and characterization of recombinant Xyn11A polypeptides produced in Trichoderma reesei." Leskinen S., Mantyla A., Fagerstrom R., Vehmaanpera J., Lantto R., Paloheimo M., Suominen P. Appl. Microbiol. Biotechnol. 67:495-505(2005) [PubMed: 15650852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Three-dimensional structures of thermophilic beta-1,4-xylanases from Chaetomium thermophilum and Nonomuraea flexuosa. Comparison of twelve xylanases in relation to their thermal stability." Hakulinen N., Turunen O., Janis J., Leisola M., Rouvinen J. Eur. J. Biochem. 270:1399-1412(2003) [PubMed: 12653995] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 44-240.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AJ508952 Genomic DNA. Translation: CAD48747.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1M4W	X-ray	2.10	A	44-240	[»]
3B5L	X-ray	1.80	B	44-237	[»]

ModBase

Search...

Protein family/group databases

CAZy

CBM2. Carbohydrate-Binding Module Family 2.
GH11. Glycoside Hydrolase Family 11.

Family and domain databases

InterPro

IPR001919. CBD_bac.
IPR012291. CBD_carb_bd.
IPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12_cat.
IPR018208. Glyco_hydro_11_AS.
[Graphical view]

Gene3D

G3DSA:2.60.40.290. CBD_carb_bd. 1 hit.
G3DSA:2.60.120.180. Glyco_hydro_11/12_cat. 1 hit.

Pfam

PF00553. CBM_2. 1 hit.
PF00457. Glyco_hydro_11. 1 hit.
[Graphical view]

PRINTS

PR00911. GLHYDRLASE11.

SMART

SM00637. CBD_II. 1 hit.
[Graphical view]

PROSITE

PS51173. CBM2. 1 hit.
PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8GMV7_9ACTO

Accession

Primary (citable) accession number: Q8GMV7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)