Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

NalP

Gene

nalP

Organism
Neisseria meningitidis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiS08.160.
TCDBi1.B.12.9.1. the autotransporter-1 (at-1) family.

Names & Taxonomyi

Protein namesi
Submitted name:
NalPImported
Gene namesi
Name:nalPImported
OrganismiNeisseria meningitidisImported
Taxonomic identifieri487 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929Sequence analysisAdd
BLAST
Chaini30 – 10831054Sequence analysisPRO_5004306165Add
BLAST

Proteomic databases

PaxDbiQ8GKS5.

Interactioni

Protein-protein interaction databases

STRINGi122586.NMB1969.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1UYNX-ray2.60X776-1083[»]
1UYOX-ray3.20X776-1083[»]
ProteinModelPortaliQ8GKS5.
SMRiQ8GKS5. Positions 785-1083.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8GKS5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini809 – 1083275Autotransporter (TC 1.B.12)InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4107ZYM. Bacteria.
COG1404. LUCA.

Family and domain databases

Gene3Di2.40.128.130. 1 hit.
3.40.50.200. 2 hits.
InterProiIPR005546. Autotransporte_beta.
IPR013425. Autotrns_rpt.
IPR000209. Peptidase_S8/S53_dom.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 4 hits.
PfamiPF03797. Autotransporter. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SMARTiSM00869. Autotransporter. 1 hit.
[Graphical view]
SUPFAMiSSF103515. SSF103515. 1 hit.
SSF52743. SSF52743. 3 hits.
TIGRFAMsiTIGR02601. autotrns_rpt. 1 hit.
PROSITEiPS51208. AUTOTRANSPORTER. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8GKS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTTPTFPTK TFKPTAMALA VATTLSACLG GGGGGTSAPD FNAGGTGIGS
60 70 80 90 100
NSRATTAKSA AVSYAGIKNE MCKDRSMLCA GRDDVAVTDR DAKINAPPPP
110 120 130 140 150
NLHTGDFPNP NDAYKNLINL KPAIEAGYTG RGVEVGIVDT GESVGSISFP
160 170 180 190 200
ELYGRKEHGY NENYKNYTAY MRKEAPEDGG GKDIEASFDD EAVIETEAKP
210 220 230 240 250
TDIRHVKEIG HIDLVSHIIG GRSVDGRPAG GIAPDATLHI MNTNDGTKNE
260 270 280 290 300
MMVAAIRNAW VKLGERGVRI VNNSFGTTSR AGTADLFQIA NSEEQYRQAL
310 320 330 340 350
LDYSGGDKTD EGIRLMQQSD YGNLSYHIRN KNMLFIFSTG NDAQAQPNTY
360 370 380 390 400
ALLPFYEKDA QKGIITVAGV DRSGEKFKRE MYGEPGTEPL EYGSNHCGIT
410 420 430 440 450
AMWCLSAPYE ASVRFTRTNP IQIAGTSFSA PIVTGTAALL LQKYPWMSND
460 470 480 490 500
NLRTTLLTTA QDIGAVGVDS KFGWGLLDAG KAMNGPASFP FGDFTADTKG
510 520 530 540 550
TSDIAYSFRN DISGTGGLIK KGGSQLQLHG NNTYTGKTII EGGSLVLYGN
560 570 580 590 600
NKSDMRVETK GALIYNGAAS GGSLNSDGIV YLADTDQSGA NETVHIKGSL
610 620 630 640 650
QLDGKGTLYT RLGKLLKVDG TAIIGGKLYM SARGKGAGYL NSTGRRVPFL
660 670 680 690 700
SAAKIGQDYS FFTNIETDGG LLASLDSVEK TAGSEGDTLS YYVRRGNAAR
710 720 730 740 750
TASAAAHSAP AGLKHAVEQG GSNLENLMVE LDASESSATP ETVETAAADR
760 770 780 790 800
TDMPGIRPYG ATFRAAAAVQ HANAADGVRI FNSLAATVYA DSTAAHADMQ
810 820 830 840 850
GRRLKAVSDG LDHNGTGLRV IAQTQQDGGT WEQGGVEGKM RGSTQTVGIA
860 870 880 890 900
AKTGENTTAA ATLGMGRSTW SENSANAKTD SISLFAGIRH DAGDIGYLKG
910 920 930 940 950
LFSYGRYKNS ISRSTGADEH AEGSVNGTLM QLGALGGVNV PFAATGDLTV
960 970 980 990 1000
EGGLRYDLLK QDAFAEKGSA LGWSGNSLTE GTLVGLAGLK LSQPLSDKAV
1010 1020 1030 1040 1050
LFATAGVERD LNGRDYTVTG GFTGATAATG KTGARNMPHT RLVAGLGADV
1060 1070 1080
EFGNGWNGLA RYSYAGSKQY GNHSGRVGVG YRF
Length:1,083
Mass (Da):113,640
Last modified:March 1, 2003 - v1
Checksum:iF34CE1D0EDB13C0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY150284 Genomic DNA. Translation: AAN71715.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY150284 Genomic DNA. Translation: AAN71715.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1UYNX-ray2.60X776-1083[»]
1UYOX-ray3.20X776-1083[»]
ProteinModelPortaliQ8GKS5.
SMRiQ8GKS5. Positions 785-1083.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi122586.NMB1969.

Protein family/group databases

MEROPSiS08.160.
TCDBi1.B.12.9.1. the autotransporter-1 (at-1) family.

Proteomic databases

PaxDbiQ8GKS5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4107ZYM. Bacteria.
COG1404. LUCA.

Miscellaneous databases

EvolutionaryTraceiQ8GKS5.

Family and domain databases

Gene3Di2.40.128.130. 1 hit.
3.40.50.200. 2 hits.
InterProiIPR005546. Autotransporte_beta.
IPR013425. Autotrns_rpt.
IPR000209. Peptidase_S8/S53_dom.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 4 hits.
PfamiPF03797. Autotransporter. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SMARTiSM00869. Autotransporter. 1 hit.
[Graphical view]
SUPFAMiSSF103515. SSF103515. 1 hit.
SSF52743. SSF52743. 3 hits.
TIGRFAMsiTIGR02601. autotrns_rpt. 1 hit.
PROSITEiPS51208. AUTOTRANSPORTER. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "In vivo expression of Neisseria meningitidis proteins homologous to the Haemophilus influenzae Hap and Hia autotransporters."
    van Ulsen P., van Alphen L., Hopman C.T., van der Ende A., Tommassen J.
    FEMS Immunol. Med. Microbiol. 32:53-64(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H44/76Imported.
  2. "A Neisserial autotransporter NalP modulating the processing of other autotransporters."
    van Ulsen P., van Alphen L., ten Hove J., Fransen F., van der Ley P., Tommassen J.
    Mol. Microbiol. 50:1017-1030(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H44/76Imported.
  3. "Structure of the translocator domain of a bacterial autotransporter."
    Oomen C.J., van Ulsen P., van Gelder P., Feijen M., Tommassen J., Gros P.
    EMBO J. 23:1257-1266(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 776-1083.

Entry informationi

Entry nameiQ8GKS5_NEIME
AccessioniPrimary (citable) accession number: Q8GKS5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 16, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.