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Q8GGH0

- Q8GGH0_9ENTR

UniProt

Q8GGH0 - Q8GGH0_9ENTR

Protein
Submitted name:

Regulatory protein

Gene

esp1396IC

Organism
Enterobacter sp. RFL1396
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei17 – 171Sulfate 1Imported
    Binding sitei24 – 241Sulfate 1; via amide nitrogenImported
    Binding sitei25 – 251Sulfate 3Imported
    Binding sitei35 – 351Sulfate 2Imported
    Binding sitei35 – 351Sulfate 4Imported
    Binding sitei39 – 391Sulfate 4Imported
    Binding sitei43 – 431Sulfate 4Imported
    Binding sitei63 – 631AcetateImported
    Binding sitei78 – 781Sulfate 5Imported

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro

    Protein family/group databases

    REBASEi17355. C.Esp1396I.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Regulatory proteinImported
    Gene namesi
    Name:esp1396ICImported
    Encoded oniPlasmid pEsp1396Imported
    OrganismiEnterobacter sp. RFL1396Imported
    Taxonomic identifieri211595 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacter

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3CLCX-ray2.80A/B/C/D1-79[»]
    3FYAX-ray3.00A/B1-79[»]
    3G5GX-ray2.80A/B/C/D/E/F/G/H/I/J/K/L/M/N1-79[»]
    3S8QX-ray2.10A/B1-79[»]
    3UFDX-ray2.80A/B/E/F1-79[»]
    4F8DX-ray1.50A/B1-79[»]
    4FBIX-ray1.50A/B/C/D1-79[»]
    4FN3X-ray1.79A/B1-79[»]
    4I6RX-ray1.38A/B1-79[»]
    4I6TX-ray2.00A/B1-79[»]
    4I6UX-ray1.97A/B/C/D/E/F1-79[»]
    4I8TX-ray3.00A/B1-79[»]
    4IA8X-ray1.85A/B1-79[»]
    4IVZX-ray3.10A/B/E/F1-79[»]
    4IWRX-ray2.40A/B/E/F1-79[»]
    ProteinModelPortaliQ8GGH0.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8GGH0.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 252Sulfate 2 bindingImported

    Family and domain databases

    Gene3Di1.10.260.40. 1 hit.
    InterProiIPR001387. Cro/C1-type_HTH.
    IPR010982. Lambda_DNA-bd_dom.
    [Graphical view]
    PfamiPF01381. HTH_3. 1 hit.
    [Graphical view]
    SMARTiSM00530. HTH_XRE. 1 hit.
    [Graphical view]
    SUPFAMiSSF47413. SSF47413. 1 hit.
    PROSITEiPS50943. HTH_CROC1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8GGH0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESFLLSKVS FVIKKIRLEK GMTQEDLAYK SNLDRTYISG IERNSRNLTI   50
    KSLELIMKGL EVSDVVFFEM LIKEILKHD 79
    Length:79
    Mass (Da):9,225
    Last modified:March 1, 2003 - v1
    Checksum:iB4DDF13A4F9E6998
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF527822 Genomic DNA. Translation: AAO16093.1.
    RefSeqiNP_862207.1. NC_004936.1.
    WP_011116951.1. NC_004936.1.

    Genome annotation databases

    GeneIDi1482839.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF527822 Genomic DNA. Translation: AAO16093.1 .
    RefSeqi NP_862207.1. NC_004936.1.
    WP_011116951.1. NC_004936.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3CLC X-ray 2.80 A/B/C/D 1-79 [» ]
    3FYA X-ray 3.00 A/B 1-79 [» ]
    3G5G X-ray 2.80 A/B/C/D/E/F/G/H/I/J/K/L/M/N 1-79 [» ]
    3S8Q X-ray 2.10 A/B 1-79 [» ]
    3UFD X-ray 2.80 A/B/E/F 1-79 [» ]
    4F8D X-ray 1.50 A/B 1-79 [» ]
    4FBI X-ray 1.50 A/B/C/D 1-79 [» ]
    4FN3 X-ray 1.79 A/B 1-79 [» ]
    4I6R X-ray 1.38 A/B 1-79 [» ]
    4I6T X-ray 2.00 A/B 1-79 [» ]
    4I6U X-ray 1.97 A/B/C/D/E/F 1-79 [» ]
    4I8T X-ray 3.00 A/B 1-79 [» ]
    4IA8 X-ray 1.85 A/B 1-79 [» ]
    4IVZ X-ray 3.10 A/B/E/F 1-79 [» ]
    4IWR X-ray 2.40 A/B/E/F 1-79 [» ]
    ProteinModelPortali Q8GGH0.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 17355. C.Esp1396I.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1482839.

    Miscellaneous databases

    EvolutionaryTracei Q8GGH0.

    Family and domain databases

    Gene3Di 1.10.260.40. 1 hit.
    InterProi IPR001387. Cro/C1-type_HTH.
    IPR010982. Lambda_DNA-bd_dom.
    [Graphical view ]
    Pfami PF01381. HTH_3. 1 hit.
    [Graphical view ]
    SMARTi SM00530. HTH_XRE. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47413. SSF47413. 1 hit.
    PROSITEi PS50943. HTH_CROC1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Esp1396I restriction-modification system: structural organization and mode of regulation."
      Cesnaviciene E., Mitkaite G., Stankevicius K., Janulaitis A., Lubys A.
      Nucleic Acids Res. 31:743-749(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: RFL1396Imported.
      Plasmid: pEsp1396
    2. "Structural analysis of the genetic switch that regulates the expression of restriction-modification genes."
      McGeehan J.E., Streeter S.D., Thresh S.J., Ball N., Ravelli R.B., Kneale G.G.
      Nucleic Acids Res. 36:4778-4787(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).
    3. "Structure of the restriction-modification controller protein C.Esp1396I."
      Ball N., Streeter S.D., Kneale G.G., McGeehan J.E.
      Acta Crystallogr. D 65:900-905(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).
    4. "Recognition of dual symmetry by the controller protein C.Esp1396I based on the structure of the transcriptional activation complex."
      McGeehan J.E., Ball N.J., Streeter S.D., Thresh S.J., Kneale G.G.
      Nucleic Acids Res. 40:4158-4167(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
    5. "The structural basis of differential DNA sequence recognition by restriction-modification controller proteins."
      Ball N.J., McGeehan J.E., Streeter S.D., Thresh S.J., Kneale G.G.
      Nucleic Acids Res. 40:10532-10542(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).
    6. "Structural analysis of DNA-protein complexes regulating the restriction-modification system Esp1396I."
      Martin R.N., McGeehan J.E., Ball N.J., Streeter S.D., Thresh S.J., Kneale G.G.
      Acta Crystallogr. F 69:962-966(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS).
    7. "Structural and mutagenic analysis of the RM controller protein C.Esp1396I."
      Martin R.N., McGeehan J.E., Kneale G.
      PLoS ONE 9:e98365-e98365(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.38 ANGSTROMS).

    Entry informationi

    Entry nameiQ8GGH0_9ENTR
    AccessioniPrimary (citable) accession number: Q8GGH0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, PlasmidImported

    External Data

    Dasty 3