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Q8GF87 (PGK_PHOLU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
OrganismPhotorhabdus luminescens (Xenorhabdus luminescens)
Taxonomic identifier29488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 387386Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145982

Regions

Nucleotide binding340 – 3434ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1131Substrate By similarity
Binding site1461Substrate By similarity
Binding site1971ATP By similarity
Binding site3141ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8GF87 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 5432B420A3F6C913

FASTA38741,455
        10         20         30         40         50         60 
MSVIKMTDLD LAGKRVLIRA DLNVPVKDGK VTSDARIRAS LPTIEAALKQ GAKVMITSHL 

        70         80         90        100        110        120 
GRPIEGEYNE EFSLKPVVDY LKEKLSSSVR LEKEYLEGVE VSEGELVVLE NVRFNKGEKK 

       130        140        150        160        170        180 
DDESLAKKYA SLCDIYVMDA FGTAHRAQAS THGVAKFAPV ACAGPLLFGE LEALGKALDN 

       190        200        210        220        230        240 
PARPMVAIVG GSKVSTKLTV LDTLSKIADQ LIVGGGIANT FVAAEGHNVG RSLYEDDLIP 

       250        260        270        280        290        300 
EAKKLLISCD IPVPTDVRVA TEFSETAEAT LKSSSDIKDD EQILDLGDES AQRLADILKN 

       310        320        330        340        350        360 
AKTILWNGPV GVFEFPNFRQ GTEIVARAIA DSDAFSIAGG GDTLAAIDLF GIADKISYIS 

       370        380 
TGGGAFLEFV EGKKLPAVVM LEERAKQ 

« Hide

References

[1]"Genomic islands in Photorhabdus."
Waterfield N.R., Daborn P.J., ffrench-Constant R.H.
Trends Microbiol. 10:541-545(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: W14.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF346500 Genomic DNA. Translation: AAO17214.1.

3D structure databases

ProteinModelPortalQ8GF87.
SMRQ8GF87. Positions 2-387.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ8GF87.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG0126.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_PHOLU
AccessionPrimary (citable) accession number: Q8GF87
Entry history
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 53 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways