Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Muconolactone Delta-isomerase

Gene

clcF

Organism
Rhodococcus opacus (Nocardia opaca)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

+-muconolactone = 5-oxo-4,5-dihydrofuran-2-acetate.UniRule annotation

Pathwayi: beta-ketoadipate pathway

This protein is involved in step 3 of the subpathway that synthesizes 5-oxo-4,5-dihydro-2-furylacetate from catechol.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. Muconolactone Delta-isomerase (clcF), Muconolactone Delta-isomerase (EP51_30995), Muconolactone Delta-isomerase (catC), Muconolactone Delta-isomerase (R1CP_29610)
This subpathway is part of the pathway beta-ketoadipate pathway, which is itself part of Aromatic compound metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-oxo-4,5-dihydro-2-furylacetate from catechol, the pathway beta-ketoadipate pathway and in Aromatic compound metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Aromatic hydrocarbons catabolismUniRule annotation

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14666.
UniPathwayiUPA00157; UER00260.

Names & Taxonomyi

Protein namesi
Recommended name:
Muconolactone Delta-isomeraseUniRule annotation (EC:5.3.3.4UniRule annotation)
Short name:
MIaseUniRule annotation
Gene namesi
Name:clcFImported
Encoded oniPlasmid p1CPImported
OrganismiRhodococcus opacus (Nocardia opaca)Imported
Taxonomic identifieri37919 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ZNJX-ray2.101/2/3/4/5/6/7/8/9/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/R/S/T/U/V1-94[»]
3ZNUX-ray1.65A/B/C/D/E/F/G/H/I/J1-94[»]
3ZO7X-ray2.22A/B/C/D/E/F/G/H/I/J1-94[»]
4FPIX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/R/S/T/U1-94[»]
ProteinModelPortaliQ8G9L0.
SMRiQ8G9L0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 89MIaseInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the muconolactone Delta-isomerase family.UniRule annotation

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR026029. MLI_dom.
IPR003464. Muconolactone_d_Isoase.
[Graphical view]
PfamiPF02426. MIase. 1 hit.
[Graphical view]
PIRSFiPIRSF001486. CatC. 1 hit.
ProDomiPD006619. Muconolactone_d_Isoase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54909. SSF54909. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8G9L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYLVRMTVN LPRNLDPREE ERLKASEKAR SRTLQEQGQW RYLWRTTGKY
60 70 80 90
GNISVFDVNS HDELHEILWS LPFFPYLTID VEPLSHHPAR VGKD
Length:94
Mass (Da):11,194
Last modified:March 1, 2003 - v1
Checksum:i610E6289A5EE9F5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ439407 Genomic DNA. Translation: CAD28145.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ439407 Genomic DNA. Translation: CAD28145.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ZNJX-ray2.101/2/3/4/5/6/7/8/9/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/R/S/T/U/V1-94[»]
3ZNUX-ray1.65A/B/C/D/E/F/G/H/I/J1-94[»]
3ZO7X-ray2.22A/B/C/D/E/F/G/H/I/J1-94[»]
4FPIX-ray2.20A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/R/S/T/U1-94[»]
ProteinModelPortaliQ8G9L0.
SMRiQ8G9L0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00157; UER00260.
BioCyciMetaCyc:MONOMER-14666.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR026029. MLI_dom.
IPR003464. Muconolactone_d_Isoase.
[Graphical view]
PfamiPF02426. MIase. 1 hit.
[Graphical view]
PIRSFiPIRSF001486. CatC. 1 hit.
ProDomiPD006619. Muconolactone_d_Isoase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54909. SSF54909. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8G9L0_RHOOP
AccessioniPrimary (citable) accession number: Q8G9L0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, PlasmidImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.