Q8G7Z8 (MURI_BIFLO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	BL0086

Organism

Bifidobacterium longum (strain NCC 2705)

Taxonomic identifier

206672 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	Glutamate racemase HAMAP MF_00258		PRO_0000095455

Sequences

	Sequence		Length	Mass (Da)
	Q8G7Z8 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 2670D9EAC8F3ECD6	FASTA	264	29,043
	10 20 30 40 50 60 MSSSAPIGVF DSGLGGISVA RQIAKDMPAE HVLYFGDSAN APYGIKTPEQ VRALSFDIVE 70 80 90 100 110 120 RFVRQGVKAV VIACNTATSA AVNDLREHYD IPIIGMEPAL KVACDRGDVP SDPHHIPQRV 130 140 150 160 170 180 IVAATPLTLR ERKFAKLMDR FDSNNTIFKE PCPDLVEIVE SGRLGDHDLV MRTLHGYFDQ 190 200 210 220 230 240 YDMEHIDSVV LGCTHFVFYR DYFRELLPER AAVIDGNEGT VRHLGVVLES LGKLAPEDAT 250 260 GGVELANSDP SERIAELSRK LLNV

References

[1]

"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract." Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F. Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed: 12381787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCC 2705.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014295 Genomic DNA. Translation: AAN23951.1.
RefSeq	NP_695315.1. NC_004307.2.
3D structure databases
ProteinModelPortal	Q8G7Z8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1022329.
GenomeReviews	Gene locus BL0086 in contig AE014295_GR.
KEGG	blo:BL0086.
PATRIC	21117213. VBIBifLon107831_0093.
Phylogenomic databases
HOGENOM	HBG645102.
OMA	ARTNAMI.
PhylomeDB	Q8G7Z8.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	BLON206672:BL0086-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BIFLO

Accession

Primary (citable) accession number: Q8G7Z8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 11, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program