Q8G7K5 (Q8G7K5_BIFLO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Beta-galactosidase PIRNR PIRNR001084
Short name=Beta-gal PIRNR PIRNR001084
EC=3.2.1.23 PIRNR PIRNR001084

Gene names

Name:	bgaB EMBL AAN24101.1
Ordered Locus Names:	BL0259

Organism

Bifidobacterium longum (strain NCC 2705)

Taxonomic identifier

206672 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	710 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. PIRNR PIRNR001084
Sequence similarities	Belongs to the glycosyl hydrolase 42 family. PIRNR PIRNR001084

Ontologies

Keywords
Molecular function	Glycosidase PIRNR PIRNR001084 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	beta-galactosidase complex Inferred from electronic annotation. Source: InterPro
Molecular function	beta-galactosidase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	161	1	Proton donor By similarity PIRSR PIRSR001084-1
	Active site	320	1	Nucleophile By similarity PIRSR PIRSR001084-1
	Binding site	122	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	160	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	328	1	Substrate By similarity PIRSR PIRSR001084-2

Sequences

	Sequence		Length	Mass (Da)
	Q8G7K5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 125246939CDBFF61	FASTA	710	79,004
	10 20 30 40 50 60 MTTHRAFRWP SLLTESGRGI AFGGDYNPDQ WPEETLDEDI RLMGEAGVNV VSLAIFSWDK 70 80 90 100 110 120 IEPVEGAFTF EWLDHVIDRL GRAGIAVDLA SATAAAPLWL YESHPEVLPV DRYGHTVNAG 130 140 150 160 170 180 SRQSWQPTSP VFKEYALRLC RRLAEHYKDN PYVTAWHMGN EYGWNNRYDY SDNALAAFRT 190 200 210 220 230 240 WCEAKYGTID ALNEAWGTAF WSQHVNSFDE VLLPRHMGGD AMVNPSQQLD YERFGNDMLL 250 260 270 280 290 300 DFYKAERDAI EQICPDKPFT TNFMVSTDQC VMNYAKWADE VDFVSNDHYF HEGESHLDEL 310 320 330 340 350 360 ACSDALMDSL ALGKPWYVME HSTSAVQWKP LNTRKRAGEL MRDSLAHVAM GADAICFFQW 370 380 390 400 410 420 RQSKSGAEAF HSAMLPHAGA DSKVFRGVCE LGKALKTLSD AGLQGTELER AGTAILFSAE 430 440 450 460 470 480 SEWATRSETL PSMKLNHWHD VRDWYRGFLD AGLRADVVPL AYDWTGYKTI VLPTVLSLSD 490 500 510 520 530 540 EDVLRIADFA KAGGTVIVGY AAGLIDEHFH IGLGGYPGAG NGLLRDMLGI RSEEFNILGE 550 560 570 580 590 600 EAEGEPSEIS LSNGLTTRLW QNDVTSVAAD TTVLASYAGE SAADWELERT PAITSRPYGN 610 620 630 640 650 660 GTAIYVGCDL NRHDIAQLLK ALGSRWQELS AQPTESGQTP TYPTTDPRIL HTIRRSADGS 670 680 690 700 710 TRFDFYLNRS NQPVAVNGIE GEPIIAYRCE ADTTGYTLNR NAILIAKASC

References

[1]

"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract." Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F. Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed: 12381787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCC 2705.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014295 Genomic DNA. Translation: AAN24101.1.
RefSeq	NP_695465.1. NC_004307.2.
3D structure databases
HSSP	HSSP built from PDB template 1KWG based on UniProtKB O69315.
ProteinModelPortal	Q8G7K5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1023317.
GenomeReviews	Gene locus BL0259 in contig AE014295_GR.
KEGG	blo:BL0259.
NMPDR	fig|206672.1.peg.234.
PATRIC	21119063. VBIBifLon107831_0994.
Phylogenomic databases
HOGENOM	HBG476453.
OMA	ESEWATR.
ProtClustDB	CLSK572549.
Family and domain databases
InterPro	IPR013739. Beta_galactosidase_C. IPR013738. Beta_galactosidase_Trimer. IPR003476. Glyco_hydro_42. IPR013529. Glyco_hydro_42_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K12308.
Pfam	PF02449. Glyco_hydro_42. 1 hit. PF08533. Glyco_hydro_42C. 1 hit. PF08532. Glyco_hydro_42M. 1 hit. [Graphical view]
PIRSF	PIRSF001084. B-galactosidase. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8G7K5_BIFLO

Accession

Primary (citable) accession number: Q8G7K5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)