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Q8G7I6

- G6PI_BIFLO

UniProt

Q8G7I6 - G6PI_BIFLO

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei374 – 3741Proton donorUniRule annotation
Active sitei405 – 4051UniRule annotation
Active sitei529 – 5291UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBLON206672:GI1E-955-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Synonyms:gpi
Ordered Locus Names:BL0279
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000000439: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 566566Glucose-6-phosphate isomerasePRO_0000180600Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi206672.BL0279.

Structurei

3D structure databases

ProteinModelPortaliQ8G7I6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiMIALTHY.
OrthoDBiEOG64R61J.
PhylomeDBiQ8G7I6.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G7I6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAINPPVDAT QTPEWAALQK HYDELQVEGV SLKKWFAEDA ERVEKLSFDA
60 70 80 90 100
GDLHFDLSKN LIKPETLQLF ANLAKAVKLD ERTKAMYTGV HINNTEDRAV
110 120 130 140 150
LHTALRRPVE DEGKYIVDGQ DTVKDVRETL DKIYAFADDV RSGKWTGVTG
160 170 180 190 200
RKIETVVNIG IGGSDLGPVM VYEALKPYAD AGISARYISN IDPNDLAEKT
210 220 230 240 250
KGLDPETTLF IIVSKTFTTL ETLTNAREAR TWLLEELTAN GAIAEGDEAQ
260 270 280 290 300
KAEAIKKHFV AVSTNLEKVE EFGIDPNNAF GFWNWVGGRY SVDSAVGTSL
310 320 330 340 350
AVVFGPARFE EFLHGFHEID EYFANTPFEK NVVVLLGMLN VWYRNFFKVA
360 370 380 390 400
SHAVLPYDQY LHRFPAYLQQ LTMESNGKSV RWDGTPVTSE TGEIFWGEPG
410 420 430 440 450
TNGQHAFYQL IHQGTQLIPA DFIAFVNTPN PTKDGDQDVH ELFLGNYFAQ
460 470 480 490 500
TKALAFGKTA DEVRAEGTPE EIVPARVFSG NRPTTSIFGV ALTPFALGEL
510 520 530 540 550
IALYEHITFV EGTVWGLDSY DQWGVELGKQ LAKQITPAIS QDDDALAAQD
560
ASTQSLIKFY RANREF
Length:566
Mass (Da):62,998
Last modified:March 1, 2003 - v1
Checksum:iA68089F8BAD007B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA. Translation: AAN24120.1.
RefSeqiNP_695484.1. NC_004307.2.

Genome annotation databases

EnsemblBacteriaiAAN24120; AAN24120; BL0279.
GeneIDi1022330.
KEGGiblo:BL0279.
PATRICi21119107. VBIBifLon107831_1016.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA. Translation: AAN24120.1 .
RefSeqi NP_695484.1. NC_004307.2.

3D structure databases

ProteinModelPortali Q8G7I6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 206672.BL0279.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN24120 ; AAN24120 ; BL0279 .
GeneIDi 1022330.
KEGGi blo:BL0279.
PATRICi 21119107. VBIBifLon107831_1016.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261371.
KOi K01810.
OMAi MIALTHY.
OrthoDBi EOG64R61J.
PhylomeDBi Q8G7I6.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci BLON206672:GI1E-955-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
    Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
    Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCC 2705.

Entry informationi

Entry nameiG6PI_BIFLO
AccessioniPrimary (citable) accession number: Q8G7I6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3