ID   NTPA_BIFLO              Reviewed;         252 AA.
AC   Q8G7I1;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   16-JUN-2009, entry version 33.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=BL0285;
OS   Bifidobacterium longum.
OC   Bacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=216816;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCC 2705;
RX   MEDLINE=22294977; PubMed=12381787; DOI=10.1073/pnas.212527599;
RA   Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B.,
RA   Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M.,
RA   Pridmore R.D., Arigoni F.;
RT   "The genome sequence of Bifidobacterium longum reflects its adaptation
RT   to the human gastrointestinal tract.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; AE014295; AAN24125.1; -; Genomic_DNA.
DR   RefSeq; NP_695489.1; -.
DR   HSSP; P52061; 1K7K.
DR   GeneID; 1022368; -.
DR   GenomeReviews; AE014295_GR; BL0285.
DR   KEGG; blo:BL0285; -.
DR   NMPDR; fig|206672.1.peg.258; -.
DR   HOGENOM; Q8G7I1; -.
DR   OMA; Q8G7I1; NACLKAS.
DR   BioCyc; BLON206672:BL0285-MON; -.
DR   BRENDA; 3.6.1.15; 39917.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p-like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    252       Nucleoside-triphosphatase.
FT                                /FTId=PRO_0000178134.
SQ   SEQUENCE   252 AA;  26418 MW;  9ADE11FC052CF3F0 CRC64;
     MQIVVATHNE GKLVEIRRIL EEDLGADAEN IELVSAGSLH LPDPVETGVT FQENALLKAR
     AVAIRTGLPA VADDSGLIVD VMGNAPGILS ARWAGAHGHD KANNALLLAQ IEDIPDDKRT
     ARFRCAAALV VPDTETGADV TGGVAADGIT VHTTAADGSP APVHARYAIK SETVELGDMP
     GRIIREARGV HGFGYDPLFV PDDQPAGRVS TEPDHEGEPL TSAEMTPAEK NAISHRGKAL
     KALVPAIEAL LH
//