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Q8G6P9

- PKNB_BIFLO

UniProt

Q8G6P9 - PKNB_BIFLO

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Protein

Probable serine/threonine-protein kinase PknB

Gene

pknB

Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431ATPPROSITE-ProRule annotation
Active sitei146 – 1461Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 289ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLON206672:GI1E-1262-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase PknB (EC:2.7.11.1)
Gene namesi
Name:pknB
Ordered Locus Names:BL0589
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000000439: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 690690Probable serine/threonine-protein kinase PknBPRO_0000171185Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi206672.BL0589.

Structurei

3D structure databases

ProteinModelPortaliQ8G6P9.
SMRiQ8G6P9. Positions 6-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 285272Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini399 – 46769PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini468 – 53669PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini540 – 60162PASTA 3PROSITE-ProRule annotationAdd
BLAST
Domaini602 – 66665PASTA 4PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi667 – 68923Gly-richAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 4 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiMSKNPAN.
OrthoDBiEOG6B35XT.
PhylomeDBiQ8G6P9.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G6P9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTSMPTALA GGRYQLGQLI GRGGMAEVHV ALDTRLGRTV AVKIMRADLA
60 70 80 90 100
NDDIFLARFR REAHAVAQMN NPNIVNIYDS GEELVSSESG DAERLPYIVM
110 120 130 140 150
EYVKGQTLRD IIKVNGALSQ RDCEQVMLGV LNALDYSHRM GIIHRDIKPG
160 170 180 190 200
NIMISEQGVV KVMDFGIARA LDDSAATMTQ SQGVVGTAQY LSPEQARGET
210 220 230 240 250
VDMRSDLYSA GCVLYEMLTG RPPFTGDSAV AIAYQHVSEV ATPPSAAVPG
260 270 280 290 300
LPKMWDSICA KAMAKDRQNR YATASEFKTD ILTYMNGGVP VAAAFNPLTD
310 320 330 340 350
LSNMKARKEA ERDLPTTPVE PHQQPTQAFN PVTGQFEQIP PANGANAAAL
360 370 380 390 400
QSRAQQRAAA AKAKKRKKII IGSVIAAIVA VLVIVGIVFA MNGSGNKSSE
410 420 430 440 450
DTVTIPEVCN ASTSKDNIKL KLEASGLKMT EKQDTDSTEP EGTCTKMSPD
460 470 480 490 500
AGSKVAKGSA VKVWFSAGPQ STQVPDVKER SQEEARSILE SAGFKVNAAV
510 520 530 540 550
KTEDSADIAK DMVTKTDPAA GQSVPKGTTI TIYVSSGMTT VPSNLVGQSK
560 570 580 590 600
DSVLQQYEGK FSFTVEQESS DTVEAGLITR VSPDSGSSIA QGGFITIWVS
610 620 630 640 650
TGKEKVAVPN ITAGTDYVTA ELMLKAVGLK AQANGPTGST AVVVSINPGA
660 670 680 690
GSQVDAGSTV TITTKAGSTG GGTGTGDGGN GTGNGGGTGE
Length:690
Mass (Da):72,244
Last modified:March 1, 2003 - v1
Checksum:i6A419EA8CED5D92D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA. Translation: AAN24413.1.
RefSeqiNP_695777.1. NC_004307.2.

Genome annotation databases

EnsemblBacteriaiAAN24413; AAN24413; BL0589.
GeneIDi1022968.
KEGGiblo:BL0589.
PATRICi21119765. VBIBifLon107831_1329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA. Translation: AAN24413.1 .
RefSeqi NP_695777.1. NC_004307.2.

3D structure databases

ProteinModelPortali Q8G6P9.
SMRi Q8G6P9. Positions 6-290.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 206672.BL0589.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN24413 ; AAN24413 ; BL0589 .
GeneIDi 1022968.
KEGGi blo:BL0589.
PATRICi 21119765. VBIBifLon107831_1329.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi MSKNPAN.
OrthoDBi EOG6B35XT.
PhylomeDBi Q8G6P9.

Enzyme and pathway databases

BioCyci BLON206672:GI1E-1262-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 4 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
    Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
    Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCC 2705.

Entry informationi

Entry nameiPKNB_BIFLO
AccessioniPrimary (citable) accession number: Q8G6P9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3