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Q8G6P9 (PKNB_BIFLO) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase PknB

EC=2.7.11.1
Gene names
Name:pknB
Ordered Locus Names:BL0589
OrganismBifidobacterium longum (strain NCC 2705) [Reference proteome] [HAMAP]
Taxonomic identifier206672 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium

Protein attributes

Sequence length690 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 4 PASTA domains.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 690690Probable serine/threonine-protein kinase PknB
PRO_0000171185

Regions

Domain14 – 285272Protein kinase
Domain399 – 46769PASTA 1
Domain468 – 53669PASTA 2
Domain540 – 60162PASTA 3
Domain602 – 66665PASTA 4
Nucleotide binding20 – 289ATP By similarity
Compositional bias667 – 68923Gly-rich

Sites

Active site1461Proton acceptor By similarity
Binding site431ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8G6P9 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 6A419EA8CED5D92D

FASTA69072,244
        10         20         30         40         50         60 
MSTSMPTALA GGRYQLGQLI GRGGMAEVHV ALDTRLGRTV AVKIMRADLA NDDIFLARFR 

        70         80         90        100        110        120 
REAHAVAQMN NPNIVNIYDS GEELVSSESG DAERLPYIVM EYVKGQTLRD IIKVNGALSQ 

       130        140        150        160        170        180 
RDCEQVMLGV LNALDYSHRM GIIHRDIKPG NIMISEQGVV KVMDFGIARA LDDSAATMTQ 

       190        200        210        220        230        240 
SQGVVGTAQY LSPEQARGET VDMRSDLYSA GCVLYEMLTG RPPFTGDSAV AIAYQHVSEV 

       250        260        270        280        290        300 
ATPPSAAVPG LPKMWDSICA KAMAKDRQNR YATASEFKTD ILTYMNGGVP VAAAFNPLTD 

       310        320        330        340        350        360 
LSNMKARKEA ERDLPTTPVE PHQQPTQAFN PVTGQFEQIP PANGANAAAL QSRAQQRAAA 

       370        380        390        400        410        420 
AKAKKRKKII IGSVIAAIVA VLVIVGIVFA MNGSGNKSSE DTVTIPEVCN ASTSKDNIKL 

       430        440        450        460        470        480 
KLEASGLKMT EKQDTDSTEP EGTCTKMSPD AGSKVAKGSA VKVWFSAGPQ STQVPDVKER 

       490        500        510        520        530        540 
SQEEARSILE SAGFKVNAAV KTEDSADIAK DMVTKTDPAA GQSVPKGTTI TIYVSSGMTT 

       550        560        570        580        590        600 
VPSNLVGQSK DSVLQQYEGK FSFTVEQESS DTVEAGLITR VSPDSGSSIA QGGFITIWVS 

       610        620        630        640        650        660 
TGKEKVAVPN ITAGTDYVTA ELMLKAVGLK AQANGPTGST AVVVSINPGA GSQVDAGSTV 

       670        680        690 
TITTKAGSTG GGTGTGDGGN GTGNGGGTGE 

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References

[1]"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCC 2705.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014295 Genomic DNA. Translation: AAN24413.1.
RefSeqNP_695777.1. NC_004307.2.

3D structure databases

ProteinModelPortalQ8G6P9.
SMRQ8G6P9. Positions 6-290.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING206672.BL0589.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN24413; AAN24413; BL0589.
GeneID1022968.
KEGGblo:BL0589.
PATRIC21119765. VBIBifLon107831_1329.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037185.
KOK08884.
OMATGKDPGT.
OrthoDBEOG6B35XT.
ProtClustDBCLSK572700.

Enzyme and pathway databases

BioCycBLON206672:GI1E-1262-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNB_BIFLO
AccessionPrimary (citable) accession number: Q8G6P9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: November 13, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families