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Q8G6P9

- PKNB_BIFLO

UniProt

Q8G6P9 - PKNB_BIFLO

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Protein

Probable serine/threonine-protein kinase PknB

Gene
pknB, BL0589
Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431ATP By similarity
Active sitei146 – 1461Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 289ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLON206672:GI1E-1262-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase PknB (EC:2.7.11.1)
Gene namesi
Name:pknB
Ordered Locus Names:BL0589
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000000439: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 690690Probable serine/threonine-protein kinase PknBPRO_0000171185Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi206672.BL0589.

Structurei

3D structure databases

ProteinModelPortaliQ8G6P9.
SMRiQ8G6P9. Positions 6-290.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 285272Protein kinaseAdd
BLAST
Domaini399 – 46769PASTA 1Add
BLAST
Domaini468 – 53669PASTA 2Add
BLAST
Domaini540 – 60162PASTA 3Add
BLAST
Domaini602 – 66665PASTA 4Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi667 – 68923Gly-richAdd
BLAST

Sequence similaritiesi

Contains 4 PASTA domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiMSKNPAN.
OrthoDBiEOG6B35XT.
PhylomeDBiQ8G6P9.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G6P9-1 [UniParc]FASTAAdd to Basket

« Hide

MSTSMPTALA GGRYQLGQLI GRGGMAEVHV ALDTRLGRTV AVKIMRADLA    50
NDDIFLARFR REAHAVAQMN NPNIVNIYDS GEELVSSESG DAERLPYIVM 100
EYVKGQTLRD IIKVNGALSQ RDCEQVMLGV LNALDYSHRM GIIHRDIKPG 150
NIMISEQGVV KVMDFGIARA LDDSAATMTQ SQGVVGTAQY LSPEQARGET 200
VDMRSDLYSA GCVLYEMLTG RPPFTGDSAV AIAYQHVSEV ATPPSAAVPG 250
LPKMWDSICA KAMAKDRQNR YATASEFKTD ILTYMNGGVP VAAAFNPLTD 300
LSNMKARKEA ERDLPTTPVE PHQQPTQAFN PVTGQFEQIP PANGANAAAL 350
QSRAQQRAAA AKAKKRKKII IGSVIAAIVA VLVIVGIVFA MNGSGNKSSE 400
DTVTIPEVCN ASTSKDNIKL KLEASGLKMT EKQDTDSTEP EGTCTKMSPD 450
AGSKVAKGSA VKVWFSAGPQ STQVPDVKER SQEEARSILE SAGFKVNAAV 500
KTEDSADIAK DMVTKTDPAA GQSVPKGTTI TIYVSSGMTT VPSNLVGQSK 550
DSVLQQYEGK FSFTVEQESS DTVEAGLITR VSPDSGSSIA QGGFITIWVS 600
TGKEKVAVPN ITAGTDYVTA ELMLKAVGLK AQANGPTGST AVVVSINPGA 650
GSQVDAGSTV TITTKAGSTG GGTGTGDGGN GTGNGGGTGE 690
Length:690
Mass (Da):72,244
Last modified:March 1, 2003 - v1
Checksum:i6A419EA8CED5D92D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014295 Genomic DNA. Translation: AAN24413.1.
RefSeqiNP_695777.1. NC_004307.2.

Genome annotation databases

EnsemblBacteriaiAAN24413; AAN24413; BL0589.
GeneIDi1022968.
KEGGiblo:BL0589.
PATRICi21119765. VBIBifLon107831_1329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014295 Genomic DNA. Translation: AAN24413.1 .
RefSeqi NP_695777.1. NC_004307.2.

3D structure databases

ProteinModelPortali Q8G6P9.
SMRi Q8G6P9. Positions 6-290.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 206672.BL0589.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN24413 ; AAN24413 ; BL0589 .
GeneIDi 1022968.
KEGGi blo:BL0589.
PATRICi 21119765. VBIBifLon107831_1329.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi MSKNPAN.
OrthoDBi EOG6B35XT.
PhylomeDBi Q8G6P9.

Enzyme and pathway databases

BioCyci BLON206672:GI1E-1262-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 4 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
    Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
    Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCC 2705.

Entry informationi

Entry nameiPKNB_BIFLO
AccessioniPrimary (citable) accession number: Q8G6P9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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