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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei418NucleophileUniRule annotation1
Active sitei471Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciBLON206672:G1FZZ-674-MONOMER
UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:BL0999
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000000439 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001886841 – 7371,4-alpha-glucan branching enzyme GlgBAdd BLAST737

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi206672.BL0999

Structurei

3D structure databases

ProteinModelPortaliQ8G5L0
SMRiQ8G5L0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9C Bacteria
COG0296 LUCA
HOGENOMiHOG000283037
KOiK00700
OMAiEVVHGKS
PhylomeDBiQ8G5L0

Family and domain databases

Gene3Di2.60.40.101 hit
2.60.40.11801 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 2 hits
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 2 hits
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q8G5L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVAQGDLDA TSNAEFYNPH GVLGGHLGIG KHADTATIRV LRPLAKSVTI
60 70 80 90 100
LTQDGEYPMT HEYNGVFVVT VPASGTKKQP TIPDYRVRTE WESGAVLIED
110 120 130 140 150
DPYRYMPTVG DMDTYLFGEG RHEKLWETLG AHVLRYDDPM GGADGTPGEQ
160 170 180 190 200
VVGTAFSVWA PNAHAVRVVG NFNAWDGRRH AMRELGSSGV WEIFIPGIGA
210 220 230 240 250
GETYKFQILN ANYTWEMKAD PMERQHEVPP STASIVTEST YKWNDDAWMQ
260 270 280 290 300
HRRTTNPHDG PVSIYEVHAG SWKQGLTYRD LAKQLVDYVK QEGFTHVEFM
310 320 330 340 350
PLAQHPFSGS WGYQVTGYYA VDSRLGSPDD FRYLVDQFHQ AGIGVIMDWV
360 370 380 390 400
PAHFPKDAFA LGRFDGTPLY EDPDPLRGEH PEWGTYVFNF GRREVRNFLV
410 420 430 440 450
ANALFWLEDL HVDALRVDAV SSMLYLDYSR EPGHWRPNIY GGRENLEAID
460 470 480 490 500
FLKEATATAY KNNPGVMVIA EESTAWPGIT APTSAGGIGF GMKWNMGWMH
510 520 530 540 550
DTLEYLHEEP INRKWHHNEI TFSMVYAYSE HYVLPISHDE VVYGKGSLYG
560 570 580 590 600
KMPGDDWQKL AGVRSMFAYQ WAHPGKKLSF MGNELAQWGE WDHDASIDWD
610 620 630 640 650
CLNWQEHRQV QTMVADLNAF YKAHPALWSQ DFDPAGFQWL TSDDADHNTL
660 670 680 690 700
SFLRIGTKGE TLAVVVNFSG EAWSDYQVAL PTGGKWTEVF TTDDAKYGGS
710 720 730
DIHNGTFEAV EGEYHSRPFS AKITVPALGV VFLKPED
Length:737
Mass (Da):83,051
Last modified:March 1, 2003 - v1
Checksum:i035A1580871A21F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA Translation: AAN24807.1
RefSeqiNP_696171.1, NC_004307.2
WP_011068245.1, NC_004307.2

Genome annotation databases

EnsemblBacteriaiAAN24807; AAN24807; BL0999
GeneIDi1022518
KEGGiblo:BL0999
PATRICifig|206672.9.peg.702

Similar proteinsi

Entry informationi

Entry nameiGLGB_BIFLO
AccessioniPrimary (citable) accession number: Q8G5L0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2003
Last modified: February 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome