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Reviewed, UniProtKB/Swiss-Prot Q8G5G8 (PPNK_BIFLO)

Last modified June 16, 2009. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23
Gene names
Name: ppnK
Ordered Locus Names: BL1044
OrganismBifidobacterium longum [Complete proteome] [HAMAP]
Taxonomic identifier216816 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmetabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 342342Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
PRO_0000120601

Sequences

Sequence LengthMass (Da)Tools
Q8G5G8-1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 3C215EC0045DB211

FASTA34236,613
        10         20         30         40         50         60 
MAKRNAVVVT HTRLRQTGTV VAEAVSQLRV AGFEVAIIDN TEAPDFGVQP PCVSDDTEIV 

        70         80         90        100        110        120 
VVLGGDGTIL RAAELVHCTQ VPILGVNMGH VGFLAEFESF QIDEAIRRVS THDYSIDERM 

       130        140        150        160        170        180 
IAHVDVWLPG ATKPIEDWAL NDITLERADR GKMVELSIRV DDVEMNSFGA DGVIVSTPTG 

       190        200        210        220        230        240 
STAYAFSAGG PVMWPNVKAL QLIPLAAHAL FARPLIIGSG STFTIDILDD SMSEGWICCD 

       250        260        270        280        290        300 
GRRQRALPQG TRVMVRESRD TLRLARLSGV PFTNRLVSKF DLPVVGWREH ARNEASSQSL 

       310        320        330        340 
HHGHTFPAAA YAAGVAVAVA GDAGVAGTDP DKPGERDGKA GA 

« Hide

References

[1]"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed: 12381787] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCC 2705.

Cross-references

Sequence databases

AE014295 Genomic DNA. Translation: AAN24850.1.
RefSeqNP_696214.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1022572.
GenomeReviewsGene locus BL1044 in contig AE014295_GR.
KEGGblo:BL1044.
NMPDRfig|206672.1.peg.981.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ8G5G8.
OMAQ8G5G8. NDGKELA.

Enzyme and pathway databases

BioCycBLON206672:BL1044-MON.
BRENDA2.7.1.23. 39917.

Family and domain databases

HAMAPMF_00361.
[Tree]
InterProIPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. ATP_NADK.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePPNK_BIFLO
AccessionPrimary (citable) accession number: Q8G5G8
Entry history
Integrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: March 1, 2003
Last modified: June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents