Q8G552 (Q8G552_BIFLO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Beta-galactosidase PIRNR PIRNR001084
Short name=Beta-gal PIRNR PIRNR001084
EC=3.2.1.23 PIRNR PIRNR001084

Gene names

Name:	bga EMBL AAN24973.1
Ordered Locus Names:	BL1168

Organism

Bifidobacterium longum (strain NCC 2705)

Taxonomic identifier

206672 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	691 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. PIRNR PIRNR001084
Sequence similarities	Belongs to the glycosyl hydrolase 42 family. PIRNR PIRNR001084

Ontologies

Keywords
Molecular function	Glycosidase PIRNR PIRNR001084 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	beta-galactosidase complex Inferred from electronic annotation. Source: InterPro
Molecular function	beta-galactosidase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	160	1	Proton donor By similarity PIRSR PIRSR001084-1
	Active site	318	1	Nucleophile By similarity PIRSR PIRSR001084-1
	Binding site	121	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	159	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	326	1	Substrate By similarity PIRSR PIRSR001084-2

Sequences

	Sequence		Length	Mass (Da)
	Q8G552 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 095F4F91AB684D69	FASTA	691	77,415
	10 20 30 40 50 60 MERKEFKWPQ PLAGNKPRIW YGGDYNPDQW PEEVWDEDVA LMQQAGVNLV SVAIFSWAKL 70 80 90 100 110 120 EPEEGVYDFD WLDRVIDKLG KAGIAVDLAS GTASPPMWMT QAHPEILWVD YRGDVCQPGA 130 140 150 160 170 180 RQHWRATSPV FLDYALSLCR KMAEHYKDNP YVVSWHVSNE YGCHNRFDYS EDAERAFQKW 190 200 210 220 230 240 CEKKYGTIDA VNDAWGTAFW AQRMNNFSEI IPPRFIGDGN FMNPGKLLDW KRFSSDALLD 250 260 270 280 290 300 FYKAERDALL EIAPKPQTTN FMVSAGGAGI DYDKWGYDVD FVSNDHYFTP GEAHFDELAY 310 320 330 340 350 360 SASLCDGIAR KNPWFLMEHS SSAVNWRPIN YRVEPGELVR DSLAHLAMGS DAICYFQWRQ 370 380 390 400 410 420 SKAGAEKWHS SMVPHAGPDS QIFRDVCELG ADLNKLADEG LLSTKLVKSK VAVVFDYESQ 430 440 450 460 470 480 WATEHTATPT QEVRHWTEPL AWFRALADNG LTADVVPVRG PWDEYEAVVL PSLTILSEET 490 500 510 520 530 540 TRRVREYVAN GGKLFVTYYT GLVDDKDHVW LGGYPGSIRD VVGVRVEEFA PMGNDFPGAM 550 560 570 580 590 600 DHLDLDNGTV AHDFADVITS VADTAHVVAS FKADKWTGFD GAPAITVNDF GDGKAAYVGA 610 620 630 640 650 660 RLGREGLAKS LPVLLEELGI ETSAEDDRGE VLRVERADET GENHFVFLFN RTHDVAVVDV 670 680 690 EGEPLVASLA QVNESEHTAA IQPNGVLVVK L

References

[1]

"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract." Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F. Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed: 12381787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCC 2705.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014295 Genomic DNA. Translation: AAN24973.1.
RefSeq	NP_696337.1. NC_004307.2.
3D structure databases
HSSP	HSSP built from PDB template 1KWG based on UniProtKB O69315.
ProteinModelPortal	Q8G552.
ModBase	Search...
Protein family/group databases
CAZy	GH42. Glycoside Hydrolase Family 42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1022705.
GenomeReviews	Gene locus BL1168 in contig AE014295_GR.
KEGG	blo:BL1168.
NMPDR	fig|206672.1.peg.1104.
PATRIC	21118831. VBIBifLon107831_0878.
Phylogenomic databases
HOGENOM	HBG476453.
OMA	PLAWFRA.
ProtClustDB	CLSK2462116.
Family and domain databases
InterPro	IPR013739. Beta_galactosidase_C. IPR013738. Beta_galactosidase_Trimer. IPR003476. Glyco_hydro_42. IPR013529. Glyco_hydro_42_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K12308.
Pfam	PF02449. Glyco_hydro_42. 1 hit. PF08533. Glyco_hydro_42C. 1 hit. PF08532. Glyco_hydro_42M. 1 hit. [Graphical view]
PIRSF	PIRSF001084. B-galactosidase. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8G552_BIFLO

Accession

Primary (citable) accession number: Q8G552

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)