Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8G4G1

- PKNA2_BIFLO

UniProt

Q8G4G1 - PKNA2_BIFLO

Protein

Probable serine/threonine-protein kinase pknA2

Gene

pknA2

Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei43 – 431ATPPROSITE-ProRule annotation
    Active sitei140 – 1401Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi20 – 289ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. penicillin binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBLON206672:GI1E-264-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase pknA2 (EC:2.7.11.1)
    Gene namesi
    Name:pknA2
    Ordered Locus Names:BL1425
    OrganismiBifidobacterium longum (strain NCC 2705)
    Taxonomic identifieri206672 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
    ProteomesiUP000000439: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 757757Probable serine/threonine-protein kinase pknA2PRO_0000171184Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi206672.BL1425.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8G4G1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini14 – 274261Protein kinasePROSITE-ProRule annotationAdd
    BLAST
    Domaini466 – 53974PASTA 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini545 – 61470PASTA 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini615 – 68167PASTA 3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 3 PASTA domains.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000037187.
    KOiK00870.
    OMAiRISKRAN.
    OrthoDBiEOG6B35XT.
    PhylomeDBiQ8G4G1.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 3 hits.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 3 hits.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8G4G1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSENEPAQMI EGRYRIVRNI AEGGMATVYE AIDERLGRTV AIKVMHTQLA    50
    KGPHREQFVE RFRREANSAA SIANPHIVQV YDTGEFNGLD FLVMEYVHGV 100
    NLRHEMNAQG TFSVRETLRV VAETLDGLAS AHRAGVVHRD IKPENILIND 150
    RGHVQITDFG LAKAASQATL SSTGMLLGTA AYLAPEMIEN NQATAQGDLY 200
    SVGIMAWEML TGKVPFDSDN PVTLVFKHVH EDVPSVATVC QGIDPSVAAF 250
    IAHLTARQVD ARPTDGAAAA EELSQLAAKL PLEAWQYRLH AEPIGGDHTD 300
    ATAAALVGNI AEQAPLTGVP AGAATFKPSV PAFLADDVAS NTVDTGGAAD 350
    VNPPAPPVAP TTALDSSTPA DASAPHKTQI MAQSGSETQV LPQAGDAFTR 400
    ALAFSDEPDV ASNGTGPKKQ RSKKPLIIVL VIVLVLAAIG GTAGWWWFAG 450
    PGSYWSVPKP DDVTCDANAS TECSLAGADW ATYESTLKAL GIPYKTHKEY 500
    SDDVAEGKII SSSVNKTKAV VNSRISKRAN QELTVVVSKG VRMTTIPKDI 550
    LDANSANGKD PLNALKKAGF DNVKHDESKD EYSMDTPQGV ALTISPDPGT 600
    TAKHNDEVTV TLSKGPMPVT MPNIVGKTQD EMQAALGELK LTANVTEQYD 650
    DKVEAGQVIS ASQEAGAQLK WGDSVDVVIS KGPEMATIPS GLVGKQESAV 700
    TKTLEGLGFE VKTDKVLGGL FGTVRTVKSG DTDLSNGGKI RLRDANGNPT 750
    VITLTIV 757
    Length:757
    Mass (Da):80,088
    Last modified:March 1, 2003 - v1
    Checksum:iD7916F1B880268D1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014295 Genomic DNA. Translation: AAN25222.1.
    RefSeqiNP_696586.1. NC_004307.2.

    Genome annotation databases

    EnsemblBacteriaiAAN25222; AAN25222; BL1425.
    GeneIDi1021578.
    KEGGiblo:BL1425.
    PATRICi21117603. VBIBifLon107831_0283.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014295 Genomic DNA. Translation: AAN25222.1 .
    RefSeqi NP_696586.1. NC_004307.2.

    3D structure databases

    ProteinModelPortali Q8G4G1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 206672.BL1425.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN25222 ; AAN25222 ; BL1425 .
    GeneIDi 1021578.
    KEGGi blo:BL1425.
    PATRICi 21117603. VBIBifLon107831_0283.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000037187.
    KOi K00870.
    OMAi RISKRAN.
    OrthoDBi EOG6B35XT.
    PhylomeDBi Q8G4G1.

    Enzyme and pathway databases

    BioCyci BLON206672:GI1E-264-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 3 hits.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 3 hits.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
      Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
      Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCC 2705.

    Entry informationi

    Entry nameiPKNA2_BIFLO
    AccessioniPrimary (citable) accession number: Q8G4G1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3