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Q8G4G1

- PKNA2_BIFLO

UniProt

Q8G4G1 - PKNA2_BIFLO

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Protein
Probable serine/threonine-protein kinase pknA2
Gene
pknA2, BL1425
Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431ATP By similarity
Active sitei140 – 1401Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 289ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLON206672:GI1E-264-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase pknA2 (EC:2.7.11.1)
Gene namesi
Name:pknA2
Ordered Locus Names:BL1425
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000000439: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 757757Probable serine/threonine-protein kinase pknA2
PRO_0000171184Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi206672.BL1425.

Structurei

3D structure databases

ProteinModelPortaliQ8G4G1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 274261Protein kinase
Add
BLAST
Domaini466 – 53974PASTA 1
Add
BLAST
Domaini545 – 61470PASTA 2
Add
BLAST
Domaini615 – 68167PASTA 3
Add
BLAST

Sequence similaritiesi

Contains 3 PASTA domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037187.
KOiK00870.
OMAiRISKRAN.
OrthoDBiEOG6B35XT.
PhylomeDBiQ8G4G1.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G4G1-1 [UniParc]FASTAAdd to Basket

« Hide

MSENEPAQMI EGRYRIVRNI AEGGMATVYE AIDERLGRTV AIKVMHTQLA    50
KGPHREQFVE RFRREANSAA SIANPHIVQV YDTGEFNGLD FLVMEYVHGV 100
NLRHEMNAQG TFSVRETLRV VAETLDGLAS AHRAGVVHRD IKPENILIND 150
RGHVQITDFG LAKAASQATL SSTGMLLGTA AYLAPEMIEN NQATAQGDLY 200
SVGIMAWEML TGKVPFDSDN PVTLVFKHVH EDVPSVATVC QGIDPSVAAF 250
IAHLTARQVD ARPTDGAAAA EELSQLAAKL PLEAWQYRLH AEPIGGDHTD 300
ATAAALVGNI AEQAPLTGVP AGAATFKPSV PAFLADDVAS NTVDTGGAAD 350
VNPPAPPVAP TTALDSSTPA DASAPHKTQI MAQSGSETQV LPQAGDAFTR 400
ALAFSDEPDV ASNGTGPKKQ RSKKPLIIVL VIVLVLAAIG GTAGWWWFAG 450
PGSYWSVPKP DDVTCDANAS TECSLAGADW ATYESTLKAL GIPYKTHKEY 500
SDDVAEGKII SSSVNKTKAV VNSRISKRAN QELTVVVSKG VRMTTIPKDI 550
LDANSANGKD PLNALKKAGF DNVKHDESKD EYSMDTPQGV ALTISPDPGT 600
TAKHNDEVTV TLSKGPMPVT MPNIVGKTQD EMQAALGELK LTANVTEQYD 650
DKVEAGQVIS ASQEAGAQLK WGDSVDVVIS KGPEMATIPS GLVGKQESAV 700
TKTLEGLGFE VKTDKVLGGL FGTVRTVKSG DTDLSNGGKI RLRDANGNPT 750
VITLTIV 757
Length:757
Mass (Da):80,088
Last modified:March 1, 2003 - v1
Checksum:iD7916F1B880268D1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014295 Genomic DNA. Translation: AAN25222.1.
RefSeqiNP_696586.1. NC_004307.2.

Genome annotation databases

EnsemblBacteriaiAAN25222; AAN25222; BL1425.
GeneIDi1021578.
KEGGiblo:BL1425.
PATRICi21117603. VBIBifLon107831_0283.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014295 Genomic DNA. Translation: AAN25222.1 .
RefSeqi NP_696586.1. NC_004307.2.

3D structure databases

ProteinModelPortali Q8G4G1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 206672.BL1425.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN25222 ; AAN25222 ; BL1425 .
GeneIDi 1021578.
KEGGi blo:BL1425.
PATRICi 21117603. VBIBifLon107831_0283.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037187.
KOi K00870.
OMAi RISKRAN.
OrthoDBi EOG6B35XT.
PhylomeDBi Q8G4G1.

Enzyme and pathway databases

BioCyci BLON206672:GI1E-264-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
    Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
    Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCC 2705.

Entry informationi

Entry nameiPKNA2_BIFLO
AccessioniPrimary (citable) accession number: Q8G4G1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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