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Q8G4G1 (PKNA2_BIFLO) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase pknA2

EC=2.7.11.1
Gene names
Name:pknA2
Ordered Locus Names:BL1425
OrganismBifidobacterium longum (strain NCC 2705) [Reference proteome] [HAMAP]
Taxonomic identifier206672 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium

Protein attributes

Sequence length757 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 3 PASTA domains.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 757757Probable serine/threonine-protein kinase pknA2
PRO_0000171184

Regions

Domain14 – 274261Protein kinase
Domain466 – 53974PASTA 1
Domain545 – 61470PASTA 2
Domain615 – 68167PASTA 3
Nucleotide binding20 – 289ATP By similarity

Sites

Active site1401Proton acceptor By similarity
Binding site431ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8G4G1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: D7916F1B880268D1

FASTA75780,088
        10         20         30         40         50         60 
MSENEPAQMI EGRYRIVRNI AEGGMATVYE AIDERLGRTV AIKVMHTQLA KGPHREQFVE 

        70         80         90        100        110        120 
RFRREANSAA SIANPHIVQV YDTGEFNGLD FLVMEYVHGV NLRHEMNAQG TFSVRETLRV 

       130        140        150        160        170        180 
VAETLDGLAS AHRAGVVHRD IKPENILIND RGHVQITDFG LAKAASQATL SSTGMLLGTA 

       190        200        210        220        230        240 
AYLAPEMIEN NQATAQGDLY SVGIMAWEML TGKVPFDSDN PVTLVFKHVH EDVPSVATVC 

       250        260        270        280        290        300 
QGIDPSVAAF IAHLTARQVD ARPTDGAAAA EELSQLAAKL PLEAWQYRLH AEPIGGDHTD 

       310        320        330        340        350        360 
ATAAALVGNI AEQAPLTGVP AGAATFKPSV PAFLADDVAS NTVDTGGAAD VNPPAPPVAP 

       370        380        390        400        410        420 
TTALDSSTPA DASAPHKTQI MAQSGSETQV LPQAGDAFTR ALAFSDEPDV ASNGTGPKKQ 

       430        440        450        460        470        480 
RSKKPLIIVL VIVLVLAAIG GTAGWWWFAG PGSYWSVPKP DDVTCDANAS TECSLAGADW 

       490        500        510        520        530        540 
ATYESTLKAL GIPYKTHKEY SDDVAEGKII SSSVNKTKAV VNSRISKRAN QELTVVVSKG 

       550        560        570        580        590        600 
VRMTTIPKDI LDANSANGKD PLNALKKAGF DNVKHDESKD EYSMDTPQGV ALTISPDPGT 

       610        620        630        640        650        660 
TAKHNDEVTV TLSKGPMPVT MPNIVGKTQD EMQAALGELK LTANVTEQYD DKVEAGQVIS 

       670        680        690        700        710        720 
ASQEAGAQLK WGDSVDVVIS KGPEMATIPS GLVGKQESAV TKTLEGLGFE VKTDKVLGGL 

       730        740        750 
FGTVRTVKSG DTDLSNGGKI RLRDANGNPT VITLTIV 

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References

[1]"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract."
Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.
Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCC 2705.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014295 Genomic DNA. Translation: AAN25222.1.
RefSeqNP_696586.1. NC_004307.2.

3D structure databases

ProteinModelPortalQ8G4G1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING206672.BL1425.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN25222; AAN25222; BL1425.
GeneID1021578.
KEGGblo:BL1425.
PATRIC21117603. VBIBifLon107831_0283.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037187.
KOK00870.
OMARISKRAN.
OrthoDBEOG6B35XT.
PhylomeDBQ8G4G1.

Enzyme and pathway databases

BioCycBLON206672:GI1E-264-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51178. PASTA. 3 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNA2_BIFLO
AccessionPrimary (citable) accession number: Q8G4G1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families