Q8G4D1 (GCP_BIFLO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BL1457

Organism

Bifidobacterium longum (strain NCC 2705)

Taxonomic identifier

206672 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303281

Sequences

	Sequence		Length	Mass (Da)
	Q8G4D1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 9E3158D57867AF08	FASTA	347	36,072
	10 20 30 40 50 60 MSEPVVLGIE STCDETAAAI VRGRELLSNV VASSMEEHAR YGGVIPEIAS RAHAEAFVPC 70 80 90 100 110 120 VSKALVDANM TLADVDAIAV SAGPGLAGCL AVGVSGAKAL AWAANKPIYG INHVIGHIAV 130 140 150 160 170 180 TQLQFGPFPK DTLALIVSGG HTSLLHVEDM PRKIDVVGTT LDDAAGECFD KVARLLGFPY 190 200 210 220 230 240 PGGPHIDRHG QNGDPHAIKV PMGLTQGKAG AAHPYDFSFS GVKTAVARWV ESEQAAGHEI 250 260 270 280 290 300 PVDDVCASLA DSVATVLARK AMRGCRQYDS NTLIVGGGFS ANSQLRAKLL EFGENYGVDV 310 320 330 340 RIPQIKLCTD NGAMVAMLGV NLVEAGVAPS APDFPIDSAM PLTKVSM

References

[1]

"The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract." Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F. Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002) [PubMed: 12381787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCC 2705.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014295 Genomic DNA. Translation: AAN25252.1.
RefSeq	NP_696616.1. NC_004307.2.
3D structure databases
ProteinModelPortal	Q8G4D1.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1021610.
GenomeReviews	Gene locus BL1457 in contig AE014295_GR.
KEGG	blo:BL1457.
NMPDR	fig|206672.1.peg.1383.
PATRIC	21117671. VBIBifLon107831_0317.
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q8G4D1.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BLON206672:BL1457-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BIFLO

Accession

Primary (citable) accession number: Q8G4D1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program