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Protein

Xylose isomerase

Gene

xylA

Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi340Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciBLON206672:G1FZZ-1734-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:BL1704
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000000439 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001957691 – 449Xylose isomeraseAdd BLAST449

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi206672.BL1704

Structurei

3D structure databases

ProteinModelPortaliQ8G3Q1
SMRiQ8G3Q1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
PhylomeDBiQ8G3Q1

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8G3Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLWDVDKIE YVGRAKGPKE DFAFHYYDAD KVVAGKKMKD WLRFGVAWWH
60 70 80 90 100
TFNQELVDPF GTGTAHRPYY KYTDPMDQAL AKVDYAFELF QKLGVEYFCF
110 120 130 140 150
HDRDIAPEGD TLRETNANLD KVVDKIEENM KSTGVKLLWN TSSLFTNPRF
160 170 180 190 200
VSGAATSPFA DIYAYAGGQL KKSLEIGKRL GAENYVFWGG REGYENLWNT
210 220 230 240 250
EMKRETDHIA KFFHMCADYA KEIGFEAQFL IEPKPKEPTL HQYDFDAATA
260 270 280 290 300
IEFLRNHDLT DVFKLNLEGN HANLAGHTYQ HEIRVARESG FLGSLDANQG
310 320 330 340 350
DKLIGWDMDE FPTDLYETVA VMWEVLQAGS IGPHGGLNFD AKPRRTSFYE
360 370 380 390 400
EDLFRSHIAG MDAYAAGLLV ADKMNQDGFI QNLQAERYSS YDSGIGKDID
410 420 430 440
EGNVTLADLE AYSLDKPQSE LIAATKSDHL ESVKATINNY IIDALAEVE
Length:449
Mass (Da):50,868
Last modified:March 1, 2003 - v1
Checksum:i77FB7E971D716CC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA Translation: AAN25490.1
RefSeqiNP_696854.1, NC_004307.2
WP_007053874.1, NC_004307.2

Genome annotation databases

EnsemblBacteriaiAAN25490; AAN25490; BL1704
GeneIDi1021951
KEGGiblo:BL1704
PATRICifig|206672.9.peg.1757

Similar proteinsi

Entry informationi

Entry nameiXYLA_BIFLO
AccessioniPrimary (citable) accession number: Q8G3Q1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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