Reviewed, UniProtKB/Swiss-Prot Q8G3E5 (RECF_BRUSU)

Names and origin

Protein names

Recommended name:
    DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	BR0003

Organism

Brucella suis [Complete proteome] [HAMAP]

Taxonomic identifier

29461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity. HAMAP MF_00365
Subcellular location	Cytoplasm By similarity HAMAP MF_00365.
Sequence similarities	Belongs to the recF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 384	384	DNA replication and repair protein recF HAMAP MF_00365		PRO_0000196401
Regions
	Nucleotide binding	43 – 50	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8G3E5-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 4EDA818CC8B425CC	FASTA	384	41,395
	10 20 30 40 50 60 MEAKDHIERR PDRVSIRRLK LVNFRNYAEL SLPLGPGHVV LTGENGSGKT NLIEAISFLS 70 80 90 100 110 120 PGRGLRRAAY DDVARANAEG GFAIHAALDC MIYGDAEIGT GTAGGGEGGR KVRINGIAAS 130 140 150 160 170 180 ADDLLDYARI LWVVPSMDGL FTGGASDRRR FLDRMVLAID TAHGKRVLDY EKAMRSRNRL 190 200 210 220 230 240 LNDGSNDDQW LDAIENQMAE LGTAIAAARA QAMRLIAAMI ERLPAEGPFP KADCFLEGAL 250 260 270 280 290 300 ESRIGVEAAL DLEEDFRRTL RDGRARDRAA GRTLDGPHRT DLIVQHRPKS MPAALCSTGE 310 320 330 340 350 360 QKALLIGLIL AHARLTAELS GMAPILLLDE IAAHLDMGRR AALFGILDEL GGQAFMTGTD 370 380 RALFDALAGD AQFFNVSAGQ LTGI

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330 / Biovar 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN28961.1.
RefSeq	NP_697046.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1165659.
GenomeReviews	Gene locus BR0003 in contig AE014291_GR.
KEGG	bms:BR0003.
NMPDR	fig|204722.1.peg.3.
TIGR	BR0003.
Phylogenomic databases
HOGENOM	HBG645124.
OMA	NAQGKSN.
PhylomeDB	Q8G3E5.
Enzyme and pathway databases
BioCyc	BSUI204722:BR_0003-MONOMER.
Family and domain databases
HAMAP	MF_00365. RecF. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001238. DNA-binding_RecF. IPR018078. DNA-binding_RecF_CS. IPR003395. RecF/RecN/SMC_N. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_BRUSU

Accession

Primary (citable) accession number: Q8G3E5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 7, 2003
Last sequence update:	March 1, 2003
Last modified:	January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)