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Q8G3C3 (KCY_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytidylate kinase

Short name=CK
EC=2.7.4.25
Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase
Gene names
Name:cmk
Ordered Locus Names:BR0026, BS1330_I0026
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (d)CMP = ADP + (d)CDP. HAMAP-Rule MF_00238

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00238.

Sequence similarities

Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpyrimidine nucleotide metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

cytidylate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Cytidylate kinase HAMAP-Rule MF_00238
PRO_0000131892

Regions

Nucleotide binding15 – 239ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8G3C3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 0069E1E2F7C205A4

FASTA21923,402
        10         20         30         40         50         60 
MKSFVVAPFI VAIDGPAASG KGTLARRIAT HYGMPHLDTG LTYRAVAKAL LDKGLSLDDE 

        70         80         90        100        110        120 
ALATDAALSL DLLAMDKAVL SAHAIGEAAS KVAVMPAVRR ALVEAQRHFA NALPSSVLDG 

       130        140        150        160        170        180 
RDIGTVVCPD AAIKLFVTAS PEVRARRRFD EVLARGDTAD FAEILADLKK RDERDMNRTD 

       190        200        210 
SPLRPAEDAH LLDTSEMSIE AAFLAAKKLI DHALAQHRG 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN28983.1.
CP002997 Genomic DNA. Translation: AEM17395.1.
RefSeqNP_697068.1. NC_004310.3.
YP_005614887.1. NC_017251.1.

3D structure databases

ProteinModelPortalQ8G3C3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR0026.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN28983; AAN28983; BR0026.
AEM17395; AEM17395; BS1330_I0026.
GeneID1165683.
12137240.
KEGGbms:BR0026.
bsi:BS1330_I0026.
PATRIC17788311. VBIBruSui107850_0029.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0283.
HOGENOMHOG000242849.
KOK00945.
OMAHIDTGAM.
OrthoDBEOG6WDSMP.
ProtClustDBPRK00023.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00238. Cytidyl_kinase_type1.
InterProIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR21299:SF2. PTHR21299:SF2. 1 hit.
PfamPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00017. cmk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKCY_BRUSU
AccessionPrimary (citable) accession number: Q8G3C3
Secondary accession number(s): G0KAJ8
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names