SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8G3B2

- KDSB_BRUSU

UniProt

Q8G3B2 - KDSB_BRUSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

3-deoxy-manno-octulosonate cytidylyltransferase

Gene
kdsB, BR0038, BS1330_I0038
Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria By similarity.UniRule annotation

Catalytic activityi

CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 3-deoxy-manno-octulosonate cytidylyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-UniPathway
  2. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00030.
UPA00358; UER00476.

Names & Taxonomyi

Protein namesi
Recommended name:
3-deoxy-manno-octulosonate cytidylyltransferase (EC:2.7.7.38)
Alternative name(s):
CMP-2-keto-3-deoxyoctulosonic acid synthase
Short name:
CKS
Short name:
CMP-KDO synthase
Gene namesi
Name:kdsB
Ordered Locus Names:BR0038, BS1330_I0038
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2512513-deoxy-manno-octulosonate cytidylyltransferaseUniRule annotationPRO_0000370017Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR0038.

Structurei

3D structure databases

ProteinModelPortaliQ8G3B2.

Family & Domainsi

Sequence similaritiesi

Belongs to the KdsB family.

Phylogenomic databases

eggNOGiCOG1212.
HOGENOMiHOG000007602.
KOiK00979.
OMAiDDQRIAD.
OrthoDBiEOG6KT2SK.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
HAMAPiMF_00057. CMP_KDO_synth.
InterProiIPR003329. Cytidylyl_trans.
IPR004528. KdsB.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PANTHERiPTHR21485:SF4. PTHR21485:SF4. 1 hit.
PfamiPF02348. CTP_transf_3. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR00466. kdsB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8G3B2-1 [UniParc]FASTAAdd to Basket

« Hide

MLQTMKTLTL IPTRLGSTRL PNKPLADICG KPMIVHVADR AAAAKLGRTV    50
IATDSEEIFK VVAAHGHEAI MTRGDHESGS DRIYEALAKL DPSGEIDAVV 100
NVQGDLPTID PDTIRRALLP LEDGPADIAT LGVEITVEEE KTNPNVVKIV 150
GSPLAGNRRL RALYFTRATA PYGEGPLYHH IGLYAYRRSA LERFVKLGPS 200
PLEKREKLEQ LRALEAGMRI DVEIVKTVPL GVDTQADLDR ARTFCSQAGT 250
I 251
Length:251
Mass (Da):27,334
Last modified:March 1, 2003 - v1
Checksum:i8EFDB1A32037C2B6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN28995.1.
CP002997 Genomic DNA. Translation: AEM17407.1.
RefSeqiNP_697080.1. NC_004310.3.
YP_005614899.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN28995; AAN28995; BR0038.
AEM17407; AEM17407; BS1330_I0038.
GeneIDi1165695.
12137252.
KEGGibms:BR0038.
bsi:BS1330_I0038.
PATRICi17788337. VBIBruSui107850_0042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN28995.1 .
CP002997 Genomic DNA. Translation: AEM17407.1 .
RefSeqi NP_697080.1. NC_004310.3.
YP_005614899.1. NC_017251.1.

3D structure databases

ProteinModelPortali Q8G3B2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR0038.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN28995 ; AAN28995 ; BR0038 .
AEM17407 ; AEM17407 ; BS1330_I0038 .
GeneIDi 1165695.
12137252.
KEGGi bms:BR0038.
bsi:BS1330_I0038.
PATRICi 17788337. VBIBruSui107850_0042.

Phylogenomic databases

eggNOGi COG1212.
HOGENOMi HOG000007602.
KOi K00979.
OMAi DDQRIAD.
OrthoDBi EOG6KT2SK.

Enzyme and pathway databases

UniPathwayi UPA00030 .
UPA00358 ; UER00476 .

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
HAMAPi MF_00057. CMP_KDO_synth.
InterProi IPR003329. Cytidylyl_trans.
IPR004528. KdsB.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
PANTHERi PTHR21485:SF4. PTHR21485:SF4. 1 hit.
Pfami PF02348. CTP_transf_3. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
TIGRFAMsi TIGR00466. kdsB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiKDSB_BRUSU
AccessioniPrimary (citable) accession number: Q8G3B2
Secondary accession number(s): G0KAL0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi