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Q8G2W6 (CYSD_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sulfate adenylyltransferase subunit 2

EC=2.7.7.4
Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT
Gene names
Name:cysD
Ordered Locus Names:BR0193, BS1330_I0193
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length300 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP-Rule MF_00064

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP-Rule MF_00064

Subunit structure

Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.

Sequence similarities

Belongs to the PAPS reductase family. CysD subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 300300Sulfate adenylyltransferase subunit 2 HAMAP-Rule MF_00064
PRO_0000340187

Sequences

Sequence LengthMass (Da)Tools
Q8G2W6 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: A2EC938F2C141D7A

FASTA30034,743
        10         20         30         40         50         60 
MKNLTHLQRL EAEAIHVFRE VAATFSNPVM LYSVGKDSSV MLHLAMKAFY PAPPPFPFLH 

        70         80         90        100        110        120 
VDTTWKFREM IEFRDAQARE KGFELLVHVN EQGVRDGIGP FTHGSNVHTH IMKTVGLRQA 

       130        140        150        160        170        180 
LDKYRFDAAF GGARRDEEKS RAKERIFSFR NAQHGWDPKN QRPEMWKIYN TRVSKGESIR 

       190        200        210        220        230        240 
VFPLSNWTEL DIWQYILQEN IPIVPLYFAA RRPVVERDGM LIMVDDDRMK LRPGEQVENR 

       250        260        270        280        290        300 
LVRFRTLGCY PLTGAIPSSA ANLSDIVEEM LIARTSERQG RAIDRDEAGS MEKKKREGYF 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN29146.1.
CP002997 Genomic DNA. Translation: AEM17558.1.
RefSeqNP_697231.1. NC_004310.3.
YP_005615050.1. NC_017251.1.

3D structure databases

ProteinModelPortalQ8G2W6.
SMRQ8G2W6. Positions 4-210.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR0193.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN29146; AAN29146; BR0193.
AEM17558; AEM17558; BS1330_I0193.
GeneID1165850.
12138734.
KEGGbms:BR0193.
bsi:BS1330_I0193.
PATRIC17788656. VBIBruSui107850_0201.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0175.
HOGENOMHOG000263604.
KOK00957.
OMAWQYIHLE.
OrthoDBEOG6W45TZ.
ProtClustDBPRK05253.

Enzyme and pathway databases

UniPathwayUPA00140; UER00204.

Family and domain databases

Gene3D3.40.50.620. 2 hits.
HAMAPMF_00064. Sulf_adenylyltr_sub2.
InterProIPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
IPR011784. SO4_adenylTrfase_ssu.
[Graphical view]
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFPIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMsTIGR02039. CysD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYSD_BRUSU
AccessionPrimary (citable) accession number: Q8G2W6
Secondary accession number(s): G0KBG6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella suis

Brucella suis (strain 1330): entries and gene names