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Protein

Translation initiation factor IF-1

Gene

infA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3.UniRule annotation

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-1UniRule annotation
Gene namesi
Name:infAUniRule annotation
Ordered Locus Names:BR0249, BS1330_I0250
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7272Translation initiation factor IF-1PRO_0000095755Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR0249.

Structurei

3D structure databases

ProteinModelPortaliQ8G2R5.
SMRiQ8G2R5. Positions 2-70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7272S1-likeUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the IF-1 family.UniRule annotation
Contains 1 S1-like domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0361.
HOGENOMiHOG000221323.
KOiK02518.
OMAiMAKQKHI.
OrthoDBiEOG6384SC.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00075. IF_1.
InterProiIPR012340. NA-bd_OB-fold.
IPR006196. RNA-binding_domain_S1_IF1.
IPR022967. S1_dom.
IPR004368. TIF_IF1.
[Graphical view]
PfamiPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00008. infA. 1 hit.
PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G2R5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKEEVLEFP GVVTELLPNA MFRVKLENEH EIIAHTAGRM RKNRIRVLAG
60 70
DKVLVEMTPY DLTKGRITYR LK
Length:72
Mass (Da):8,338
Last modified:March 1, 2003 - v1
Checksum:i67DFD20EB09AE093
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN29198.1.
CP002997 Genomic DNA. Translation: AEM17611.1.
RefSeqiNP_697283.1. NC_004310.3.
YP_005615103.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN29198; AAN29198; BR0249.
AEM17611; AEM17611; BS1330_I0250.
GeneIDi1165908.
12138793.
KEGGibms:BR0249.
bsi:BS1330_I0250.
PATRICi17788775. VBIBruSui107850_0258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN29198.1.
CP002997 Genomic DNA. Translation: AEM17611.1.
RefSeqiNP_697283.1. NC_004310.3.
YP_005615103.1. NC_017251.1.

3D structure databases

ProteinModelPortaliQ8G2R5.
SMRiQ8G2R5. Positions 2-70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi204722.BR0249.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN29198; AAN29198; BR0249.
AEM17611; AEM17611; BS1330_I0250.
GeneIDi1165908.
12138793.
KEGGibms:BR0249.
bsi:BS1330_I0250.
PATRICi17788775. VBIBruSui107850_0258.

Phylogenomic databases

eggNOGiCOG0361.
HOGENOMiHOG000221323.
KOiK02518.
OMAiMAKQKHI.
OrthoDBiEOG6384SC.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00075. IF_1.
InterProiIPR012340. NA-bd_OB-fold.
IPR006196. RNA-binding_domain_S1_IF1.
IPR022967. S1_dom.
IPR004368. TIF_IF1.
[Graphical view]
PfamiPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00008. infA. 1 hit.
PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiIF1_BRUSU
AccessioniPrimary (citable) accession number: Q8G2R5
Secondary accession number(s): G0KBU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. Translation initiation factors
    List of translation initiation factor entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.