Q8G2R5 (IF1_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-1

Gene names

Name:	infA
Ordered Locus Names:	BR0249, BS1330_I0250

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity. HAMAP-Rule MF_00075
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the IF-1 family. Contains 1 S1-like domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 72	72	Translation initiation factor IF-1 HAMAP-Rule MF_00075		PRO_0000095755
Regions
	Domain	1 – 72	72	S1-like

Sequences

	Sequence		Length	Mass (Da)
	Q8G2R5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 67DFD20EB09AE093	FASTA	72	8,338
	10 20 30 40 50 60 MAKEEVLEFP GVVTELLPNA MFRVKLENEH EIIAHTAGRM RKNRIRVLAG DKVLVEMTPY 70 DLTKGRITYR LK

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN29198.1. CP002997 Genomic DNA. Translation: AEM17611.1.
RefSeq	NP_697283.1. NC_004310.3. YP_005615103.1. NC_017251.1.
3D structure databases
ProteinModelPortal	Q8G2R5.
SMR	Q8G2R5. Positions 2-70.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BR0249.
Proteomic databases
ProMEX	Q8G2R5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN29198; AAN29198; BR0249. AEM17611; AEM17611; BS1330_I0250.
GeneID	1165908. 12138793.
KEGG	bms:BR0249. bsi:BS1330_I0250.
PATRIC	17788775. VBIBruSui107850_0258.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0361.
HOGENOM	HOG000221323.
KO	K02518.
OMA	KEDSIEM.
ProtClustDB	PRK00276.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
HAMAP	MF_00075. IF-1.
InterPro	IPR012340. NA-bd_OB-fold. IPR022967. RNA-binding_domain_S1. IPR006196. RNA-binding_domain_S1_IF1. IPR004368. TIF_IF1. [Graphical view]
Pfam	PF01176. eIF-1a. 1 hit. [Graphical view]
SMART	SM00316. S1. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00008. infA. 1 hit.
PROSITE	PS50832. S1_IF1_TYPE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF1_BRUSU

Accession

Primary (citable) accession number: Q8G2R5
Secondary accession number(s): G0KBU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program