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Q8G2R5 (IF1_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-1
Gene names
Name:infA
Ordered Locus Names:BR0249, BS1330_I0250
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length72 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity. HAMAP-Rule MF_00075

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00075.

Sequence similarities

Belongs to the IF-1 family.

Contains 1 S1-like domain.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7272Translation initiation factor IF-1 HAMAP-Rule MF_00075
PRO_0000095755

Regions

Domain1 – 7272S1-like

Sequences

Sequence LengthMass (Da)Tools
Q8G2R5 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 67DFD20EB09AE093

FASTA728,338
        10         20         30         40         50         60 
MAKEEVLEFP GVVTELLPNA MFRVKLENEH EIIAHTAGRM RKNRIRVLAG DKVLVEMTPY 

        70 
DLTKGRITYR LK 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN29198.1.
CP002997 Genomic DNA. Translation: AEM17611.1.
RefSeqNP_697283.1. NC_004310.3.
YP_005615103.1. NC_017251.1.

3D structure databases

ProteinModelPortalQ8G2R5.
SMRQ8G2R5. Positions 2-70.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR0249.

Proteomic databases

ProMEXQ8G2R5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN29198; AAN29198; BR0249.
AEM17611; AEM17611; BS1330_I0250.
GeneID1165908.
12138793.
KEGGbms:BR0249.
bsi:BS1330_I0250.
PATRIC17788775. VBIBruSui107850_0258.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0361.
HOGENOMHOG000221323.
KOK02518.
OMARITFRAK.
OrthoDBEOG6384SC.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00075. IF_1.
InterProIPR012340. NA-bd_OB-fold.
IPR022967. RNA-binding_domain_S1.
IPR006196. RNA-binding_domain_S1_IF1.
IPR004368. TIF_IF1.
[Graphical view]
PfamPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTSM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00008. infA. 1 hit.
PROSITEPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF1_BRUSU
AccessionPrimary (citable) accession number: Q8G2R5
Secondary accession number(s): G0KBU8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries

Brucella suis

Brucella suis (strain 1330): entries and gene names