Reviewed,
UniProtKB/Swiss-Prot Q8G2N3 (G6PI_BRUSU)
Last modified
November 24, 2009.
Version 38.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Glucose-6-phosphate isomerase Short name=GPI EC=5.3.1.9 Alternative name(s): Phosphoglucose isomerase Short name=PGI Phosphohexose isomerase Short name=PHI | ||||
| Gene names |
| ||||
| Organism | Brucella suis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 29461 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella |
Protein attributes
| Sequence length | 549 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473 |
| Pathway | Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473 |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the GPI family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Gluconeogenesis Glycolysis |
| Cellular component | Cytoplasm |
| Molecular function | Isomerase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysisInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 549 | 549 | Glucose-6-phosphate isomerase HAMAP MF_00473 | PRO_0000180610 | |||||
Sites | |||||||||
| Active site | 353 | 1 | Proton donor By similarity | ||||||
| Active site | 384 | 1 | By similarity | ||||||
| Active site | 513 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. Fraser C.M.Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330 / Biovar 1. |
Cross-references
Sequence databases | |
|---|---|
| AE014291 Genomic DNA. Translation: AAN29234.1. | |
| RefSeq | NP_697319.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1165946. |
| GenomeReviews | Gene locus BR0285 in contig AE014291_GR. |
| KEGG | bms:BR0285. |
| NMPDR | fig|204722.1.peg.276. |
| TIGR | BR0285. |
Phylogenomic databases | |
| HOGENOM | Q8G2N3. |
| OMA | MRDWFSK |
Enzyme and pathway databases | |
| BioCyc | BSUI204722:BR_0285-MON. |
| BRENDA | 5.3.1.9. 281610. |
Family and domain databases | |
| HAMAP | MF_00473. [Tree] |
| InterPro | IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view] |
| PANTHER | PTHR11469. G6P_Isomerase. 1 hit. |
| Pfam | PF00342. PGI. 1 hit. [Graphical view] |
| PRINTS | PR00662. G6PISOMERASE. |
| PROSITE | PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | G6PI_BRUSU | ||||||||
| Accession | Primary (citable) accession number: Q8G2N3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Brucella suis Brucella suis (strain 1330): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


