Q8G2K0 (Q8G2K0_BRUSU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinate synthase EMBL AEM17681.1
EC=2.3.1.37 EMBL AEM17681.1

Submitted name:
5-aminolevulinic acid synthase EMBL AAN29268.1
EC=2.3.1.37 EMBL AAN29268.1

Gene names

Name:	hemA EMBL AAN29268.1
Ordered Locus Names:	BR0319, BS1330_I0320 EMBL AEM17681.1

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Acyltransferase EMBL AAN29268.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8G2K0 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 9C2126CEAB916A8A	FASTA	425	46,137
	10 20 30 40 50 60 MDYRRFFEEA IDQLHAEKRY RVFADLERIV GRFPQAIWRN NGTAREITVW CSNDYLGMGH 70 80 90 100 110 120 HPDVIKAMCE TAGSAGSGAG GTRNISGNNH PLVELESELA DLHGKEAGLV FTSGFVSNEA 130 140 150 160 170 180 SISTIARLLP NCLILSDELN HASMIEGVRH SGAEKKIFRH NDVEHLEQLL KAADRSRAKL 190 200 210 220 230 240 IVFESVYSMD GDIAPIEKIA DLADKYNAMT YIDEVHAVGM YGAHGGGITE RDGLAHRIDI 250 260 270 280 290 300 IEGTLAKAFG ALGGYITGSR AIIDAVRSYA PGFIFTTSLP PAVAAAATAA IRHLKSSQAE 310 320 330 340 350 360 RDGQQRQAQR AKDVLSAAGL PVMPSQTHIV PILVGDPELC KKASDRLLEV HGIYIQPINY 370 380 390 400 410 420 PTVPRGTERL RITPSPLHDD KLIDGLKDAL LEVWNELGIP FAEPSAPQAA NSDRIIPLMV SKAGG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.
[2]	"Revised Genome Sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) Cited for: NUCLEOTIDE SEQUENCE. Strain: 1330 EMBL AEM17681.1.
[3]	"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed: 22038969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN29268.1. CP002997 Genomic DNA. Translation: AEM17681.1.
RefSeq	NP_697353.1. NC_004310.3.
3D structure databases
HSSP	HSSP built from PDB template 1FC4 based on UniProtKB P07912.
ProteinModelPortal	Q8G2K0.
SMR	Q8G2K0. Positions 2-394.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1165980.
GenomeReviews	Gene locus BR0319 in contig AE014291_GR.
KEGG	bms:BR0319.
NMPDR	fig|204722.1.peg.310.
PATRIC	17788927. VBIBruSui107850_0332.
TIGR	BR0319.
Phylogenomic databases
HOGENOM	HBG649839.
OMA	HLKESNE.
PhylomeDB	Q8G2K0.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8G2K0_BRUSU

Accession

Primary (citable) accession number: Q8G2K0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)