Reviewed, UniProtKB/Swiss-Prot Q8G2D9 (ATPF1_BRUSU)

Names and origin

Protein names

Recommended name:
    ATP synthase subunit b 1
Alternative name(s):
    ATP synthase F(0) sector subunit b 1
    F-type ATPase subunit b 1
      Short name=F-ATPase subunit b 1
    ATPase subunit I 1

Gene names

Name:	atpF1
Ordered Locus Names:	BR0384

Organism

Brucella suis [Complete proteome] [HAMAP]

Taxonomic identifier

29461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation By similarity. Component of the F0 channel, it forms part of the peripheral stalk, linking F1 to F0 By similarity.
Subunit structure	F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the ATPase B chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 208	208	ATP synthase subunit b 1 HAMAP MF_01398		PRO_0000368374
Regions
	Transmembrane	56 – 78	23	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8G2D9-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 0EE57A31D20BC6E8	FASTA	208	21,896
	10 20 30 40 50 60 MFVSTAFAQT ATESQPASTA GEHGAADAVH TETGVAHDAG HGSGVFPPFD STHYASQVLW 70 80 90 100 110 120 LAITFGLFYL FLSRVVLPRI GGVIETRRDR IAQDLEQAAR LKQDADNAIA AYEQELAQAR 130 140 150 160 170 180 SKAASIAEAA REKGKGEADA ERASAEAVLE SKLKEAEERI AAIKAKAMSD VGNIAEETTA 190 200 TIVEQLLGLT ADKASVSEAV KAIRASNA

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014291 Genomic DNA. Translation: AAN29330.1.
RefSeq	NP_697415.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1166045.
GenomeReviews	Gene locus BR0384 in contig AE014291_GR.
KEGG	bms:BR0384.
TIGR	BR0384.
Phylogenomic databases
HOGENOM	Q8G2D9.
OMA	KRSGTID
Enzyme and pathway databases
BioCyc	BSUI204722:BR_0384-MON.
Family and domain databases
HAMAP	MF_01398. [Tree]
InterPro	IPR002146. ATPase_F0-cplx_b/b'su_bac. [Graphical view]
Pfam	PF00430. ATP-synt_B. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPF1_BRUSU

Accession

Primary (citable) accession number: Q8G2D9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 1, 2003
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)