Reviewed, UniProtKB/Swiss-Prot Q8G261 (COXZ_BRUSU)

Names and origin

Protein names

Recommended name:
    Cytochrome c oxidase assembly protein ctaG

Gene names

Name:	ctaG
Ordered Locus Names:	BR0471

Organism

Brucella suis [Complete proteome] [HAMAP]

Taxonomic identifier

29461 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity.
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential.
Sequence similarities	Belongs to the COX11/ctaG family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane
Ligand	Copper
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	respiratory chain complex IV assembly Inferred from electronic annotation. Source: HAMAP
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: HAMAP
Molecular function	copper ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Cytochrome c oxidase assembly protein ctaG HAMAP MF_00155		PRO_0000206034
Regions
	Topological domain	1 – 12	12	Cytoplasmic Potential
	Transmembrane	13 – 35	23	Signal-anchor for type II membrane protein Potential
	Topological domain	36 – 201	166	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8G261-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 64ED1CCF119944A6	FASTA	201	22,472
	10 20 30 40 50 60 MTDQGENEKK QRRSNATIAV ACLSFFVCMI GAAYASVPLY RIFCQVTGYG GTTQRVEQYS 70 80 90 100 110 120 DTILDKTIKV RFDANIANGL PWDFKPMQRE VTVRIGETTM IKYEAHNLFG EETYGRASFN 130 140 150 160 170 180 VAPGRAGAYF NKVECFCFTD NTLKPGEDLE LPVVFFVDPE FVNDPDLKDV KTITLSYTFF 190 200 PIDKPRPVVN AKAVGSTRNG G

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014291 Genomic DNA. Translation: AAN29414.1.
RefSeq	NP_697499.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1166132.
GenomeReviews	Gene locus BR0471 in contig AE014291_GR.
KEGG	bms:BR0471.
NMPDR	fig|204722.1.peg.456.
TIGR	BR0471.
Phylogenomic databases
HOGENOM	Q8G261.
OMA	PVSFYID
Enzyme and pathway databases
BioCyc	BSUI204722:BR_0471-MON.
Family and domain databases
HAMAP	MF_00155. [Tree]
InterPro	IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COXZ_BRUSU

Accession

Primary (citable) accession number: Q8G261

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2003
Last sequence update:	March 1, 2003
Last modified:	November 24, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)