Q8G261 (COXZ_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG

Gene names

Name:	ctaG
Ordered Locus Names:	BR0471, BS1330_I0472

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Ligand	Copper
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155		PRO_0000206034
Regions
	Topological domain	1 – 12	12	Cytoplasmic Potential
	Transmembrane	13 – 35	23	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	36 – 201	166	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8G261 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 64ED1CCF119944A6	FASTA	201	22,472
	10 20 30 40 50 60 MTDQGENEKK QRRSNATIAV ACLSFFVCMI GAAYASVPLY RIFCQVTGYG GTTQRVEQYS 70 80 90 100 110 120 DTILDKTIKV RFDANIANGL PWDFKPMQRE VTVRIGETTM IKYEAHNLFG EETYGRASFN 130 140 150 160 170 180 VAPGRAGAYF NKVECFCFTD NTLKPGEDLE LPVVFFVDPE FVNDPDLKDV KTITLSYTFF 190 200 PIDKPRPVVN AKAVGSTRNG G

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed: 22038969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN29414.1. CP002997 Genomic DNA. Translation: AEM17827.1.
RefSeq	NP_697499.1. NC_004310.3.
3D structure databases
ProteinModelPortal	Q8G261.
SMR	Q8G261. Positions 56-181.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1166132.
GenomeReviews	Gene locus BR0471 in contig AE014291_GR.
KEGG	bms:BR0471.
NMPDR	fig|204722.1.peg.456.
PATRIC	17789236. VBIBruSui107850_0486.
TIGR	BR0471.
Phylogenomic databases
HOGENOM	HBG525908.
OMA	KLIFYRA.
PhylomeDB	Q8G261.
ProtClustDB	PRK05089.
Enzyme and pathway databases
BioCyc	BSUI204722:BR_0471-MONOMER.
Family and domain databases
HAMAP	MF_00155. CtaG. [Tree]
InterPro	IPR023471. CtaG/Cox11_dom. IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
KO	K02258.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
SUPFAM	SSF110111. CtaG_Cox11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COXZ_BRUSU

Accession

Primary (citable) accession number: Q8G261
Secondary accession number(s): G0K720

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program