Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8G204

- XYLA_BRUSU

UniProt

Q8G204 - XYLA_BRUSU

Protein

Xylose isomerase

Gene

xylA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei100 – 1001UniRule annotation
    Active sitei103 – 1031UniRule annotation
    Metal bindingi231 – 2311Magnesium 1UniRule annotation
    Metal bindingi267 – 2671Magnesium 1UniRule annotation
    Metal bindingi267 – 2671Magnesium 2UniRule annotation
    Metal bindingi270 – 2701Magnesium 2UniRule annotation
    Metal bindingi295 – 2951Magnesium 1UniRule annotation
    Metal bindingi306 – 3061Magnesium 2UniRule annotation
    Metal bindingi308 – 3081Magnesium 2UniRule annotation
    Metal bindingi338 – 3381Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shunt, Xylose metabolism

    Keywords - Ligandi

    Magnesium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    Ordered Locus Names:BR0547, BS1330_I0543
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 435435Xylose isomerasePRO_0000195772Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi204722.BR0547.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8G204.
    SMRiQ8G204. Positions 4-435.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2115.
    HOGENOMiHOG000252293.
    KOiK01805.
    OMAiLFHAHIG.
    OrthoDBiEOG62NX4R.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8G204-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTGFFGDIQ KVRYEGPESD NPLAFRHYNA DEIVLGKRME DHLRFAVAYW    50
    HSFAWEGGDP FGGRTFDRPW FSNEIDAAKL KADVAFEFFS LLGAPYYCFH 100
    DADVRPEGRN FAENTRYLNE IVDIFEKKQA ETGMKLLWGT ANLFSNRRYM 150
    AGAATNPDPD VFAFAAATVK TCIDATKRLG GENYVLWGGR EGYETLLNTD 200
    LSRELDHMGR FLSLVVEYKH KIGFKGTILI EPKPQEPTKH QYDYDVATVY 250
    GFLKRYGLEN EVKVNIEQGH AILAGHSFEH ELALARTLGI FGSIDMNRND 300
    YQSGWDTDQF PNNVPEMALA YYQVLLAGGF TTGGTNFDAK LRRQSLDSQD 350
    LLIGHIGGMD CCARGLKAAA RMLEDGALSK PLDERYAGWN GEFGKRLLSG 400
    LSLDQIAGEV EAKDINPQPK SGRQEYLENI VNHYV 435
    Length:435
    Mass (Da):48,975
    Last modified:March 1, 2003 - v1
    Checksum:i0F59B03FE726E6E0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN29478.1.
    CP002997 Genomic DNA. Translation: AEM17895.1.
    RefSeqiNP_697563.1. NC_004310.3.
    YP_005615387.1. NC_017251.1.

    Genome annotation databases

    EnsemblBacteriaiAAN29478; AAN29478; BR0547.
    AEM17895; AEM17895; BS1330_I0543.
    GeneIDi1166209.
    12136863.
    KEGGibms:BR0547.
    bsi:BS1330_I0543.
    PATRICi17789395. VBIBruSui107850_0565.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN29478.1 .
    CP002997 Genomic DNA. Translation: AEM17895.1 .
    RefSeqi NP_697563.1. NC_004310.3.
    YP_005615387.1. NC_017251.1.

    3D structure databases

    ProteinModelPortali Q8G204.
    SMRi Q8G204. Positions 4-435.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BR0547.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN29478 ; AAN29478 ; BR0547 .
    AEM17895 ; AEM17895 ; BS1330_I0543 .
    GeneIDi 1166209.
    12136863.
    KEGGi bms:BR0547.
    bsi:BS1330_I0543.
    PATRICi 17789395. VBIBruSui107850_0565.

    Phylogenomic databases

    eggNOGi COG2115.
    HOGENOMi HOG000252293.
    KOi K01805.
    OMAi LFHAHIG.
    OrthoDBi EOG62NX4R.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiXYLA_BRUSU
    AccessioniPrimary (citable) accession number: Q8G204
    Secondary accession number(s): G0K7G7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3