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Protein

Xylose isomerase

Gene

xylA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100UniRule annotation1
Active sitei103UniRule annotation1
Metal bindingi231Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 2UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi295Magnesium 1UniRule annotation1
Metal bindingi306Magnesium 2UniRule annotation1
Metal bindingi308Magnesium 2UniRule annotation1
Metal bindingi338Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:BR0547, BS1330_I0543
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001957721 – 435Xylose isomeraseAdd BLAST435

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8G204
SMRiQ8G204
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8G204-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTGFFGDIQ KVRYEGPESD NPLAFRHYNA DEIVLGKRME DHLRFAVAYW
60 70 80 90 100
HSFAWEGGDP FGGRTFDRPW FSNEIDAAKL KADVAFEFFS LLGAPYYCFH
110 120 130 140 150
DADVRPEGRN FAENTRYLNE IVDIFEKKQA ETGMKLLWGT ANLFSNRRYM
160 170 180 190 200
AGAATNPDPD VFAFAAATVK TCIDATKRLG GENYVLWGGR EGYETLLNTD
210 220 230 240 250
LSRELDHMGR FLSLVVEYKH KIGFKGTILI EPKPQEPTKH QYDYDVATVY
260 270 280 290 300
GFLKRYGLEN EVKVNIEQGH AILAGHSFEH ELALARTLGI FGSIDMNRND
310 320 330 340 350
YQSGWDTDQF PNNVPEMALA YYQVLLAGGF TTGGTNFDAK LRRQSLDSQD
360 370 380 390 400
LLIGHIGGMD CCARGLKAAA RMLEDGALSK PLDERYAGWN GEFGKRLLSG
410 420 430
LSLDQIAGEV EAKDINPQPK SGRQEYLENI VNHYV
Length:435
Mass (Da):48,975
Last modified:March 1, 2003 - v1
Checksum:i0F59B03FE726E6E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA Translation: AAN29478.1
CP002997 Genomic DNA Translation: AEM17895.1
RefSeqiWP_006189966.1, NZ_KN046804.1

Genome annotation databases

EnsemblBacteriaiAAN29478; AAN29478; BR0547
AEM17895; AEM17895; BS1330_I0543
KEGGibms:BR0547
bsi:BS1330_I0543
PATRICifig|204722.21.peg.2838

Similar proteinsi

Entry informationi

Entry nameiXYLA_BRUSU
AccessioniPrimary (citable) accession number: Q8G204
Secondary accession number(s): G0K7G7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health