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Q8G1Z7

- BETI_BRUSU

UniProt

Q8G1Z7 - BETI_BRUSU

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Protein

HTH-type transcriptional regulator BetI

Gene

betI

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).By similarity

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi31 – 5020H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycine betaine biosynthetic process from choline Source: UniProtKB-HAMAP
  2. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

UniPathwayiUPA00529.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator BetIUniRule annotation
Gene namesi
Name:betIUniRule annotation
Ordered Locus Names:BR0554, BS1330_I0550
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198HTH-type transcriptional regulator BetIPRO_0000070579Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR0554.

Structurei

3D structure databases

ProteinModelPortaliQ8G1Z7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 6861HTH tetR-typeUniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1309.
HOGENOMiHOG000248227.
KOiK02167.
OMAiGIINHYF.
OrthoDBiEOG6FFS5N.

Family and domain databases

Gene3Di1.10.357.10. 1 hit.
HAMAPiMF_00768. HTH_type_BetI.
InterProiIPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
IPR017757. Tscrpt_rep_BetI.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
TIGRFAMsiTIGR03384. betaine_BetI. 1 hit.
PROSITEiPS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G1Z7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPKIGMEPLR RRELIDAAIR TIGQRGSLDV TVAQIAHEAG VSPALAHHYF
60 70 80 90 100
GGKDKLILAT MRHLLRELGR DLNAAIKQAN APHERIAAII AVNFSAAQFA
110 120 130 140 150
QETIAAWLTF YVHAQQSDDI KRLLRIYARR LHSNLVFALE QLTSRARANR
160 170 180 190
IAEGAGAMID GLYIRHALGA DAPDAASAIA LVEDYIAIQL SGQPSAEN
Length:198
Mass (Da):21,590
Last modified:March 1, 2003 - v1
Checksum:iBC8AF3275FC875EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN29485.1.
CP002997 Genomic DNA. Translation: AEM17902.1.
RefSeqiNP_697570.1. NC_004310.3.
YP_005615394.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN29485; AAN29485; BR0554.
AEM17902; AEM17902; BS1330_I0550.
GeneIDi1166216.
12136870.
KEGGibms:BR0554.
bsi:BS1330_I0550.
PATRICi17789407. VBIBruSui107850_0571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN29485.1 .
CP002997 Genomic DNA. Translation: AEM17902.1 .
RefSeqi NP_697570.1. NC_004310.3.
YP_005615394.1. NC_017251.1.

3D structure databases

ProteinModelPortali Q8G1Z7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR0554.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN29485 ; AAN29485 ; BR0554 .
AEM17902 ; AEM17902 ; BS1330_I0550 .
GeneIDi 1166216.
12136870.
KEGGi bms:BR0554.
bsi:BS1330_I0550.
PATRICi 17789407. VBIBruSui107850_0571.

Phylogenomic databases

eggNOGi COG1309.
HOGENOMi HOG000248227.
KOi K02167.
OMAi GIINHYF.
OrthoDBi EOG6FFS5N.

Enzyme and pathway databases

UniPathwayi UPA00529 .

Family and domain databases

Gene3Di 1.10.357.10. 1 hit.
HAMAPi MF_00768. HTH_type_BetI.
InterProi IPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
IPR017757. Tscrpt_rep_BetI.
[Graphical view ]
Pfami PF00440. TetR_N. 1 hit.
[Graphical view ]
PRINTSi PR00455. HTHTETR.
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
TIGRFAMsi TIGR03384. betaine_BetI. 1 hit.
PROSITEi PS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiBETI_BRUSU
AccessioniPrimary (citable) accession number: Q8G1Z7
Secondary accession number(s): G0K7H4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3