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Q8G1Z7 (BETI_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
HTH-type transcriptional regulator BetI
Gene names
Name:betI
Ordered Locus Names:BR0554, BS1330_I0550
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine By similarity. HAMAP-Rule MF_00768

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway [regulation]. HAMAP-Rule MF_00768

Sequence similarities

Contains 1 HTH tetR-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198HTH-type transcriptional regulator BetI HAMAP-Rule MF_00768
PRO_0000070579

Regions

Domain8 – 6861HTH tetR-type
DNA binding31 – 5020H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8G1Z7 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: BC8AF3275FC875EA

FASTA19821,590
        10         20         30         40         50         60 
MPKIGMEPLR RRELIDAAIR TIGQRGSLDV TVAQIAHEAG VSPALAHHYF GGKDKLILAT 

        70         80         90        100        110        120 
MRHLLRELGR DLNAAIKQAN APHERIAAII AVNFSAAQFA QETIAAWLTF YVHAQQSDDI 

       130        140        150        160        170        180 
KRLLRIYARR LHSNLVFALE QLTSRARANR IAEGAGAMID GLYIRHALGA DAPDAASAIA 

       190 
LVEDYIAIQL SGQPSAEN 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN29485.1.
CP002997 Genomic DNA. Translation: AEM17902.1.
RefSeqNP_697570.1. NC_004310.3.
YP_005615394.1. NC_017251.1.

3D structure databases

ProteinModelPortalQ8G1Z7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR0554.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN29485; AAN29485; BR0554.
AEM17902; AEM17902; BS1330_I0550.
GeneID1166216.
12136870.
KEGGbms:BR0554.
bsi:BS1330_I0550.
PATRIC17789407. VBIBruSui107850_0571.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1309.
HOGENOMHOG000248227.
KOK02167.
OMAGIINHYF.
OrthoDBEOG6FFS5N.
ProtClustDBPRK00767.

Enzyme and pathway databases

UniPathwayUPA00529.

Family and domain databases

Gene3D1.10.357.10. 1 hit.
HAMAPMF_00768. HTH_type_BetI.
InterProIPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
IPR017757. Tscrpt_rep_BetI.
[Graphical view]
PfamPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSPR00455. HTHTETR.
SUPFAMSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
TIGRFAMsTIGR03384. betaine_BetI. 1 hit.
PROSITEPS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETI_BRUSU
AccessionPrimary (citable) accession number: Q8G1Z7
Secondary accession number(s): G0K7H4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella suis

Brucella suis (strain 1330): entries and gene names