Q8G1Q6 (RPOZ_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit omega
Short name=RNAP omega subunit
EC=2.7.7.6

Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega

Gene names

Name:	rpoZ
Ordered Locus Names:	BR0651, BS1330_I0647

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP MF_00366
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00366
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	DNA-directed RNA polymerase subunit omega HAMAP MF_00366		PRO_0000128923

Sequences

	Sequence		Length	Mass (Da)
	Q8G1Q6 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 07D0AAC84796A25E	FASTA	133	14,542
	10 20 30 40 50 60 MARVTVEDCV DKVENRFELV LLAGHRARQI SQGVPITVDR DNDKNPVVAL REIADETLSP 70 80 90 100 110 120 DDLKEDLIHS LQKHVEVDEP EAAPAQIANA AEEIAEGIAE AGEEDVVTFD RMSEEELLAG 130 IEGLVAPEKN DGF

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed: 22038969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN29580.1. CP002997 Genomic DNA. Translation: AEM17997.1.
RefSeq	NP_697665.1. NC_004310.3.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1166314.
GenomeReviews	Gene locus BR0651 in contig AE014291_GR.
KEGG	bms:BR0651.
NMPDR	fig|204722.1.peg.622.
PATRIC	17789595. VBIBruSui107850_0664.
TIGR	BR0651.
Phylogenomic databases
HOGENOM	HBG742204.
OMA	KVDNRFE.
ProtClustDB	PRK00392.
Enzyme and pathway databases
BioCyc	BSUI204722:BR_0651-MONOMER.
Family and domain databases
HAMAP	MF_00366. RNApol_bact_RpoZ. [Tree]
InterPro	IPR003716. DNA-dir_RNA_pol_omega. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Gene3D	G3DSA:3.90.940.10. RNAP_RPB6_omega. 1 hit.
KO	K03060.
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
TIGRFAMs	TIGR00690. RpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_BRUSU

Accession

Primary (citable) accession number: Q8G1Q6
Secondary accession number(s): G0K7Z2

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 20, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program