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Reviewed, UniProtKB/Swiss-Prot Q8G0Z4 (PPNK_BRUSU)

Last modified June 16, 2009. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23
Gene names
Name: ppnK
Ordered Locus Names: BR0937
OrganismBrucella suis [Complete proteome] [HAMAP]
Taxonomic identifier29461 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmetabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
PRO_0000120604

Sequences

Sequence LengthMass (Da)Tools
Q8G0Z4-1 [UniParc].

Last modified November 7, 2003. Version 2.
Checksum: 54ACA8EF3504F74A

FASTA25728,275
        10         20         30         40         50         60 
MKDTSLALHF VSSGTKESLS AQKDLVERYG HVAAEDADII VALGGDGTML QALRDFMNTG 

        70         80         90        100        110        120 
KPIYGMNRGS VGFLMNEFVI ENLPERILAA QMETIRPLVM VAETEDAPPV EALAINEVSL 

       130        140        150        160        170        180 
FRQSYQAARI RITIDGKVRL QELVCDGVMV ATPAGSTAYN LSAQGPILPL EAPLLALTPV 

       190        200        210        220        230        240 
SPFRPRRWGG ALLPKHVTVR MDLLETEKRP VNAVADNNEV KSVTSVTVRE APNSQVTILF 

       250 
DKNHSWDERI LTEQFRH 

« Hide

Cross-references

Sequence databases

AE014291 Genomic DNA. Translation: AAN29863.1. Different initiation.
RefSeqNP_697948.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1166607.
GenomeReviewsGene locus BR0937 in contig AE014291_GR.
KEGGbms:BR0937.
NMPDRfig|204722.1.peg.905.
TIGRBR0937.

Phylogenomic databases

HOGENOMQ8G0Z4.

Enzyme and pathway databases

BioCycBSUI204722:BR_0937-MON.
BRENDA2.7.1.23. 281610.

Family and domain databases

HAMAPMF_00361.
[Tree]
InterProIPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. ATP_NADK.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePPNK_BRUSU
AccessionPrimary (citable) accession number: Q8G0Z4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: November 7, 2003
Last modified: June 16, 2009
This is version 36 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Brucella suis

Brucella suis (strain 1330): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents