Q8G0T3 (Q8G0T3_BRUSU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glutamine synthetase RuleBase RU004356
EC=6.3.1.2 RuleBase RU004356

Gene names

Name:	glnA EMBL AAN29926.1
Ordered Locus Names:	BR1004, BS1330_I1000 EMBL AEM18344.1

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP] EMBL AAN29926.1

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	469 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine. RuleBase RU004356
Subunit structure	Oligomer of 12 subunits arranged in the form of two hexagons By similarity. RuleBase RU000387
Subcellular location	Cytoplasm By similarity RuleBase RU000387.
Sequence similarities	Belongs to the glutamine synthetase family. RuleBase RU000384

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004356 EMBL AAN29926.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamine biosynthetic process Inferred from electronic annotation. Source: InterPro nitrogen fixation Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	glutamate-ammonia ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8G0T3 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 6A62767420CF7191	FASTA	469	52,160
	10 20 30 40 50 60 MTTANDILKQ IKDNDVKFVD LRFTDPKGKL HHVTMDIGLV DEDMFVDGVM FDGSSIAGWK 70 80 90 100 110 120 AINESDMVLM PDPETAHIDP FFAQSTLVIL CDILEPLSGE SYSRDPRTTA KKAEAYLKSL 130 140 150 160 170 180 GIGDTVYVGP EAEFFVFDDV KFKADPFNTG FKLDSAELPS NDDTDYETGN LGHRPRVKGG 190 200 210 220 230 240 YFPVPPIDSL QDMRSEMLTV LSEMGVTVEK HHHEVASAQH ELGTKFDTLV RNADKMQIQK 250 260 270 280 290 300 YVVHQVANAY GKTATFMPKP VFGDNGSGMH VHFSIWKDGK PTFAGNEYAG LSENCLYFIG 310 320 330 340 350 360 GVIKHAKAVN AFTNPSTNSY KRLVPGYEAP VLLAYSARNR SASCRIPFGS SPKSKRLEVR 370 380 390 400 410 420 FPDPSANPYL CFSALLMAGL DGIKNKIHPG QAMDKDLYDL PPKELKQIPT VCGSLREALQ 430 440 450 460 SLDKDREFLK AGGVFSDDQI DSFIELKMAE VMRFEMTPHP VEFDMYYSV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.
[2]	"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.
[3]	"Revised Genome Sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) Cited for: NUCLEOTIDE SEQUENCE. Strain: 1330 EMBL AEM18344.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN29926.1. CP002997 Genomic DNA. Translation: AEM18344.1.
RefSeq	NP_698011.1. NC_004310.3. YP_005615836.1. NC_017251.1.
3D structure databases
SMR	Q8G0T3. Positions 3-469.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BR1004.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN29926; AAN29926; BR1004. AEM18344; AEM18344; BS1330_I1000.
GeneID	1166677. 12138030.
KEGG	bms:BR1004. bsi:BS1330_I1000.
PATRIC	17790318. VBIBruSui107850_1015.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000005157.
KO	K01915.
OMA	FAEGTMF.
ProtClustDB	CLSK862961.
Family and domain databases
Gene3D	3.10.20.70. 1 hit. 3.30.590.10. 1 hit.
InterPro	IPR008147. Gln_synt_beta. IPR014746. Gln_synth/guanido_kin_cat_dom. IPR008146. Gln_synth_cat_dom. IPR027303. Gln_synth_gly_rich_site. IPR004809. Gln_synth_I. IPR001637. Gln_synth_I_adenylation_site. IPR027302. Gln_synth_N_conserv_site. [Graphical view]
Pfam	PF00120. Gln-synt_C. 1 hit. PF03951. Gln-synt_N. 1 hit. [Graphical view]
SUPFAM	SSF54368. Gln_synt_beta. 1 hit.
TIGRFAMs	TIGR00653. GlnA. 1 hit.
PROSITE	PS00180. GLNA_1. 1 hit. PS00182. GLNA_ADENYLATION. 1 hit. PS00181. GLNA_ATP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8G0T3_BRUSU

Accession

Primary (citable) accession number: Q8G0T3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 29, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)