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Protein

Probable peptidyl-prolyl cis-trans isomerase

Gene

ppi

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable peptidyl-prolyl cis-trans isomerase (EC:5.2.1.8)
Short name:
PPIase
Alternative name(s):
Rotamase
Gene namesi
Name:ppi
Ordered Locus Names:BR1094, BS1330_I1090
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000028259627 – 196Probable peptidyl-prolyl cis-trans isomeraseAdd BLAST170

Structurei

3D structure databases

ProteinModelPortaliQ8G0J9.
SMRiQ8G0J9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 194PPIase cyclophilin-typePROSITE-ProRule annotationAdd BLAST166

Sequence similaritiesi

Belongs to the cyclophilin-type PPIase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000065981.
KOiK01802.
OMAiVPVEPVF.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiView protein in InterPro
IPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiView protein in Pfam
PF00160. Pro_isomerase. 1 hit.
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiView protein in PROSITE
PS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8G0J9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFIRSALAA AAFVALSIGA VQTASAADPE NTVILKLKDG DVALELRPDL
60 70 80 90 100
APKHVAQIKK LVREGAYNGV AFHRVIPGFM AQTGDVKFGN MDKGFDAARV
110 120 130 140 150
GTGGSNYPDL PAEFSKEPFV RGTVGMARSQ NPNSANSQFF IMFDDGPFLN
160 170 180 190
GQYTVVGKVV SGMDAVDKIK KGSEAENGAV KNPDKIIKAT IEADTK
Length:196
Mass (Da):20,751
Last modified:March 1, 2003 - v1
Checksum:i5577F02D377FF89B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30014.1.
CP002997 Genomic DNA. Translation: AEM18432.1.
RefSeqiWP_004683823.1. NZ_KN046804.1.

Genome annotation databases

EnsemblBacteriaiAAN30014; AAN30014; BR1094.
AEM18432; AEM18432; BS1330_I1090.
GeneIDi29593701.
KEGGibms:BR1094.
bsi:BS1330_I1090.
PATRICifig|204722.21.peg.2193.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPPI1_BRUSU
AccessioniPrimary (citable) accession number: Q8G0J9
Secondary accession number(s): G0KA16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: March 1, 2003
Last modified: June 7, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families