Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8G0D9

- ISPT_BRUSU

UniProt

Q8G0D9 - ISPT_BRUSU

Protein

Isoprenyl transferase

Gene

uppS

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.UniRule annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei12 – 121UniRule annotation
    Metal bindingi12 – 121MagnesiumUniRule annotation
    Binding sitei17 – 171SubstrateUniRule annotation
    Binding sitei25 – 251SubstrateUniRule annotation
    Binding sitei29 – 291SubstrateUniRule annotation
    Active sitei60 – 601Proton acceptorUniRule annotation
    Binding sitei61 – 611SubstrateUniRule annotation
    Binding sitei63 – 631SubstrateUniRule annotation
    Binding sitei180 – 1801SubstrateUniRule annotation
    Metal bindingi199 – 1991MagnesiumUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. prenyltransferase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isoprenyl transferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
    Gene namesi
    Name:uppSUniRule annotation
    Ordered Locus Names:BR1158, BS1330_I1154
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 254254Isoprenyl transferasePRO_0000123583Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi204722.BR1158.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8G0D9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni13 – 164Substrate bindingUniRule annotation
    Regioni57 – 593Substrate bindingUniRule annotation
    Regioni186 – 1883Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the UPP synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0020.
    HOGENOMiHOG000006056.
    KOiK00806.
    OMAiNRPEQEV.
    OrthoDBiEOG68H89T.

    Family and domain databases

    Gene3Di3.40.1180.10. 1 hit.
    HAMAPiMF_01139. ISPT.
    InterProiIPR001441. UPP_synth-like.
    IPR018520. UPP_synth-like_CS.
    [Graphical view]
    PANTHERiPTHR10291. PTHR10291. 1 hit.
    PfamiPF01255. Prenyltransf. 1 hit.
    [Graphical view]
    SUPFAMiSSF64005. SSF64005. 1 hit.
    TIGRFAMsiTIGR00055. uppS. 1 hit.
    PROSITEiPS01066. UPP_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8G0D9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDPRHIAII MDGNGRWAKA RGLPRSAGHR AGVEALREIV RAAGDRGLGY    50
    LTLFAFSSEN WTRPSGEVSD LLGLLKLFIR RDLAELHRNN VRVNIIGERA 100
    ELAADIRALL NEAESLTHRN TGLNLVIAFN YGSRDEIVRA VRSLARDVAA 150
    GLLDPSSISA ELVSANLDTA GIPDPDLIIR TSGEMRLSNF LLWQAAYSEF 200
    LFLPCHWPDF RPTDLDAAYE TFRQRERRFG GVEPRASADA EEEILCPSTK 250
    GAAV 254
    Length:254
    Mass (Da):28,036
    Last modified:March 1, 2003 - v1
    Checksum:i7FB3772A6719A9CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN30078.1.
    CP002997 Genomic DNA. Translation: AEM18496.1.
    RefSeqiNP_698163.1. NC_004310.3.
    YP_005615988.1. NC_017251.1.

    Genome annotation databases

    EnsemblBacteriaiAAN30078; AAN30078; BR1158.
    AEM18496; AEM18496; BS1330_I1154.
    GeneIDi1166834.
    12138187.
    KEGGibms:BR1158.
    bsi:BS1330_I1154.
    PATRICi17790647. VBIBruSui107850_1177.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN30078.1 .
    CP002997 Genomic DNA. Translation: AEM18496.1 .
    RefSeqi NP_698163.1. NC_004310.3.
    YP_005615988.1. NC_017251.1.

    3D structure databases

    ProteinModelPortali Q8G0D9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BR1158.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN30078 ; AAN30078 ; BR1158 .
    AEM18496 ; AEM18496 ; BS1330_I1154 .
    GeneIDi 1166834.
    12138187.
    KEGGi bms:BR1158.
    bsi:BS1330_I1154.
    PATRICi 17790647. VBIBruSui107850_1177.

    Phylogenomic databases

    eggNOGi COG0020.
    HOGENOMi HOG000006056.
    KOi K00806.
    OMAi NRPEQEV.
    OrthoDBi EOG68H89T.

    Miscellaneous databases

    PROi Q8G0D9.

    Family and domain databases

    Gene3Di 3.40.1180.10. 1 hit.
    HAMAPi MF_01139. ISPT.
    InterProi IPR001441. UPP_synth-like.
    IPR018520. UPP_synth-like_CS.
    [Graphical view ]
    PANTHERi PTHR10291. PTHR10291. 1 hit.
    Pfami PF01255. Prenyltransf. 1 hit.
    [Graphical view ]
    SUPFAMi SSF64005. SSF64005. 1 hit.
    TIGRFAMsi TIGR00055. uppS. 1 hit.
    PROSITEi PS01066. UPP_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiISPT_BRUSU
    AccessioniPrimary (citable) accession number: Q8G0D9
    Secondary accession number(s): G0KA80
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 16, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3