Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8G080

- RL22_BRUSU

UniProt

Q8G080 - RL22_BRUSU

Protein

50S ribosomal protein L22

Gene

rplV

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity.UniRule annotation
    The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L22UniRule annotation
    Gene namesi
    Name:rplVUniRule annotation
    Ordered Locus Names:BR1228, BS1330_I1224
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

    Subcellular locationi

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 12912950S ribosomal protein L22PRO_0000125129Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi204722.BR1228.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8G080.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L22P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0091.
    HOGENOMiHOG000205046.
    KOiK02890.
    OMAiMKRIRPR.
    OrthoDBiEOG6V4GKB.

    Family and domain databases

    Gene3Di3.90.470.10. 1 hit.
    HAMAPiMF_01331_B. Ribosomal_L22_B.
    InterProiIPR001063. Ribosomal_L22.
    IPR018260. Ribosomal_L22/L17_CS.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view]
    PANTHERiPTHR13501. PTHR13501. 1 hit.
    PfamiPF00237. Ribosomal_L22. 1 hit.
    [Graphical view]
    SUPFAMiSSF54843. SSF54843. 1 hit.
    TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
    PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8G080-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKAKAPRQL KDNEAKAVAR TLRVSPQKLN LVASMIRGKK VNAALADLTF    50
    SRKRIAGTVK KTLESAIANA ENNHDLDVDA LIVAEAYVGK SIVMKRFHVR 100
    GRGRASRIEK PFSHLTIVVR EVAEKGEAA 129
    Length:129
    Mass (Da):14,085
    Last modified:March 1, 2003 - v1
    Checksum:i937A6AA72A17F4CA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ227914 Genomic DNA. Translation: ABB77394.1.
    AE014291 Genomic DNA. Translation: AAN30147.1.
    CP002997 Genomic DNA. Translation: AEM18565.1.
    RefSeqiNP_698232.1. NC_004310.3.
    YP_005616057.1. NC_017251.1.

    Genome annotation databases

    EnsemblBacteriaiAAN30147; AAN30147; BR1228.
    AEM18565; AEM18565; BS1330_I1224.
    GeneIDi1166904.
    12138257.
    KEGGibms:BR1228.
    bsi:BS1330_I1224.
    PATRICi17790793. VBIBruSui107850_1250.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ227914 Genomic DNA. Translation: ABB77394.1 .
    AE014291 Genomic DNA. Translation: AAN30147.1 .
    CP002997 Genomic DNA. Translation: AEM18565.1 .
    RefSeqi NP_698232.1. NC_004310.3.
    YP_005616057.1. NC_017251.1.

    3D structure databases

    ProteinModelPortali Q8G080.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BR1228.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN30147 ; AAN30147 ; BR1228 .
    AEM18565 ; AEM18565 ; BS1330_I1224 .
    GeneIDi 1166904.
    12138257.
    KEGGi bms:BR1228.
    bsi:BS1330_I1224.
    PATRICi 17790793. VBIBruSui107850_1250.

    Phylogenomic databases

    eggNOGi COG0091.
    HOGENOMi HOG000205046.
    KOi K02890.
    OMAi MKRIRPR.
    OrthoDBi EOG6V4GKB.

    Family and domain databases

    Gene3Di 3.90.470.10. 1 hit.
    HAMAPi MF_01331_B. Ribosomal_L22_B.
    InterProi IPR001063. Ribosomal_L22.
    IPR018260. Ribosomal_L22/L17_CS.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view ]
    PANTHERi PTHR13501. PTHR13501. 1 hit.
    Pfami PF00237. Ribosomal_L22. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54843. SSF54843. 1 hit.
    TIGRFAMsi TIGR01044. rplV_bact. 1 hit.
    PROSITEi PS00464. RIBOSOMAL_L22. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implications."
      Halling S.M., Jensen A.E.
      BMC Microbiol. 6:84-84(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiRL22_BRUSU
    AccessioniPrimary (citable) accession number: Q8G080
    Secondary accession number(s): Q075T9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 16, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3